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Donald R. Senger, PhD

Publications

  • Senger DR, Davis GE.Angiogenesis.Cold Spring Harb Perspect Biol. 2011 Aug;3(8):a005090.
    21807843
  • Hoang MV, Nagy JA, Senger DR.Active Rac1 improves pathologic VEGF neovessel architecture and reduces vascular leak: mechanistic similarities with angiopoietin-1.Blood. 2011 Feb 3;117(5):1751-60.
    21030561
  • Hoang MV, Nagy JA, Senger DR.Cdc42-mediated inhibition of GSK-3β improves angio-architecture and lumen formation during VEGF-driven pathological angiogenesis.Microvasc Res. 2010 Sep 16.
    20849862
  • Hoang MV, Nagy JA, Fox JE, Senger DR.Moderation of calpain activity promotes neovascular integration and lumen formation during VEGF-induced pathological angiogenesis.PLoS ONE. 2010;5(10):e13612.
    21049044
  • Hoang MV, Smith LE, Senger DR.Calpain inhibitors reduce retinal hypoxia in ischemic retinopathy by improving neovascular architecture and functional perfusion.Biochim Biophys Acta. 2010 Sep 8.
    20804843
  • Hoang MV, Smith LE, Senger DR.Moderate GSK-3β inhibition improves neovascular architecture, reduces vascular leakage, and reduces retinal hypoxia in a model of ischemic retinopathy.Angiogenesis. 2010 Sep;13(3):269-77.
    20809259
  • Senger DR.Vascular endothelial growth factor: much more than an angiogenesis factor.Mol Biol Cell. 2010 Feb;21(3):377-9.
    20124007
  • Davis GE, Senger DR.Extracellular matrix mediates a molecular balance between vascular morphogenesis and regression.Curr Opin Hematol. 2008 May;15(3):197-203. Review.
    18391785
  • Nagy JA, Senger DR.VEGF-A, cytoskeletal dynamics, and the pathological vascular phenotype.Exp Cell Res. 2006 Mar 10;312(5):538-48.
    16310771
  • Davis GE, Senger DR.Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization.Circ Res. 2005 Nov 25;97(11):1093-107.
    16306453
  • Hoang MV, Senger DR.In vivo and in vitro models of Mammalian angiogenesis.Methods Mol Biol. 2005;294:269-85.
    15576918
  • Liu Y, Senger DR.Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells.FASEB J. 2004 Mar;18(3):457-68.
    15003991
  • Hoang MV, Whelan MC, Senger DR.Rho activity critically and selectively regulates endothelial cell organization during angiogenesis.Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1874-9.
    14769914