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Chinweike Ukomadu, MD, PhD

Publications

  • Demchev V, Malana G, Vangala D, Stoll J, Desai A, Kang HW, Li Y, Nayeb-Hashemi H, Niepel M, Cohen DE, Ukomadu C.Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization.PLoS ONE. 2013;8(3):e58084.
    23483972
  • Tien AL, Senbanerjee S, Kulkarni A, Mudbhary R, Goudreau B, Ganesan S, Sadler KC, Ukomadu C.UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis.Biochem J. 2011 Apr 1;435(1):175-85.
    21214517
  • Feng S, Cokus SJ, Zhang X, Chen PY, Bostick M, Goll MG, Hetzel J, Jain J, Strauss SH, Halpern ME, Ukomadu C, Sadler KC, Pradhan S, Pellegrini M, Jacobsen SE.Conservation and divergence of methylation patterning in plants and animals.Proc Natl Acad Sci U S A. 2010 May 11;107(19):8689-94.
    20395551
  • Sahni VA,Raghunathan G,Mearadji B,Ukomadu C,Glickman J,Silverman SG,Erturk SM,Mortele KJ.Autoimmune hepatitis: CT and MR imaging features with histopathological correlation.Abdom Imaging. 2010 Feb;35(1):75-84.
    19067033
  • Hammond SP, Borchelt AM, Ukomadu C, Ho VT, Baden LR, Marty FM.Hepatitis B virus reactivation following allogeneic hematopoietic stem cell transplantation.Biol Blood Marrow Transplant. 2009 Sep;15(9):1049-59.
    19660717
  • Liu Z, Ukomadu C.Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.Biochem Biophys Res Commun. 2008 Jan 25;365(4):729-34.
    18039467
  • Zhu W, Ukomadu C, Jha S, Senga T, Dhar SK, Wohlschlegel JA, Nutt LK, Kornbluth S, Dutta A.Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication.Genes Dev. 2007 Sep 15;21(18):2288-99.
    17761813
  • Kanno K, Wu MK, Agate DS, Fanelli BJ, Wagle N, Scapa EF, Ukomadu C, Cohen DE.Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2.J Biol Chem. 2007 Oct 19;282(42):30728-36.
    17704541
  • Sadler KC, Krahn KN, Gaur NA, Ukomadu C.Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1.Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1570-5.
    17242348
  • Ernkvist M, Aase K, Ukomadu C, Wohlschlegel J, Blackman R, Veitonmäki N, Bratt A, Dutta A, Holmgren L.p130-angiomotin associates to actin and controls endothelial cell shape.FEBS J. 2006 May;273(9):2000-11.
    16640563
  • Gandhi RT, Wurcel A, Lee H, McGovern B, Shopis J, Geary M, Sivamurthy R, Sax PE, Ukomadu C.Response to hepatitis B vaccine in HIV-1-positive subjects who test positive for isolated antibody to hepatitis B core antigen: implications for hepatitis B vaccine strategies.J Infect Dis. 2005 May 1;191(9):1435-41.
    15809901
  • Gandhi RT, Wurcel A, McGovern B, Lee H, Shopis J, Corcoran CP, Toner S, Giachetti C, Dockter J, Sax PE, Ukomadu C.Low prevalence of ongoing hepatitis B viremia in HIV-positive individuals with isolated antibody to hepatitis B core antigen.J Acquir Immune Defic Syndr. 2003 Dec 1;34(4):439-41.
    14615664
  • Ukomadu C, Dutta A.p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.J Biol Chem. 2003 Oct 31;278(44):43586-94.
    12930830
  • Gandhi RT, Wurcel A, Lee H, McGovern B, Boczanowski M, Gerwin R, Corcoran CP, Szczepiorkowski Z, Toner S, Cohen DE, Sax PE, Ukomadu C.Isolated antibody to hepatitis B core antigen in human immunodeficiency virus type-1-infected individuals.Clin Infect Dis. 2003 Jun 15;36(12):1602-5.
    12802762
  • Reddy SI, Ukomadu C.Viral hepatitis and hepatocellular carcinoma in African Americans.Cancer Epidemiol Biomarkers Prev. 2003 Mar;12(3):248s-251s.
    12646520
  • Ukomadu C, Dutta A.Inhibition of cdk2 activating phosphorylation by mevastatin.J Biol Chem. 2003 Feb 14;278(7):4840-6.
    12475985
  • Soetikno RM, Piper J, Montes H, Ukomadu C, Carr-Locke DL.Use of endoscopic band ligation to treat a Dieulafoy's lesion of the esophagus.Endoscopy. 2000 Apr;32(4):S15.
    10774980
  • Vandervoort J, Montes H, Soetikno RM, Ukomadu C, Carr-Locke DL.Use of endoscopic band ligation in the treatment of ongoing rectal bleeding.Gastrointest Endosc. 1999 Mar;49(3 Pt 1):392-4.
    10049429
  • Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS.Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis.Neuron. 1993 Apr;10(4):667-78.
    8386527
  • Ukomadu C, Zhou J, Sigworth FJ, Agnew WS.muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties.Neuron. 1992 Apr;8(4):663-76.
    1314619
  • Agnew WS, Cooper EC, Shenkel S, Correa AM, James WM, Ukomadu C, Tomiko SA.Voltage-sensitive sodium channels: agents that perturb inactivation gating.Ann N Y Acad Sci. 1991;625:200-23.
    1647724