• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

W. Nicholas Haining, BCh, BM

Publications

  • Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, Diiorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN.The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8(+) T cells.Nat Immunol. 2014 Apr;15(4):373-83.
    24584090
  • Bachireddy P, Hainz U, Rooney M, Pozdnyakova O, Aldridge J, Zhang W, Liao X, Hodi FS, O'Connell K, Haining WN, Goldstein NR, Canning CM, Soiffer RJ, Ritz J, Hacohen N, Alyea EP, Kim HT, Wu CJ.Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion.Blood. 2014 Feb 27;123(9):1412-21.
    24357730
  • Tan Y, Tamayo P, Nakaya H, Pulendran B, Mesirov JP, Haining WN.Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response.Eur J Immunol. 2014 Jan;44(1):285-95.
    24136404
  • Bachireddy P, Hainz U, Rooney M, Pozdnyakova O, Aldridge J, Zhang W, Liao X, Hodi FS, O'Connell K, Haining WN, Goldstein NR, Canning CM, Soiffer RJ, Ritz J, Hacohen N, Alyea EP, Kim HT, Wu CJ.Reversal of in situ T cell exhaustion during effective human anti-leukemia responses to donor lymphocyte infusion.Blood..
  • Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, Alexe G, Iannacone M, Flynn MP, Omid S, Jesneck JL, Imam S, Mempel TR, Mazo IB, Haining WN, von Andrian UH.Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions.Immunity. 2013 Sep 19;39(3):496-507.
    24054328
  • Haining WN.Thinking inside the box: how T cell inhibitory receptors signal.Nat Med. 2012 Sep;18(9):1338-9.
    22961161
  • Butte MJ, Lee SJ, Jesneck J, Keir ME, Haining WN, Sharpe AH.CD28 costimulation regulates genome-wide effects on alternative splicing.PLoS ONE. 2012;7(6):e40032.
    22768209
  • Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL.Densely interconnected transcriptional circuits control cell states in human hematopoiesis.Cell. 2011 Jan 21;144(2):296-309.
    21241896
  • Haining WN, Wherry EJ.Integrating genomic signatures for immunologic discovery.Immunity. 2010 Feb 26;32(2):152-61.
    20189480
  • Kalia V, Sarkar S, Subramaniam S, Haining WN, Smith KA, Ahmed R.Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.Immunity. 2010 Jan 29;32(1):91-103.
    20096608
  • Blackburn SD,Shin H,Haining WN,Zou T,Workman CJ,Polley A,Betts MR,Freeman GJ,Vignali DA,Wherry EJ.Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.Nat Immunol. 2009 Jan;10(1):29-37.
    19043418
  • Haining WN,Davies J,Kanzler H,Drury L,Brenn T,Evans J,Angelosanto J,Rivoli S,Russell K,George S,Sims P,Neuberg D,Li X,Kutok J,Morgan J,Wen P,Demetri G,Coffman RL,Nadler LM.CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans.Clin Cancer Res. 2008 Sep 1;14(17):5626-34.
    18765557
  • Haining WN,Angelosanto J,Brosnahan K,Ross K,Hahn C,Russell K,Drury L,Norton S,Nadler L,Stegmaier K.High-throughput gene expression profiling of memory differentiation in primary human T cells.BMC Immunol. 2008;9:44.
    18673556
  • Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, Golub TR.Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.J Immunol. 2008 Aug 1;181(3):1859-68.
    18641323
  • Sarkar S, Kalia V, Haining WN, Konieczny BT, Subramaniam S, Ahmed R.Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates.J Exp Med. 2008 Mar 17;205(3):625-40.
    18316415
  • Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R.Molecular signature of CD8+ T cell exhaustion during chronic viral infection.Immunity. 2007 Oct;27(4):670-84.
    17950003
  • Maia S, Haining WN, Ansén S, Xia Z, Armstrong SA, Seth NP, Ghia P, den Boer ML, Pieters R, Sallan SE, Nadler LM, Cardoso AA.Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia.Cancer Res. 2005 Nov 1;65(21):10050-8.
    16267031
  • Haining WN, Neuberg DS, Keczkemethy HL, Evans JW, Rivoli S, Gelman R, Rosenblatt HM, Shearer WT, Guenaga J, Douek DC, Silverman LB, Sallan SE, Guinan EC, Nadler LM.Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia.Blood. 2005 Sep 1;106(5):1749-54.
    15920008
  • Haining WN, Cardoso AA, Keczkemethy HL, Fleming M, Neuberg D, DeAngelo DJ, Stone RM, Galinsky I, Silverman LB, Sallan SE, Nadler LM, Guinan EC.Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia.Exp Hematol. 2005 Mar;33(3):286-94.
    15730852
  • Cardoso AA, Veiga JP, Ghia P, Afonso HM, Haining WN, Sallan SE, Nadler LM.Adoptive T-cell therapy for B-cell acute lymphoblastic leukemia: preclinical studies.Blood. 1999 Nov 15;94(10):3531-40.
    10552964