DF/HCC Program Affiliation

Breast Cancer
Outcomes Research

Research Abstract

My research experiences and interests center on the development and utilization of population-based computer simulation models of the natural history of cancer to inform decision making in health policy and improve population health. Specifically, I am interested in the development and application of breast and cervical cancer simulation models to cancer prevention and control. My work is motivated by the fundamental concern for improving both methodology and the information available for decision making at both individual and population levels. My current research agenda includes 1) quantifying outcomes of interest such as the risk of a false positive test result or the reduction in cancer mortality under alternative screening strategies to inform individuals about trade-offs in benefits and risks from participation in those strategies; and 2) evaluation of breast cancer screening policies in the U.S. to guide policy decisions and resource allocation.

Publications

• Stout NK,Goldie SJ.Keeping the noise down: common random numbers for disease simulation modeling.Health Care Manag Sci 2008 Dec;11(4):399-406.
  18998599
• Stout NK,Goldhaber-Fiebert JD,Ortendahl JD,Goldie SJ.Trade-offs in cervical cancer prevention: balancing benefits and risks.Arch Intern Med 2008 Sep 22;168(17):1881-9.
  18809815
• Goldhaber-Fiebert JD, Stout NK, Salomon JA, Kuntz KM, Goldie SJ.Cost-effectiveness of cervical cancer screening with human papillomavirus DNA testing and HPV-16,18 vaccination.Journal of the National Cancer Institute 2008 Mar 5;100(5):308-20.
  18314477
• Tosteson AN,Stout NK,Fryback DG,Acharyya S,Herman BA,Hannah LG,Pisano ED.Cost-effectiveness of digital mammography breast cancer screening.Ann Intern Med 2008 Jan 1;148(1):1-10.
  18166758
• Kim JJ, Kuntz KM, Stout NK, Mahmud S, Villa LL, Franco EL, Goldie SJ.Multiparameter calibration of a natural history model of cervical cancer.Am J Epidemiol 2007 Jul 15;166(2):137-50.
  17526866
• Fryback DG,Stout NK,Rosenberg MA,Trentham-Dietz A,Kuruchittham V,Remington PL.The Wisconsin Breast Cancer Epidemiology Simulation Model.J Natl Cancer Inst Monogr 2006(36):37-47.
  17032893
• Stout NK,Rosenberg MA,Trentham-Dietz A,Smith MA,Robinson SM,Fryback DG.Retrospective cost-effectiveness analysis of screening mammography.Journal of the National Cancer Institute 2006 Jun 7;98(11):774-82.
  16757702
• Goldhaber-Fiebert JD, Stout NK, Ortendahl J, Kuntz KM, Goldie SJ, Salomon JA.Modeling human papillomavirus and cervical cancer in the United States for analyses of screening and vaccination.Popul Health Metr 2007;5:11.
  17967185