Alice T. Shaw, MD, PhD

Publications

• Shaw AT, Solomon B.Targeting Anaplastic Lymphoma Kinase in Lung Cancer.Clin Cancer Res. 2011 Apr 5.
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• Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Eng
  21430269
• Neal JW, Shaw AT.One allele's loss is another's gain: alterations of NKX2-8 in non-small cell lung cancer.Clin Cancer Res. 2011 Feb 15;17(4):638-9.
  21163872
• Ou SH, Bazhenova L, Camidge DR, Solomon BJ, Herman J, Kain T, Bang YJ, Kwak EL, Shaw AT, Salgia R, Maki RG, Clark JW, Wilner KD, Iafrate AJ.Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK transl
  21102269
• Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, Ou SH, Dezube BJ, Jänne PA, Costa DB, Varella-Garcia M, Kim WH, Lynch TJ, Fidias P, Stubbs H, Engelman JA, Sequist LV, Tan W, Gandhi L, Mino-Kenudson M, Wei GC, Shreeve SM, Ratain MJ, Settleman J
  20979469
• Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, Lynch TJ, Iafrate AJ.Clinical Features and Outcome of Patients With Non-Sm
  19667264
• Rodig SJ, Mino-Kenudson M, Dacic S, Yeap BY, Shaw A, Barletta JA, Stubbs H, Law K, Lindeman N, Mark E, Janne PA, Lynch T, Johnson BE, Iafrate AJ, Chirieac LR.Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western
  19671850
• Lynch TJ Jr,Blumenschein GR Jr,Engelman JA,Espinoza-Delgado I,Govindan R,Hanke J,Hanna NH,Heymach JV,Hirsch FR,Janne PA,Lilenbaum RC,Natale RB,Riely GJ,Sequist LV,Shapiro GI,Shaw A,Shepherd FA,Socinski M,Sorensen AG,Wakelee HA,Weitzman A.Summary statement
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• Shaw AT, Meissner A, Dowdle JA, Crowley D, Magendantz M, Ouyang C, Parisi T, Rajagopal J, Blank LJ, Bronson RT, Stone JR, Tuveson DA, Jaenisch R, Jacks T.Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.Genes Dev. 2007 Mar 15;21(6
  17369402
• Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T.Mouse models of human non-small-cell lung cancer: raising the bar.Cold Spring Harb Symp Quant Biol. 2005;70:241-50. Review.
  16869760
• Shaw AT, Kirsch DG, Jacks T.Future of early detection of lung cancer: the role of mouse models.Clin Cancer Res. 2005 Jul 1;11(13 Pt 2):4999s-5003s.
  16000603
• Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T.Endogenous oncogenic K-ras(G12D) stimulates proliferation
  15093544
• Tsang AP, Fujiwara Y, Hom DB, Orkin SH.Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG.Genes Dev. 1998 Apr 15;12(8):1176-88.
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• Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, Weiss MJ, Crossley M, Orkin SH.FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation.Cell. 1997 Jul 11;90(1):109-19.
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• Crossley M, Tsang AP, Bieker JJ, Orkin SH.Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1.J Biol Chem. 1994 Jun 3;269(22):15440-4.
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• Protic M, Hirschfeld S, Tsang AP, Wagner M, Dixon K, Levine AS.Induction of a novel damage-specific DNA binding protein correlates with enhanced DNA repair in primate cells.Mol Toxicol. 1989 Oct-Dec;2(4):255-70.
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