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Zhe Li

Publications

  • Baena E, Shao Z, Linn DE, Glass K, Hamblen MJ, Fujiwara Y, Kim J, Nguyen M, Zhang X, Godinho FJ, Bronson RT, Mucci LA, Loda M, Yuan GC, Orkin SH, Li Z.ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.Genes Dev. 2013 Mar 15;27(6):683-98.
    23512661
  • Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM.A public resource facilitating clinical use of genomes.Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11920-7.
    22797899
  • Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K.Somatic coding mutations in human induced pluripotent stem cells.Nature. 2011 Mar 3;471(7336):63-7.
    21368825
  • Klusmann JH, Godinho FJ, Heitmann K, Maroz A, Koch ML, Reinhardt D, Orkin SH, Li Z.Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis.Genes Dev. 2010 Aug 1;24(15):1659-72.
    20679399
  • Alford K, Slender A, Vanes L, Li Z, Fisher EM, Nizetic D, Orkin SH, Roberts I, Tybulewicz VL.Perturbed hematopoiesis in the Tc1 mouse model of Down Syndrome.Blood. 2010 Apr 8;115(14):2928-37.
    20154221
  • Klusmann JH, Li Z, B√∂hmer K, Maroz A, Koch ML, Emmrich S, Godinho FJ, Orkin SH, Reinhardt D.miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia.Genes Dev. 2010 Mar 1;24(5):478-90.
    20194440
  • Li Z, Huang H, Boland P, Dominguez MG, Burfeind P, Lai KM, Lin HC, Gale NW, Daly C, Auerbach W, Valenzuela D, Yancopoulos GD, Thurston G.Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22399-404.
    20018779
  • Lee JH, Park IH, Gao Y, Li JB, Li Z, Daley GQ, Zhang K, Church GM.A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.PLoS Genet. 2009 Nov;5(11):e1000718.
    19911041
  • Huang Z, Dore LC, Li Z, Orkin SH, Feng G, Lin S, Crispino JD.GATA-2 reinforces megakaryocyte development in the absence of GATA-1.Mol Cell Biol. 2009 Sep;29(18):5168-80.
    19620289
  • Zhang K, Li JB, Gao Y, Egli D, Xie B, Deng J, Li Z, Lee JH, Aach J, Leproust EM, Eggan K, Church GM.Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.Nat Methods. 2009 Aug;6(8):613-8.
    19620972
  • Chen XL,Liu LC,Xu ZG,Li Z,Li RW,Gao RJ,Wang S,Zhang M,Guo H.[Inhibition of bladder cancer cell growth and angiogenesis by co-blockage of vascular endothelial growth factor and its receptor kdr].Zhonghua Zhong Liu Za Zhi. 2008 Aug;30(8):578-82.
    19102933
  • Li Z, Tognon CE, Godinho FJ, Yasaitis L, Hock H, Herschkowitz JI, Lannon CL, Cho E, Kim SJ, Bronson RT, Perou CM, Sorensen PH, Orkin SH.ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.Cancer Cell. 2007 Dec;12(6):542-58.
    18068631
  • Li Z,Godinho FJ,Klusmann JH,Garriga-Canut M,Yu C,Orkin SH.Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1.Nat Genet. 2005 Jun;37(6):613-9.
    15895080