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Michael R. Hamblin, PhD

Publications

  • Arany PR, Cho A, Hunt TD, Sidhu G, Shin K, Hahm E, Huang GX, Weaver J, Chen AC, Padwa BL, Hamblin MR, Barcellos-Hoff MH, Kulkarni AB, J Mooney D.Photoactivation of Endogenous Latent Transforming Growth Factor-β1 Directs Dental Stem Cell Differentiation for Regeneration.Sci Transl Med. 2014 May 28;6(238):238ra69.
    24871130
  • Wachowska M, Gabrysiak M, Muchowicz A, Bednarek W, Barankiewicz J, Rygiel T, Boon L, Mroz P, Hamblin MR, Golab J.5-Aza-2'-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy.Eur J Cancer. 2014 May;50(7):1370-81.
    24559534
  • Vecchio D, Bhayana B, Huang L, Carrasco E, Evans CL, Hamblin MR.Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers.Eur J Med Chem. 2014 Mar 21;75:479-91.
    24561676
  • Mroz P, Vatansever F, Muchowicz A, Hamblin MR.Photodynamic therapy of murine mastocytoma induces specific immune responses against the cancer/testis antigen P1A.Cancer Res. 2013 Nov 1;73(21):6462-70.
    24072749
  • Sharma SK, Krayer M, Sperandio FF, Huang L, Huang YY, Holten D, Lindsey JS, Hamblin MR.Synthesis and evaluation of cationic bacteriochlorin amphiphiles with effective in vitro photodynamic activity against cancer cells at low nanomolar concentration.J Porphyr Phthalocyanines. 2013 1;17(1-2):73-85.
    23956614
  • Xia Y, Gupta GK, Castano AP, Mroz P, Avci P, Hamblin MR.CpG oligodeoxynucleotide as immune adjuvant enhances photodynamic therapy response in murine metastatic breast cancer.J Biophotonics. 2013 Aug 7.
    23922221
  • Vatansever F, Hamblin MR.Far infrared radiation (FIR): its biological effects and medical applications.Photonics Lasers Med. 2012 Nov 1;4:255-266.
    23833705
  • G N, Tan A, Farhatnia Y, Rajadas J, Hamblin MR, Khaw PT, Seifalian AM.Channelrhodopsins: Visual Regeneration & Neural Activation by a Light Switch.New Biotechnology. 2013 May 7.
    23664865
  • St Denis TG, Hamblin MR.Synthesis, bioanalysis and biodistribution of photosensitizer conjugates for photodynamic therapy.Bioanalysis. 2013 May;5(9):1099-114.
    23641699
  • Ferraresi C, Hamblin MR, Parizotto NA.Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light.Photonics Lasers Med. 2012 Nov 1;1(4):267-286.
    23626925
  • Gupta A, Dai T, Hamblin MR.Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice.Lasers Med Sci. 2013 Apr 26.
    23619627
  • Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR.Linezolid and Vancomycin Decrease the Therapeutic Effect of Methylene Blue-Photodynamic therapy in a Mouse Model of MRSA Bacterial Arthritis.Photochem Photobiol. 2013 May;89(3):679-82.
    23311407
  • Kourtesi C, Ball AR, Huang YY, Jachak SM, Vera DM, Khondkar P, Gibbons S, Hamblin MR, Tegos GP.Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation.Open Microbiol J. 2013;7:34-52.
    23569468
  • Vatansever F, Chandran R, Sadasivam M, Chiang LY, Hamblin MR.Multi-Functionality in Theranostic Nanoparticles: is more Always Better?.Journal Of Nanomedicine & Nanotechnology. 2012 Sep 24;3(8).
    23565346
  • Sperandio FF, Giudice FS, Corrêa L, Pinto DS, Hamblin MR, de Sousa SC.Low-level laser therapy can produce increased aggressiveness of dysplastic and oral cancer cell lines by modulation of Akt/mTOR signaling pathway.J Biophotonics. 2013 Apr 2.
    23554211
  • Sperandio FF, Huang YY, Hamblin MR.Antimicrobial Photodynamic Therapy To Kill Gram-Negative Bacteria.Recent Pat Antiinfect Drug Discov. 2013 Apr 1.
    23550545
  • Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT.Photochemical activation of TRPA1 channels in neurons and animals.Nat Chem Biol. 2013 Apr;9(4):257-63.
    23396078
  • Wang M, Maragani S, Huang L, Jeon S, Canteenwala T, Hamblin MR, Chiang LY.Synthesis of decacationic [60]fullerene decaiodides giving photoinduced production of superoxide radicals and effective PDT-mediation on antimicrobial photoinactivation.Eur J Med Chem. 2013 Feb 17;63C:170-184.
    23474903
  • Chibebe Junior J, Fuchs BB, Sabino CP, Junqueira JC, Jorge AO, Ribeiro MS, Gilmore MS, Rice LB, Tegos GP, Hamblin MR, Mylonakis E.Photodynamic and antibiotic therapy impair the pathogenesis of Enterococcus faecium in a whole animal insect model.PLoS ONE. 2013;8(2):e55926.
    23457486
  • Avci P, Sadasivam M, Gupta A, De Melo WC, Huang YY, Yin R, Chandran R, Kumar R, Otufowora A, Nyame T, Hamblin MR.Animal models of skin disease for drug discovery.Expert Opin Drug Discov. 2013 Mar;8(3):331-55.
    23293893
  • Huang YY, Nagata K, Tedford CE, McCarthy T, Hamblin MR.Low-level laser therapy (LLLT) reduces oxidative stress in primary cortical neurons in vitro.J Biophotonics. 2012 Dec 27.
    23281261
  • Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR.Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.Antimicrob Agents Chemother. 2013 Mar;57(3):1238-45.
    23262998
  • Dai T, Gupta A, Huang YY, Sherwood ME, Murray CK, Vrahas MS, Kielian T, Hamblin MR.Blue Light Eliminates Community-Acquired Methicillin-resistant Staphylococcus aureus in Infected Mouse Skin Abrasions.Photomedicine And Laser Surgery. 2013 Feb 13.
    23406384
  • Prates RA, Fuchs BB, Mizuno K, Naqvi Q, Kato IT, Ribeiro MS, Mylonakis E, Tegos GP, Hamblin MR.Effect of virulence factors on the photodynamic inactivation of Cryptococcus neoformans.PLoS ONE. 2013;8(1):e54387.
    23349872
  • Xuan W, Vatansever F, Huang L, Wu Q, Xuan Y, Dai T, Ando T, Xu T, Huang YY, Hamblin MR.Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen.PLoS ONE. 2013;8(1):e53454.
    23308226
  • Sharma SK, Mroz P, Dai T, Huang YY, St Denis TG, Hamblin MR.Photodynamic Therapy for Cancer and for Infections: What Is the Difference?.Isr. J. Chem. 2012 Sep;52(8-9):691-705.
    23248387
  • Yang E, Diers JR, Huang YY, Hamblin MR, Lindsey JS, Bocian DF, Holten D.Molecular Electronic Tuning of Photosensitizers to Enhance Photodynamic Therapy: Synthetic Dicyanobacteriochlorins as a Case Study.Photochem Photobiol. 2012 Nov 20.
    23163632
  • Sperandio FF, Sharma SK, Wang M, Jeon S, Huang YY, Dai T, Nayka S, de Sousa SC, Chiang LY, Hamblin MR.Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C(70) and C(84)O(2) Fullerene Derivatives.Nanomedicine : Nanotechnology, Biology, And Medicine. 2012 Oct 29.
    23117043
  • Huang L, St Denis TG, Xuan Y, Huang YY, Tanaka M, Zadlo A, Sarna T, Hamblin MR.Paradoxical potentiation of methylene blue-mediated antimicrobial photodynamic inactivation by sodium azide: Role of ambient oxygen and azide radicals.Free Radic Biol Med. 2012 Oct 6;53(11):2062-2071.
    23044264
  • Aquino AE, Sene-Fiorese M, Paolillo FR, Duarte FO, Oishi JC, Pena AA, Duarte AC, Hamblin MR, Bagnato VS, Parizotto NA.Low-level laser therapy (LLLT) combined with swimming training improved the lipid profile in rats fed with high-fat diet.Lasers Med Sci. 2012 Nov 14.
    23151893
  • Huang YY, Vecchio D, Avci P, Yin R, Garcia-Diaz M, Hamblin MR.Melanoma resistance to photodynamic therapy: new insights.Biol Chem. 2012 Nov 14.
    23152406
  • Kato IT, Prates RA, Sabino CP, Fuchs BB, Tegos GP, Mylonakis E, Hamblin MR, Ribeiro MS.Antimicrobial photodynamic inactivation inhibits Candida albicans virulence factors and reduces in vivo pathogenicity.Antimicrob Agents Chemother. 2012 Nov 5.
    23129051
  • Assis L, Moretti AI, Abrahão TB, Cury V, Souza HP, Hamblin MR, Parizotto NA.Low-level laser therapy (808 nm) reduces inflammatory response and oxidative stress in rat tibialis anterior muscle after cryolesion.Lasers Surg Med. 2012 Nov;44(9):726-35.
    23001637
  • St Denis TG, Dai T, Hamblin MR.Killing bacterial spores with blue light: when innate resistance meets the power of light.Photochem Photobiol. 2012 Sep 5.
    22946878
  • Huang YY, Balasubramanian T, Yang E, Luo D, Diers JR, Bocian DF, Lindsey JS, Holten D, Hamblin MR.Stable Synthetic Bacteriochlorins for Photodynamic Therapy: Role of Dicyano Peripheral Groups, Central Metal Substitution (2H, Zn, Pd), and Cremophor EL Delivery.ChemMedChem. 2012 Oct 12.
    23065820
  • Vecchio D, Dai T, Huang L, Fantetti L, Roncucci G, Hamblin MR.Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion PDT with RLP068/Cl in infected mouse skin abrasion.J Biophotonics. 2012 Sep 14.
    22987338
  • Gupta A, Avci P, Sadasivam M, Chandran R, Parizotto N, Vecchio D, de Melo WC, Dai T, Chiang LY, Hamblin MR.Shining light on nanotechnology to help repair and regeneration.Biotechnol Adv. 2012 Aug 21.
    22951919
  • Kawakubo M, Eguchi K, Arai T, Kobayashi K, Hamblin MR.Surface layer-preserving photodynamic therapy (SPPDT) in a subcutaneous mouse model of lung cancer.Lasers Surg Med. 2012 Aug;44(6):500-7.
    22752880
  • Mroz P, Hamblin MR.The immunosuppressive side of PDT.Photochem Photobiol Sci. 2011 Mar 24.
    21437314
  • Mroz P, Szokalska A, Wu MX, Hamblin MR.Photodynamic therapy of tumors can lead to development of systemic antigen-specific immune response.PLoS ONE. 2010;5(12):e15194.
    21179470
  • Mroz P, Hashmi JT, Huang YY, Lange N, Hamblin MR.Stimulation of anti-tumor immunity by photodynamic therapy.Expert Rev Clin Immunol. 2011 Jan;7(1):75-91. Review.
    21162652
  • Mroz P, Huang YY, Szokalska A, Zhiyentayev T, Janjua S, Nifli AP, Sherwood ME, Ruzié C, Borbas KE, Fan D, Krayer M, Balasubramanian T, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR.Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy.FASEB J. 2010 Sep;24(9):3160-70.
    20385618
  • Hamblin MR.Introduction to experimental and clinical studies using low-level laser (light) therapy (LLLT).Lasers Surg Med. 2010 Aug;42(6):447-9.
    20662020
  • Chen Z, Zhou S, Chen J, Deng Y, Luo Z, Chen H, Hamblin MR, Huang M.Pentalysine beta-carbonylphthalocyanine zinc: an effective tumor-targeting photosensitizer for photodynamic therapy.ChemMedChem. 2010 Jun 7;5(6):890-8.
    20458713
  • Huang YY, Mroz P, Zhiyentayev T, Sharma SK, Balasubramanian T, Ruzié C, Krayer M, Fan D, Borbas KE, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR.In vitro photodynamic therapy and quantitative structure-activity relationship studies with stable synthetic near-infrared-absorbing bacteriochlorin photosensitizers.J Med Chem. 2010 May 27;53(10):4018-27.
    20441223
  • Park J, Mroz P, Hamblin MR, Yaroslavsky AN.Dye-enhanced multimodal confocal microscopy for noninvasive detection of skin cancers in mouse models.J Biomed Opt.;15(2):026023.
    20459268
  • Mroz P,Bhaumik J,Dogutan DK,Aly Z,Kamal Z,Khalid L,Kee HL,Bocian DF,Holten D,Lindsey JS,Hamblin MR.Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: Role of molecular charge, central metal and hydroxyl radical production.Cancer Lett. 2009 Sep 8;282(1):63-76.
    19346065
  • Castano AP, Mroz P, Wu MX, Hamblin MR.Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model.Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5495-500.
    18378905
  • Garcez AS, Nuez SC, Hamblin MR, Ribeiro MS.Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion.J Endod. 2008 Feb;34(2):138-42.
    18215668
  • Garcez AS, Nunez SC, Lage-Marques JL, Hamblin MR, Ribeiro MS.Photonic real-time monitoring of bacterial reduction in root canals by genetically engineered bacteria after chemomechanical endodontic therapy.Braz Dent J. 2007;18(3):202-7.
    18176710
  • Tawakol A, Castano AP, Gad F, Zahra T, Bashian G, Migrino RQ, Ahmadi A, Stern J, Anatelli F, Chirico S, Shirazi A, Syed S, Fischman AJ, Muller JE, Hamblin MR.Intravascular detection of inflamed atherosclerotic plaques using a fluorescent photosensitizer targeted to the scavenger receptor.Photochem Photobiol Sci. 2008 Jan;7(1):33-9.
    18167594
  • Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, Rahme LG.Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma.PLoS ONE. 2007;2(12):e1356.
    18159239
  • Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Hamblin MR.Photodynamic therapy with fullerenes.Photochem Photobiol Sci. 2007 Nov;6(11):1139-49. Review.
    17973044
  • Demidova-Rice TN, Salomatina EV, Yaroslavsky AN, Herman IM, Hamblin MR.Low-level light stimulates excisional wound healing in mice.Lasers Surg Med. 2007 Oct;39(9):706-15.
    17960752
  • Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T, Hamblin MR.Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism.Free Radic Biol Med. 2007 Sep 1;43(5):711-9.
    17664135
  • Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese WA, Smotrich MH, Hamblin MR.Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time.Lasers Surg Med. 2007 Jul;39(6):543-50.
    17659584
  • Fuchs BB, Tegos GP, Hamblin MR, Mylonakis E.Susceptibility of Cryptococcus neoformans to photodynamic inactivation is associated with cell wall integrity.Antimicrob Agents Chemother. 2007 Aug;51(8):2929-36.
    17548495
  • Tang HM, Hamblin MR, Yow CM.A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens.J Infect Chemother. 2007 Apr;13(2):87-91.
    17458675
  • Mller-Kristensen M, Hamblin MR, Thiel S, Jensenius JC, Takahashi K.Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.J Invest Dermatol. 2007 Jun;127(6):1524-31.
    17363917
  • Anatelli F, Mroz P, Liu Q, Yang C, Castano AP, Swietlik E, Hamblin MR.Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection.Mol Pharm. 2006 Nov-Dec;3(6):654-64.
    17140253
  • Garcez AS, Ribeiro MS, Tegos GP, Nez SC, Jorge AO, Hamblin MR.Antimicrobial photodynamic therapy combined with conventional endodontic treatment to eliminate root canal biofilm infection.Lasers Surg Med. 2007 Jan;39(1):59-66.
    17066481
  • Foley JW, Song X, Demidova TN, Jalil F, Jilal F, Hamblin MR.Synthesis and properties of benzo[a]phenoxazinium chalcogen analogues as novel broad-spectrum antimicrobial photosensitizers.J Med Chem. 2006 Aug 24;49(17):5291-9.
    16913718
  • Castano AP, Mroz P, Hamblin MR.Photodynamic therapy and anti-tumour immunity.Nat Rev Cancer. 2006 Jul;6(7):535-45. Review.
    16794636
  • Borbas KE, Mroz P, Hamblin MR, Lindsey JS.Bioconjugatable porphyrins bearing a compact swallowtail motif for water solubility.Bioconjug Chem. 2006 May-Jun;17(3):638-53.
    16704201
  • Tegos GP, Demidova TN, Arcila-Lopez D, Lee H, Wharton T, Gali H, Hamblin MR.Cationic fullerenes are effective and selective antimicrobial photosensitizers.Chem Biol. 2005 Oct;12(10):1127-35.
    16242655
  • Liu Q, Hamblin MR.Macrophage-targeted photodynamic therapy: scavenger receptor expression and activation state.Int J Immunopathol Pharmacol. 2005 Jul-Sep;18(3):391-402.
    16164823
  • Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR.Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria.J Photochem Photobiol B. 2005 Oct 3;81(1):15-25.
    16040251
  • Lambrechts SA, Demidova TN, Aalders MC, Hasan T, Hamblin MR.Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice.Photochem Photobiol Sci. 2005 Jul;4(7):503-9.
    15986057
  • Hamblin MR, Viveiros J, Yang C, Ahmadi A, Ganz RA, Tolkoff MJ.Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light.Antimicrob Agents Chemother. 2005 Jul;49(7):2822-7.
    15980355
  • Demidova TN, Hamblin MR.Effect of cell-photosensitizer binding and cell density on microbial photoinactivation.Antimicrob Agents Chemother. 2005 Jun;49(6):2329-35.
    15917529
  • Ganz RA, Viveiros J, Ahmad A, Ahmadi A, Khalil A, Tolkoff MJ, Nishioka NS, Hamblin MR.Helicobacter pylori in patients can be killed by visible light.Lasers Surg Med. 2005 Apr;36(4):260-5.
    15791671
  • Khadem J, Martino M, Anatelli F, Dana MR, Hamblin MR.Healing of perforating rat corneal incisions closed with photodynamic laser-activated tissue glue.Lasers Surg Med. 2004;35(4):304-11.
    15493025
  • Demidova TN, Hamblin MR.Photodynamic therapy targeted to pathogens.Int J Immunopathol Pharmacol. 2004 Sep-Dec;17(3):245-54.
    15461858
  • Demidova TN, Hamblin MR.Macrophage-targeted photodynamic therapy.Int J Immunopathol Pharmacol. 2004 May-Aug;17(2):117-26.
    15171812
  • Gad F, Zahra T, Hasan T, Hamblin MR.Effects of growth phase and extracellular slime on photodynamic inactivation of gram-positive pathogenic bacteria.Antimicrob Agents Chemother. 2004 Jun;48(6):2173-8.
    15155218
  • Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekowitz RA.Mannose-binding Lectin-deficient Mice Are Susceptible to Infection with Staphylococcus aureus.J Exp Med. 2004 May 17;199(10):1379-90.
    15148336
  • Hamblin MR, Hasan T.Photodynamic therapy: a new antimicrobial approach to infectious disease?.Photochem Photobiol Sci. 2004 May;3(5):436-50.
    15122361
  • Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR.Targeted photodynamic therapy of established soft-tissue infections in mice.Photochem Photobiol Sci. 2004 May;3(5):451-8.
    15122362
  • Hamblin MR, Miller JL, Rizvi I, Loew HG, Hasan T.Pegylation of charged polymer-photosensitiser conjugates: effects on photodynamic efficacy.Br J Cancer. 2003 Sep 1;89(5):937-43.
    12942129
  • Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T.Optical monitoring and treatment of potentially lethal wound infections in vivo.J Infect Dis. 2003 Jun 1;187(11):1717-25.
    12751029
  • Kodama T, Doukas AG, Hamblin MR.Delivery of ribosome-inactivating protein toxin into cancer cells with shock waves.Cancer Lett. 2003 Jan 10;189(1):69-75.
    12445679
  • Hamblin MR, O'Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, Hasan T.Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria.J Antimicrob Chemother. 2002 Jun;49(6):941-51.
    12039886
  • Hamblin MR, Miller JL, Rizvi I, Ortel B.Degree of substitution of chlorin(e6) conjugated to charged poly-L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells.J Am Diet Assoc. 2002 Apr 01;10:139-152.
  • Kodama T, Doukas AG, Hamblin MR.Shock wave-mediated molecular delivery into cells.Biochim Biophys Acta. 2002 Jan 30;1542(1-3):186-94.
    11853891
  • Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T.Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging.Photochem Photobiol. 2002 Jan;75(1):51-7.
    11837327
  • Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T.Pegylation of a chlorin(e6) polymer conjugate increases tumor targeting of photosensitizer.Cancer Res. 2001 Oct 1;61(19):7155-62.
    11585749
  • Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T.Epidermal growth factor receptor-targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in vivo.Cancer Res. 2001 Jun 1;61(11):4490-6.
    11389080
  • Hamblin MR, Del Governatore M, Rizvi I, Hasan T.Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer.Br J Cancer. 2000 Dec;83(11):1544-51.
    11076666
  • Hamblin MR, Miller JL, Ortel B.Scavenger-receptor targeted photodynamic therapy.Photochem Photobiol. 2000 Oct;72(4):533-40.
    11045726
  • Kodama T, Hamblin MR, Doukas AG.Cytoplasmic molecular delivery with shock waves: importance of impulse.Biophys J. 2000 Oct;79(4):1821-32.
    11023888
  • Del Governatore M, Hamblin MR, Shea CR, Rizvi I, Molpus KG, Tanabe KK, Hasan T.Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorin(e6) immunoconjugate.Cancer Res. 2000 Aug 1;60(15):4200-5.
    10945630
  • Molpus KL, Hamblin MR, Rizvi I, Hasan T.Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates.Gynecol Oncol. 2000 Mar;76(3):397-404.
    10684717
  • Del Governatore M, Hamblin MR, Piccinini EE, Ugolini G, Hasan T.Targeted photodestruction of human colon cancer cells using charged 17.1A chlorin e6 immunoconjugates.Br J Cancer. 2000 Jan;82(1):56-64.
    10638967
  • Khadem J, Veloso AA, Tolentino F, Hasan T, Hamblin MR.Photodynamic tissue adhesion with chlorin(e6) protein conjugates.Invest Ophthalmol Vis Sci. 1999 Dec;40(13):3132-7.
    10586934
  • Hamblin MR, Rajadhyaksha M, Momma T, Soukos NS, Hasan T.In vivo fluorescence imaging of the transport of charged chlorin e6 conjugates in a rat orthotopic prostate tumour.Br J Cancer. 1999 Sep;81(2):261-8.
    10496351
  • Duska LR, Hamblin MR, Miller JL, Hasan T.Combination photoimmunotherapy and cisplatin: effects on human ovarian cancer ex vivo.J Natl Cancer Inst. 1999 Sep 15;91(18):1557-63.
    10491432
  • Momma T, Hamblin MR, Wu HC, Hasan T.Photodynamic therapy of orthotopic prostate cancer with benzoporphyrin derivative: local control and distant metastasis.Cancer Res. 1998 Dec 1;58(23):5425-31.
    9850075
  • Soukos NS, Ximenez-Fyvie LA, Hamblin MR, Socransky SS, Hasan T.Targeted antimicrobial photochemotherapy.Antimicrob Agents Chemother. 1998 Oct;42(10):2595-601.
    9756761
  • Momma T, Hamblin MR, Hasan T.Hormonal modulation of the accumulation of 5-aminolevulinic acid-induced protoporphyrin and phototoxicity in prostate cancer cells.Int J Cancer. 1997 Sep 17;72(6):1062-9.
    9378541
  • Soukos NS, Hamblin MR, Hasan T.The effect of charge on cellular uptake and phototoxicity of polylysine chlorin(e6) conjugates.Photochem Photobiol. 1997 Apr;65(4):723-9.
    9114750
  • Duska LR, Hamblin MR, Bamberg MP, Hasan T.Biodistribution of charged F(ab')2 photoimmunoconjugates in a xenograft model of ovarian cancer.Br J Cancer. 1997;75(6):837-44.
    9062404
  • Hamblin MR, Miller JL, Hasan T.Effect of charge on the interaction of site-specific photoimmunoconjugates with human ovarian cancer cells.Cancer Res. 1996 Nov 15;56(22):5205-10.
    8912858
  • Molpus KL, Kato D, Hamblin MR, Lilge L, Bamberg M, Hasan T.Intraperitoneal photodynamic therapy of human epithelial ovarian carcinomatosis in a xenograft murine model.Cancer Res. 1996 Mar 1;56(5):1075-82.
    8640764
  • Hamblin MR, Newman EL.Photosensitizer targeting in photodynamic therapy. II. Conjugates of haematoporphyrin with serum lipoproteins.J Photochem Photobiol B. 1994 Nov;26(2):147-57.
    7815189
  • Hamblin MR, Newman EL.Photosensitizer targeting in photodynamic therapy. I. Conjugates of haematoporphyrin with albumin and transferrin.J Photochem Photobiol B. 1994 Oct;26(1):45-56.
    7799139
  • Hamblin MR, Newman EL.On the mechanism of the tumour-localising effect in photodynamic therapy.J Photochem Photobiol B. 1994 Apr;23(1):3-8.
    8021748
  • Hamblin MR, Flora JS, Potter BV.myo-Inositol phosphorothioates, phosphatase-resistant analogues of myo-inositol phosphates. Synthesis of DL-myo-inositol 1,4-bisphosphate and DL-myo-inositol 1,4-bisphosphorothioate.Biochem J. 1987 Sep 15;246(3):771-4.
    3689330
  • Hamblin MR, Cummins JH, Potter BV.Mung bean (Phaseolus aureus) nuclease. A mechanistic investigation of the DNA-cleavage reaction using a dinucleoside phosphorothioate.Biochem J. 1987 Feb 1;241(3):827-33.
    3036076
  • Hamblin MR, Potter BV.E. coli Ada regulatory protein repairs the SP diastereoisomer of alkylated DNA.FEBS Lett. 1985 Sep 23;189(2):315-7.
    2995122