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David C. Alsop, PhD


  • Scheidegger R, Wong ET, Alsop DC.Contributors to contrast between glioma and brain tissue in chemical exchange saturation transfer sensitive imaging at 3Tesla.Neuroimage. 2014 May 20.
  • Wang X, Bullock AJ, Zhang L, Wei L, Yu D, Mahagaokar K, Alsop DC, Mier JW, Atkins MB, Coxon A, Oliner J, Bhatt RS.The Role of Angiopoietins as Potential Therapeutic Targets in Renal Cell Carcinoma.Transl Oncol. 2014 Mar 4.
  • Lennerz BS, Alsop DC, Holsen LM, Stern E, Rojas R, Ebbeling CB, Goldstein JM, Ludwig DS.Effects of dietary glycemic index on brain regions related to reward and craving in men.Am J Clin Nutr. 2013 Sep;98(3):641-7.
  • Wang X, Zhang L, O'Neill A, Bahamon B, Alsop DC, Mier JW, Goldberg SN, Signoretti S, Atkins MB, Wood CG, Bhatt RS.Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts.Br J Cancer. 2013 Feb 5;108(2):319-26.
  • Grant AK, Vinogradov E, Wang X, Lenkinski RE, Alsop DC.Perfusion imaging with a freely diffusible hyperpolarized contrast agent.Magn Reson Med. 2011 Mar 22.
  • Bhatt RS, Wang X, Zhang L, Collins MP, Signoretti S, Alsop DC, Goldberg SN, Atkins MB, Mier JW.Renal cancer resistance to antiangiogenic therapy is delayed by restoration of angiostatic signaling.Mol Cancer Ther. 2010 Oct;9(10):2793-802.
  • Alsop DC, Dai W, Grossman M, Detre JA.Arterial spin labeling blood flow MRI: its role in the early characterization of Alzheimer's disease.J. Alzheimers Dis. 2010;20(3):871-80. Review.
  • Dixon WT, Hancu I, Ratnakar SJ, Sherry AD, Lenkinski RE, Alsop DC.A multislice gradient echo pulse sequence for CEST imaging.Magn Reson Med. 2010 Jan;63(1):253-6.
  • Zaharchuk G, Bammer R, Straka M, Shankaranarayan A, Alsop DC, Fischbein NJ, Atlas SW, Moseley ME.Arterial spin-label imaging in patients with normal bolus perfusion-weighted MR imaging findings: pilot identification of the borderzone sign.Radiology. 2009 Sep;252(3):797-807.
  • Schor-Bardach R,Alsop DC,Pedrosa I,Solazzo SA,Wang X,Marquis RP,Atkins MB,Regan M,Signoretti S,Lenkinski RE,Goldberg SN.Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model?.Radiology. 2009 Jun;251(3):731-42.
  • Pedrosa I, Alsop DC, Rofsky NM.Magnetic resonance imaging as a biomarker in renal cell carcinoma.Cancer. 2009 May 15;115(10 Suppl):2334-45. Review.
  • Robson PM,Madhuranthakam AJ,Dai W,Pedrosa I,Rofsky NM,Alsop DC.Strategies for reducing respiratory motion artifacts in renal perfusion imaging with arterial spin labeling.Magn Reson Med. 2009 Jun;61(6):1374-87.
  • de Bazelaire C,Alsop DC,George D,Pedrosa I,Wang Y,Michaelson MD,Rofsky NM.Magnetic resonance imaging-measured blood flow change after antiangiogenic therapy with PTK787/ZK 222584 correlates with clinical outcome in metastatic renal cell carcinoma.Clin Cancer Res. 2008 Sep 1;14(17):5548-54.
  • Wong ET, Alsop D, Lee D, Tam A, Barron L, Bloom J, Gautam S, Wu JK.Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.Cerebrospinal Fluid Res. 2008;5:1.
  • Wang Z, Fernandez-Seara M, Alsop DC, Liu WC, Flax JF, Benasich AA, Detre JA.Assessment of functional development in normal infant brain using arterial spin labeled perfusion MRI.Neuroimage. 2008 Feb 1;39(3):973-8.
  • Bermpohl F, Pascual-Leone A, Amedi A, Merabet LB, Fregni F, Gaab N, Alsop D, Schlaug G, Northoff G.Attentional modulation of emotional stimulus processing: An fMRI study using emotional expectancy.Hum Brain Mapp. 2006 Aug;27(8):662-77.
  • de Bazelaire C, Rofsky NM, Duhamel G, Zhang J, Michaelson MD, George D, Alsop DC.Combined T2* and T1 measurements for improved perfusion and permeability studies in high field using dynamic contrast enhancement.Eur Radiol. 2006 Sep;16(9):2083-91.
  • O'gorman RL, Kumari V, Williams SC, Zelaya FO, Connor SE, Alsop DC, Gray JA.Personality factors correlate with regional cerebral perfusion.Neuroimage. 2006 Jun;31(2):489-95.
  • O'gorman RL, Summers PE, Zelaya FO, Williams SC, Alsop DC, Lythgoe DJ.In vivo estimation of the flow-driven adiabatic inversion efficiency for continuous arterial spin labeling: A method using phase contrast magnetic resonance angiography.Magn Reson Med. 2006 May 3;55(6):1291-1297.
  • Duhamel G, Schlaug G, Alsop DC.Measurement of arterial input functions for dynamic susceptibility contrast magnetic resonance imaging using echoplanar images: comparison of physical simulations with in vivo results.Magn Reson Med. 2006 Mar;55(3):514-23.
  • Bermpohl F, Pascual-Leone A, Amedi A, Merabet LB, Fregni F, Gaab N, Alsop D, Schlaug G, Northoff G.Dissociable networks for the expectancy and perception of emotional stimuli in the human brain.Neuroimage. 2006 Apr 1;30(2):588-600.
  • Garcia DM, Duhamel G, Alsop DC.Efficiency of inversion pulses for background suppressed arterial spin labeling.Magn Reson Med. 2005 Aug;54(2):366-72.
  • Walker MP, Stickgold R, Alsop D, Gaab N, Schlaug G.Sleep-dependent motor memory plasticity in the human brain.Neuroscience. 2005;133(4):911-7.
  • Koelsch S, Fritz T, Schulze K, Alsop D, Schlaug G.Adults and children processing music: an fMRI study.Neuroimage. 2005 May 1;25(4):1068-76.
  • De Bazelaire C, Rofsky NM, Duhamel G, Michaelson MD, George D, Alsop DC.Arterial spin labeling blood flow magnetic resonance imaging for the characterization of metastatic renal cell carcinoma(1).Acad Radiol. 2005 Mar;12(3):347-57.
  • Wang J, Zhang Y, Wolf RL, Roc AC, Alsop DC, Detre JA.Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study.Radiology. 2005 Apr;235(1):218-28.
  • Overy K, Norton AC, Cronin KT, Gaab N, Alsop DC, Winner E, Schlaug G.Imaging melody and rhythm processing in young children.Neuroreport. 2004 Aug 6;15(11):1723-6.
  • Ances BM, McGarvey ML, Abrahams JM, Maldjian JA, Alsop DC, Zager EL, Detre JA.Continuous arterial spin labeled perfusion magnetic resonance imaging in patients before and after carotid endarterectomy.J Neuroimaging. 2004 Apr;14(2):133-8.
  • de Bazelaire CM, Duhamel GD, Rofsky NM, Alsop DC.MR imaging relaxation times of abdominal and pelvic tissues measured in vivo at 3.0 T: preliminary results.Radiology. 2004 Mar;230(3):652-9.
  • Wang J, Li L, Roc AC, Alsop DC, Tang K, Butler NS, Schnall MD, Detre JA.Reduced susceptibility effects in perfusion fMRI with single-shot spin-echo EPI acquisitions at 1.5 Tesla.Magn Reson Imaging. 2004 Jan;22(1):1-7.
  • Grossman M, Koenig P, DeVita C, Glosser G, Moore P, Gee J, Detre J, Alsop D.Neural basis for verb processing in Alzheimer's disease: an fMRI study.Neuropsychology. 2003 Oct;17(4):658-74.
  • Wang J, Alsop DC, Song HK, Maldjian JA, Tang K, Salvucci AE, Detre JA.Arterial transit time imaging with flow encoding arterial spin tagging (FEAST).Magn Reson Med. 2003 Sep;50(3):599-607.
  • Takahashi M, Uematsu H, Alsop DC.[Diffusion imaging].Nippon Igaku Hoshasen Gakkai Zasshi. 2003 May;63(5 Suppl):2-7.
  • Duhamel G, de Bazelaire C, Alsop DC.Evaluation of systematic quantification errors in velocity-selective arterial spin labeling of the brain.Magn Reson Med. 2003 Jul;50(1):145-53.
  • Cooke A, DeVita C, Gee J, Alsop D, Detre J, Chen W, Grossman M.Neural basis for sentence comprehension deficits in frontotemporal dementia.Brain Lang. 2003 May;85(2):211-21.
  • Grossman M, Cooke A, DeVita C, Lee C, Alsop D, Detre J, Gee J, Chen W, Stern MB, Hurtig HI.Grammatical and resource components of sentence processing in Parkinson's disease: an fMRI study.Neurology. 2003 Mar 11;60(5):775-81.
  • Wolf RL, Alsop DC, McGarvey ML, Maldjian JA, Wang J, Detre JA.Susceptibility contrast and arterial spin labeled perfusion MRI in cerebrovascular disease.J Neuroimaging. 2003 Jan;13(1):17-27.
  • Grossman M, Koenig P, Glosser G, DeVita C, Moore P, Rhee J, Detre J, Alsop D, Gee J,.Neural basis for semantic memory difficulty in Alzheimer's disease: an fMRI study.Brain. 2003 Feb;126(Pt 2):292-311.
  • Gunning-Dixon FM, Gur RC, Perkins AC, Schroeder L, Turner T, Turetsky BI, Chan RM, Loughead JW, Alsop DC, Maldjian J, Gur RE.Age-related differences in brain activation during emotional face processing.Neurobiol Aging. 2003 Mar-Apr;24(2):285-95.
  • Gur RE, McGrath C, Chan RM, Schroeder L, Turner T, Turetsky BI, Kohler C, Alsop D, Maldjian J, Ragland JD, Gur RC.An fMRI study of facial emotion processing in patients with schizophrenia.Am J Psychiatry. 2002 Dec;159(12):1992-9.
  • Wang J, Alsop DC, Li L, Listerud J, Gonzalez-At JB, Schnall MD, Detre JA.Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla.Magn Reson Med. 2002 Aug;48(2):242-54.
  • Gur RC, Schroeder L, Turner T, McGrath C, Chan RM, Turetsky BI, Alsop D, Maldjian J, Gur RE.Brain activation during facial emotion processing.Neuroimage. 2002 Jul;16(3 Pt 1):651-62.
  • Polk TA, Stallcup M, Aguirre GK, Alsop DC, D'Esposito M, Detre JA, Farah MJ.Neural specialization for letter recognition.J Cogn Neurosci. 2002 Feb 15;14(2):145-59.
  • Grossman M, Koenig P, DeVita C, Glosser G, Alsop D, Detre J, Gee J.The neural basis for category-specific knowledge: an fMRI study.Neuroimage. 2002 Apr;15(4):936-48.
  • Casasanto DJ, Killgore WD, Maldjian JA, Glosser G, Alsop DC, Cooke AM, Grossman M, Detre JA.Neural correlates of successful and unsuccessful verbal memory encoding.Brain Lang. 2002 Mar;80(3):287-95.
  • Grossman M, Cooke A, DeVita C, Chen W, Moore P, Detre J, Alsop D, Gee J.Sentence processing strategies in healthy seniors with poor comprehension: an fMRI study.Brain Lang. 2002 Mar;80(3):296-313.
  • Aguirre GK, Detre JA, Zarahn E, Alsop DC.Experimental design and the relative sensitivity of BOLD and perfusion fMRI.Neuroimage. 2002 Mar;15(3):488-500.
  • Grossman M, Koenig P, DeVita C, Glosser G, Alsop D, Detre J, Gee J.Neural representation of verb meaning: an fMRI study.Hum Brain Mapp. 2002 Feb;15(2):124-34.
  • Cooke A, Zurif EB, DeVita C, Alsop D, Koenig P, Detre J, Gee J, Pinăngo M, Balogh J, Grossman M.Neural basis for sentence comprehension: grammatical and short-term memory components.Hum Brain Mapp. 2002 Feb;15(2):80-94.
  • Grossman M, Cooke A, DeVita C, Alsop D, Detre J, Chen W, Gee J.Age-related changes in working memory during sentence comprehension: an fMRI study.Neuroimage. 2002 Feb;15(2):302-17.
  • Alsop D.Brain activity mapping with functional MR imaging.Acad Radiol. 2001 Dec;8(12):1195-7.
  • De Boeck G, Alsop D, Wood C.Cortisol effects on aerobic and anaerobic metabolism, nitrogen excretion, and whole-body composition in juvenile rainbow trout.Physiol Biochem Zool. 2001 Nov-Dec;74(6):858-68.
  • Chalela JA, Kasner SE, McGarvey M, Alsop DC, Detre JA.Continuous arterial spin labeling perfusion magnetic resonance imaging findings in postpartum vasculopathy.J Neuroimaging. 2001 Oct;11(4):444-6.
  • Wolf RL, Alsop DC, Levy-Reis I, Meyer PT, Maldjian JA, Gonzalez-Atavales J, French JA, Alavi A, Detre JA.Detection of mesial temporal lobe hypoperfusion in patients with temporal lobe epilepsy by use of arterial spin labeled perfusion MR imaging.AJNR Am J Neuroradiol. 2001 Aug;22(7):1334-41.
  • Maldjian JA, Detre JA, Killgore WD, Judy K, Alsop D, Grossman M, Glosser G.Neuropsychologic performance after resection of an activation cluster involved in cognitive memory function.AJR Am J Roentgenol. 2001 Feb;176(2):541-4.
  • Levy-Reis I, Casasanto DJ, Gonzalez JB, Alsop DC, Glosser G, Maldjan JA, French J, Detre JA.Cortical reorganization in linear nevus sebaceous syndrome: a multimodality neuroimaging study.J Neuroimaging. 2000 Oct;10(4):225-8.
  • Gur RC, Alsop D, Glahn D, Petty R, Swanson CL, Maldjian JA, Turetsky BI, Detre JA, Gee J, Gur RE.An fMRI study of sex differences in regional activation to a verbal and a spatial task.Brain Lang. 2000 Sep;74(2):157-70.
  • Smith DH, Nonaka M, Miller R, Leoni M, Chen XH, Alsop D, Meaney DF.Immediate coma following inertial brain injury dependent on axonal damage in the brainstem.J Neurosurg. 2000 Aug;93(2):315-22.
  • Rizi RR, Ahn S, Alsop DC, Garrett-Roe S, Mescher M, Richter W, Schnall MD, Leigh JS, Warren WS.Intermolecular zero-quantum coherence imaging of the human brain.Magn Reson Med. 2000 May;43(5):627-32.
  • Gonzalez-At JB, Alsop DC, Detre JA.Cerebral perfusion and arterial transit time changes during task activation determined with continuous arterial spin labeling.Magn Reson Med. 2000 May;43(5):739-46.
  • Alsop DC, Detre JA, Grossman M.Assessment of cerebral blood flow in Alzheimer's disease by spin-labeled magnetic resonance imaging.Ann Neurol. 2000 Jan;47(1):93-100.
  • Killgore WD, Glosser G, Casasanto DJ, French JA, Alsop DC, Detre JA.Functional MRI and the Wada test provide complementary information for predicting post-operative seizure control.Seizure. 1999 Dec;8(8):450-5.
  • Detre JA, Samuels OB, Alsop DC, Gonzalez-At JB, Kasner SE, Raps EC.Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis.J Magn Reson Imaging. 1999 Nov;10(5):870-5.
  • Detre JA, Alsop DC.Perfusion magnetic resonance imaging with continuous arterial spin labeling: methods and clinical applications in the central nervous system.Eur J Radiol. 1999 May;30(2):115-24.
  • Hatabu H, Alsop DC, Listerud J, Bonnet M, Gefter WB.T2* and proton density measurement of normal human lung parenchyma using submillisecond echo time gradient echo magnetic resonance imaging.Eur J Radiol. 1999 Mar;29(3):245-52.
  • Maldjian JA, Gottschalk A, Patel RS, Detre JA, Alsop DC.The sensory somatotopic map of the human hand demonstrated at 4 Tesla.Neuroimage. 1999 Jul;10(1):55-62.
  • Yousem DM, Maldjian JA, Hummel T, Alsop DC, Geckle RJ, Kraut MA, Doty RL.The effect of age on odor-stimulated functional MR imaging.AJNR Am J Neuroradiol. 1999 Apr;20(4):600-8.
  • Maldjian JA, Gottschalk A, Patel RS, Pincus D, Detre JA, Alsop DC.Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study.Brain Res. 1999 Apr 10;824(2):291-5.
  • Yousem DM, Maldjian JA, Siddiqi F, Hummel T, Alsop DC, Geckle RJ, Bilker WB, Doty RL.Gender effects on odor-stimulated functional magnetic resonance imaging.Brain Res. 1999 Feb 13;818(2):480-7.
  • Alsop DC, Detre JA.Multisection cerebral blood flow MR imaging with continuous arterial spin labeling.Radiology. 1998 Aug;208(2):410-6.
  • Alsop DC, Connick TJ, Mizsei G.A spiral volume coil for improved RF field homogeneity at high static magnetic field strength.Magn Reson Med. 1998 Jul;40(1):49-54.
  • Detre JA, Maccotta L, King D, Alsop DC, Glosser G, D'Esposito M, Zarahn E, Aguirre GK, French JA.Functional MRI lateralization of memory in temporal lobe epilepsy.Neurology. 1998 Apr;50(4):926-32.
  • Detre JA, Alsop DC, Vives LR, Maccotta L, Teener JW, Raps EC.Noninvasive MRI evaluation of cerebral blood flow in cerebrovascular disease.Neurology. 1998 Mar;50(3):633-41.
  • Alsop DC.Phase insensitive preparation of single-shot RARE: application to diffusion imaging in humans.Magn Reson Med. 1997 Oct;38(4):527-33.
  • Chance B, Luo Q, Nioka S, Alsop DC, Detre JA.Optical investigations of physiology: a study of intrinsic and extrinsic biomedical contrast.Philos Trans R Soc Lond B Biol Sci. 1997 Jun 29;352(1354):707-16.
  • Maccotta L, Detre JA, Alsop DC.The efficiency of adiabatic inversion for perfusion imaging by arterial spin labeling.NMR Biomed. 1997 Jun-Aug;10(4-5):216-21.
  • Detre JA, Zager EL, Alsop DC, Harris VA, Welsh FA.Correlation of diffusion MRI and heat shock protein in a rat embolic stroke model.J Neurol Sci. 1997 May 29;148(2):163-9.
  • D'Esposito M, Detre JA, Aguirre GK, Stallcup M, Alsop DC, Tippet LJ, Farah MJ.A functional MRI study of mental image generation.Neuropsychologia. 1997 May;35(5):725-30.
  • Alsop DC.The sensitivity of low flip angle RARE imaging.Magn Reson Med. 1997 Feb;37(2):176-84.
  • Aguirre GK, Detre JA, Alsop DC, D'Esposito M.The parahippocampus subserves topographical learning in man.Cereb Cortex. 1996 Nov-Dec;6(6):823-9.
  • Alsop DC, Detre JA.Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow.J Cereb Blood Flow Metab. 1996 Nov;16(6):1236-49.
  • Alsop DC, Murai H, Detre JA, McIntosh TK, Smith DH.Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging.J Neurotrauma. 1996 Sep;13(9):515-21.
  • Alsop DC, Detre JA, D'Esposito M, Howard RS, Maldjian JA, Grossman M, Listerud J, Flamm ES, Judy KD, Atlas SW.Functional activation during an auditory comprehension task in patients with temporal lobe lesions.Neuroimage. 1996 Aug;4(1):55-9.
  • Detre JA, Alsop DC, Aguirre GK, Sperling MR.Coupling of cortical and thalamic ictal activity in human partial epilepsy: demonstration by functional magnetic resonance imaging.Epilepsia. 1996 Jul;37(7):657-61.
  • Alsop DC, Connick TJ.Optimization of torque-balanced asymmetric head gradient coils.Magn Reson Med. 1996 Jun;35(6):875-86.
  • Maldjian J, Atlas SW, Howard RS, Greenstein E, Alsop D, Detre JA, Listerud J, D'Esposito M, Flamm ES.Functional magnetic resonance imaging of regional brain activity in patients with intracerebral arteriovenous malformations before surgical or endovascular therapy.J Neurosurg. 1996 Mar;84(3):477-83.
  • Atlas SW, Howard RS, Maldjian J, Alsop D, Detre JA, Listerud J, D'Esposito M, Judy KD, Zager E, Stecker M.Functional magnetic resonance imaging of regional brain activity in patients with intracerebral gliomas: findings and implications for clinical management.Neurosurgery. 1996 Feb;38(2):329-38.
  • D'Esposito M, Detre JA, Alsop DC, Shin RK, Atlas S, Grossman M.The neural basis of the central executive system of working memory.Nature. 1995 Nov 16;378(6554):279-81.
  • Detre JA, Sirven JI, Alsop DC, O'Connor MJ, French JA.Localization of subclinical ictal activity by functional magnetic resonance imaging: correlation with invasive monitoring.Ann Neurol. 1995 Oct;38(4):618-24.
  • Randazzo BP, Kesari S, Gesser RM, Alsop D, Ford JC, Brown SM, Maclean A, Fraser NW.Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant.Virology. 1995 Aug 1;211(1):94-101.
  • Smith DH, Meaney DF, Lenkinski RE, Alsop DC, Grossman R, Kimura H, McIntosh TK, Gennarelli TA.New magnetic resonance imaging techniques for the evaluation of traumatic brain injury.J Neurotrauma. 1995 Aug;12(4):573-7.
  • Alsop DC, Hatabu H, Bonnet M, Listerud J, Gefter W.Multi-slice, breathhold imaging of the lung with submillisecond echo times.Magn Reson Med. 1995 May;33(5):678-82.
  • Ford JC, Hackney DB, Alsop DC, Jara H, Joseph PM, Hand CM, Black P.MRI characterization of diffusion coefficients in a rat spinal cord injury model.Magn Reson Med. 1994 May;31(5):488-94.
  • Ford JC, Hackney DB, Joseph PM, Phelan M, Alsop DC, Tabor SL, Hand CM, Markowitz RS, Black P.A method for in vivo high resolution MRI of rat spinal cord injury.Magn Reson Med. 1994 Feb;31(2):218-23.
  • Devlin M, Alsop D, Clapp A, Cottingham D, Fischer M, Gundersen J, Holmes W, Lange A, Lubin P, Meinhold P, Richards P, Smoot G.Preliminary results from the third flight of the Millimeter Anisotropy Experiment (MAX).Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4774-6.