Nir Hacohen, PhD

Publications

• Pe'er D, Hacohen N.Principles and strategies for developing network models in cancer.Cell. 2011 Mar 18;144(6):864-73.
  21414479
• Lin Y, Zhang L, Cai AX, Lee M, Zhang W, Neuberg D, Canning CM, Soiffer RJ, Alyea EP, Ritz J, Hacohen N, Means TK, Wu CJ.Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans.J Clin I
  21403403
• Shapira SD, Hacohen N.Systems biology approaches to dissect mammalian innate immunity.Curr Opin Immunol. 2011 Feb;23(1):71-7. Review.
  21111589
• Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G.IAP inhibitors enhance co-stimulation to promote tumor immunity.J Exp Med. 2010 Sep 27;207(10):2195-206.
  20837698
• Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S, Campanella GS, Abrazinski T, Manice LA, Moita C, Andrews NW, Wu D, Hacohen N, Luster AD.Synaptotagmin-mediated vesicle fusion regulates cell migration.Nat Immunol. 2010 Jun;11(6):495-502.
  20473299
• Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC.Peroxisomes are signaling platforms for antiviral innate immunity.Cell. 2010 May 14;141(4):668-81.
  20451243
• Astier AL, Beriou G, Eisenhaure TM, Anderton SM, Hafler DA, Hacohen N.RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels.J Immunol. 2010 Jan 15;184(2):685-93.
  20018615
• Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C.Rab27a and Rab27b control different steps of
  19966785
• Savina A,Peres A,Cebrian I,Carmo N,Moita C,Hacohen N,Moita LF,Amigorena S.The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells.Immunity. 2009 Apr;30(4):544-55.
  19328020
• Means TK,Mylonakis E,Tampakakis E,Colvin RA,Seung E,Puckett L,Tai MF,Stewart CR,Pukkila-Worley R,Hickman SE,Moore KJ,Calderwood SB,Hacohen N,Luster AD,El Khoury J.Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenge
  19237602
• Ali N,Karlsson C,Aspling M,Hu G,Hacohen N,Scadden DT,Larsson J.Forward RNAi screens in primary human hematopoietic stem/progenitor cells.Blood. 2009 Apr 16;113(16):3690-5.
  19188664
• Guttman M,Amit I,Garber M,French C,Lin MF,Feldser D,Huarte M,Zuk O,Carey BW,Cassady JP,Cabili MN,Jaenisch R,Mikkelsen TS,Jacks T,Hacohen N,Bernstein BE,Kellis M,Regev A,Rinn JL,Lander ES.Chromatin signature reveals over a thousand highly conserved large n
  19182780
• Luo B,Cheung HW,Subramanian A,Sharifnia T,Okamoto M,Yang X,Hinkle G,Boehm JS,Beroukhim R,Weir BA,Mermel C,Barbie DA,Awad T,Zhou X,Nguyen T,Piqani B,Li C,Golub TR,Meyerson M,Hacohen N,Hahn WC,Lander ES,Sabatini DM,Root DE.Highly parallel identification of
  19091943
• Oberdoerffer S,Moita LF,Neems D,Freitas RP,Hacohen N,Rao A.Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.Science. 2008 Aug 1;321(5889):686-91.
  18669861
• Adams EW, Ratner DM, Seeberger PH, Hacohen N.Carbohydrate-mediated targeting of antigen to dendritic cells leads to enhanced presentation of antigen to T cells.Chembiochem. 2008 Jan 25;9(2):294-303.
  18186095
• Root DE, Hacohen N, Hahn WC, Lander ES, Sabatini DM.Genome-scale loss-of-function screening with a lentiviral RNAi library.Nat Methods. 2006 Sep;3(9):715-9. Review.
  16929317
• Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE.A lentiviral RNAi library for human and mouse g
  16564017
• Alcamo E, Hacohen N, Schulte LC, Rennert PD, Hynes RO, Baltimore D.Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs.J Exp Med. 2002 Jan 21;195(2):233-44.
  11805150
• Huang Q, Liu D, Majewski P, Schulte LC, Korn JM, Young RA, Lander ES, Hacohen N.The plasticity of dendritic cell responses to pathogens and their components.Science. 2001 Oct 26;294(5543):870-5.
  11679675