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Pankaj Seth

Publications

  • Xie H, Hanai JI, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M, Lane AN, Higashi RM, Fan TW, Pandolfi PP, Sukhatme VP, Seth P.Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells.Cell Metab. 2014 Apr 9.
    24726384
  • Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, Umbricht C, Sukumar S, Seth P, Sukhatme VP, Jakkula LR, Lu Y, Mills GB, Cho RJ, Collisson EA, van't Veer LJ, Spellman PT, Gray JW.Modeling precision treatment of breast cancer.Genome Biol. 2013;14(10):R110.
    24176112
  • Husain Z, Seth P, Sukhatme VP.Tumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology.Oncoimmunology. 2013 Nov 1;2(11):e26383.
    24404426
  • Wegiel B, Gallo D, Csizmadia E, Harris C, Belcher J, Vercellotti GM, Penacho N, Seth P, Sukhatme V, Ahmed A, Pandolfi PP, Helczynski L, Bjartell A, Persson JL, Otterbein LE.Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth.Cancer Res. 2013 Dec 1;73(23):7009-21.
    24121491
  • Husain Z, Huang Y, Seth P, Sukhatme VP.Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells.J Immunol. 2013 Aug 1;191(3):1486-95.
    23817426
  • Sun X, Han L, Seth P, Bian S, Li L, Csizmadia E, Junger WG, Schmelzle M, Usheva A, Tapper EB, Baffy G, Sukhatme VP, Wu Y, Robson SC.Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/Entpd1 null mice.Hepatology. 2012 Aug 1.
    22859060
  • Seth P, Grant A, Tang J, Vinogradov E, Wang X, Lenkinski R, Sukhatme VP.On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.Neoplasia. 2011 Jan;13(1):60-71.
    21245941
  • Ren JG, Seth P, Everett P, Clish CB, Sukhatme VP.Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.PLoS ONE. 2010;5(9).
    20824065
  • Xie H,Valera VA,Merino MJ,Amato AM,Signoretti S,Linehan WM,Sukhatme VP,Seth P.LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer.Mol Cancer Ther. 2009 Mar;8(3):626-35.
    19276158
  • Wei F,Karihaloo A,Yu Z,Marlier A,Seth P,Shibazaki S,Wang T,Sukhatme VP,Somlo S,Cantley LG.Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.Kidney Int. 2008 Nov;74(10):1310-8.
    18974761
  • Jones CA,London NR,Chen H,Park KW,Sauvaget D,Stockton RA,Wythe JD,Suh W,Larrieu-Lahargue F,Mukouyama YS,Lindblom P,Seth P,Frias A,Nishiya N,Ginsberg MH,Gerhardt H,Zhang K,Li DY.Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.Nat Med. 2008 Apr;14(4):448-53.
    18345009