Masao Kaneki, M.D. Ph.D.

Publications

• Sugita H, Kaneki M, Furuhashi S, Hirota M, Takamori H, Baba H.Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein.Mol Cancer Res. 2010 Aug;8(8):1152-63.
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• Shinozaki S, Inoue Y, Yang W, Fukaya M, Carter EA, Ming-Yu Y, Fischman A, Tompkins R, Kaneki M.Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice.Biochem Biophys Res Commun. 2010 Jan 15;391(3):1459-64.
  20034462
• Kaneki M, Shinozaki S, Chang K, Shimizu N.Could insulin sensitization be used as an alternative to intensive insulin therapy to improve the survival of intensive care unit patients with stress-induced hyperglycemia?.Crit Care Med. 2009 Oct;37(10):2856-8.
  19865018
• Kaneki M.[Is ucOC a novel bone-derived anti-diabetogenic hormone in humans?].Clin Calcium. 2009 Sep;19(9):1304-10. Review.
  19721202
• Sugita M, Sugita H, Kaneki M.Farnesyltransferase inhibitor, manumycin a, prevents atherosclerosis development and reduces oxidative stress in apolipoprotein E-deficient mice.Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1390-5.
  17363690
• Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.Oncogene. 2006 Jan 12;25(2):176-85.
  16170353
• Sugita H, Fujimoto M, Yasukawa T, Shimizu N, Sugita M, Yasuhara S, Martyn JA, Kaneki M.Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells.J Biol Chem. 2005 Apr 8;280(14):14203-11.
  15805118
• Yasukawa T, Tokunaga E, Ota H, Sugita H, Martyn JA, Kaneki M.S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance.J Biol Chem. 2005 Mar 4;280(9):7511-8.
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