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Paul L. Nguyen, MD


  • Groarke JD, Nguyen PL, Nohria A, Ferrari R, Cheng S, Moslehi J.Cardiovascular complications of radiation therapy for thoracic malignancies: the role for non-invasive imaging for detection of cardiovascular disease.Eur Heart J. 2013 May 10.
  • Parekh A, Chen MH, D'Amico AV, Dosoretz DE, Ross R, Salenius S, Graham PL, Beckman JA, Beard CJ, Choueiri TK, Ennis RD, Hoffman KE, Hu JC, Ma J, Martin NE, Nguyen PL.Identification of comorbidities that place men at highest risk of death from androgen deprivation therapy before brachytherapy for prostate cancer.Brachytherapy. 2013 May 4.
  • Beard CJ, Travis LB, Chen MH, Arvold ND, Nguyen PL, Martin NE, Kuban DA, Ng AK, Hoffman KE.Outcomes in stage I testicular seminoma: A population-based study of 9193 patients.Cancer. 2013 Apr 30.
  • Kim SP, Karnes RJ, Nguyen PL, Ziegenfuss JY, Han LC, Thompson RH, Trinh QD, Sun M, Boorjian SA, Beebe TJ, Tilburt JC.Clinical Implementation of Quality of Life Instruments and Prediction Tools for Localized Prostate Cancer: Results from a National Survey of Radiation Oncologists and Urologists.J Urol. 2012 Dec 3.
  • Kaplan JR, Kowalczyk KJ, Borza T, Gu X, Lipsitz SR, Nguyen PL, Friedlander DF, Trinh QD, Hu JC.Patterns of care and outcomes of radiotherapy for lymph node positivity after radical prostatectomy.BJU Int. 2013 Apr 2.
  • Nguyen PL.Androgen-deprivation Therapy and Cardiovascular Harm: Let's Not Throw Out the Baby with the Bathwater.Eur Urol. 2013 Mar 13.
  • Schoenfeld JD, Margalit DN, Kasperzyk JL, Shui IM, Rider JR, Epstein MM, Meisner A, Kenfield SA, Martin NE, Nguyen PL, Kantoff PW, Giovannucci EL, Stampfer MJ, Mucci LA.A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer.Clin Cancer Res. 2013 Mar 15;19(6):1612-9.
  • Kowalczyk KJ, Choueiri TK, Hevelone ND, Trinh QD, Lipsitz SR, Nguyen PL, Lynch JH, Hu JC.Comparative effectiveness, costs and trends in treatment of small renal masses from 2005 to 2007.BJU Int. 2013 Mar 4.
  • Eberhardt SC, Carter S, Casalino DD, Merrick G, Frank SJ, Gottschalk AR, Leyendecker JR, Nguyen PL, Oto A, Porter C, Remer EM, Rosenthal SA.ACR Appropriateness Criteria prostate cancer--pretreatment detection, staging, and surveillance.J Am Coll Radiol. 2013 Feb;10(2):83-92.
  • Moradi M, Janoos F, Fedorov A, Risholm P, Kapur T, Wolfsberger LD, Nguyen PL, Tempany CM, Wells WM.Two solutions for registration of ultrasound to MRI for image-guided prostate interventions.Conf Proc IEEE Eng Med Biol Soc. 2012;2012:1129-32.
  • Nguyen PL, Devlin PM, Beard CJ, Orio PF, O'Leary MP, Wolfsberger LD, O'Farrell DA, Sweeney CM, Hadaschik BA, Hohenfellner M, Hatiboglu G.High-dose-rate brachytherapy for prostate cancer in a previously radiated patient with polyethylene glycol hydrogel spacing to reduce rectal dose: case report and review of the literature.Brachytherapy.;12(1):77-83.
  • Parekh A, Chen MH, Hoffman KE, Choueiri TK, Hu JC, Bennett CL, Kattan MW, Sartor O, Stein K, Graham PL, D'Amico AV, Nguyen PL.Reduced penile size and treatment regret in men with recurrent prostate cancer after surgery, radiotherapy plus androgen deprivation, or radiotherapy alone.Urology. 2013 Jan;81(1):130-4.
  • Chen RC, Zhang Y, Chen MH, McMahon E, Loffredo M, McPherson CP, Nguyen AU, Nguyen PL, D'Amico AV.Patient-reported quality of life during radiation treatment for localized prostate cancer: results from a prospective phase II trial.BJU Int. 2012 Dec;110(11):1690-5.
  • Khanna A, Hu JC, Gu X, Nguyen PL, Lipsitz S, Palapattu GS.Certificate of Need Programs, Intensity Modulated Radiation Therapy Use and the Cost of Prostate Cancer Care.J Urol. 2012 Nov 16.
  • Nguyen PL.Harms versus benefits with duration of androgen suppression.Lancet Oncol. 2012 Nov 9.
  • Williams SB, Amarasekera CA, Gu X, Lipsitz SR, Nguyen PL, Hevelone ND, Kowalczyk KJ, Hu JC.Influence of surgeon and hospital volume on radical prostatectomy costs.J Urol. 2012 Dec;188(6):2198-204.
  • Martin NE, Chen MH, Nguyen PL, Beard CJ, Loffredo MJ, Kantoff PW, D'Amico AV.Biopsy Gleason score and the duration of testosterone suppression among men treated with external beam radiation and 6 months of combined androgen blockade.BJU Int. 2012 Nov;110(9):1252-6.
  • Nguyen PL, Chen MH, Zhang Y, Tempany CM, Cormack RA, Beard CJ, Hurwitz MD, Suh WW, D'Amico AV.Updated results of magnetic resonance imaging guided partial prostate brachytherapy for favorable risk prostate cancer: implications for focal therapy.J Urol. 2012 Oct;188(4):1151-6.
  • Margalit DN, Sreedhara M, Chen YH, Catalano PJ, Nguyen PL, Golshan M, Overmoyer BA, Harris JR, Brock JE.Microinvasive Breast Cancer: ER, PR, and HER-2/neu Status and Clinical Outcomes after Breast-Conserving Therapy or Mastectomy.Ann Surg Oncol. 2012 Sep 7.
  • Aizer AA, Paly JJ, Zietman AL, Nguyen PL, Beard CJ, Rao SK, Kaplan ID, Niemierko A, Hirsch MS, Wu CL, Olumi AF, Michaelson MD, D'Amico AV, Efstathiou JA.Multidisciplinary care and pursuit of active surveillance in low-risk prostate cancer.J Clin Oncol. 2012 Sep 1;30(25):3071-6.
  • Nguyen PL, Je Y, Schutz FA, Hoffman KE, Hu JC, Parekh A, Beckman JA, Choueiri TK.Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer: a meta-analysis of randomized trials.JAMA. 2011 Dec 7;306(21):2359-66.
  • Rosenberg JE, Chen MH, Nguyen PL, Braccioforte MH, Moran BJ, D'Amico AV.Hormonal Therapy or External-Beam Radiation With Brachytherapy and the Risk of Death From Prostate Cancer in Men With Intermediate Risk Prostate Cancer.Clin Genitourin Cancer. 2011 Nov 28.
  • Nguyen PL, Chen MH, Hoffman KE, Chen RC, Hu JC, Bennett CL, Kattan MW, Sartor O, Stein K, D'Amico AV.Cardiovascular comorbidity and treatment regret in men with recurrent prostate cancer.BJU Int. 2011 Nov 15.
  • Arvold ND, Taghian AG, Niemierko A, Abi Raad RF, Sreedhara M, Nguyen PL, Bellon JR, Wong JS, Smith BL, Harris JR.Age, breast cancer subtype approximation, and local recurrence after breast-conserving therapy.J Clin Oncol. 2011 Oct 10;29(29):3885-91.
  • Chang P, Szymanski KM, Dunn RL, Chipman JJ, Litwin MS, Nguyen PL, Sweeney CJ, Cook R, Wagner AA, DeWolf WC, Bubley GJ, Funches R, Aronovitz JA, Wei JT, Sanda MG.Expanded prostate cancer index composite for clinical practice: development and validation of a practical health related quality of life instrument for use in the routine clinical care of patients with prostate cancer.J Urol. 2011 Sep;186(3):865-72.
  • Prasad SM, Gu X, Lipsitz SR, Nguyen PL, Hu JC.Inappropriate utilization of radiographic imaging in men with newly diagnosed prostate cancer in the United States.Cancer. 2011 Aug 5.
  • Choueiri TK, Schutz FA, Hevelone ND, Nguyen PL, Lipsitz SR, Williams SB, Silverman SG, Hu JC.Thermal Ablation vs Surgery for Localized Kidney Cancer: a Surveillance, Epidemiology, and End Results (SEER) Database Analysis.Urology. 2011 Jul;78(1):93-8.
  • Nguyen PL, Chen MH, Beckman JA, Beard CJ, Martin NE, Choueiri TK, Hu JC, Hoffman KE, Dosoretz DE, Moran BJ, Salenius SA, Braccioforte MH, Kantoff PW, D'Amico AV, Ennis RD.Influence of Androgen Deprivation Therapy on All-Cause Mortality in Men with High-Risk Prostate Cancer and a History of Congestive Heart Failure or Myocardial Infarction.Int J Radiat Oncol Biol Phys. 2011 Jun 25.
  • Kowalczyk KJ, Huang AC, Hevelone ND, Lipsitz SR, Yu HY, Ulmer WD, Kaplan JR, Patel S, Nguyen PL, Hu JC.Stepwise Approach for Nerve Sparing Without Countertraction During Robot-Assisted Radical Prostatectomy: Technique and Outcomes.Eur Urol. 2011 May 17.
  • Hattangadi-Gluth JA, Wo JY, Nguyen PL, Abi Raad RF, Sreedhara M, Niemierko A, Freer PE, Georgian-Smith D, Bellon JR, Wong JS, Smith BL, Harris JR, Taghian AG.Basal Subtype of Invasive Breast Cancer is Associated with a Higher Risk of True Recurrence After Conventional Breast-Conserving Therapy.Int J Radiat Oncol Biol Phys. 2011 May 19.
  • Choi WW, Williams SB, Gu X, Lipsitz SR, Nguyen PL, Hu JC.Overuse of Imaging for Staging Low Risk Prostate Cancer.J Urol. 2011 Mar 16.
  • Nguyen PL, Gu X, Lipsitz SR, Choueiri TK, Choi WW, Lei Y, Hoffman KE, Hu JC.Cost Implications of the Rapid Adoption of Newer Technologies for Treating Prostate Cancer.J Clin Oncol. 2011 Mar 14.
  • Williams SB, Gu X, Lipsitz SR, Nguyen PL, Choueiri TK, Hu JC.Utilization and expense of adjuvant cancer therapies following radical prostatectomy.Cancer. 2011 Mar 1.
  • Kelly PJ, Lin YB, Yu AY, Ropper AE, Nguyen PL, Marcus KJ, Hacker FL, Weiss SE.Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women's Cancer Center experience.J. Neurooncol. 2011 Jan 7.
  • Nguyen PL, Chen MH, Goldhaber SZ, Martin NE, Beard CJ, Dosoretz DE, Katin MJ, Ross R, Salenius SA, D'Amico AV.Coronary revascularization and mortality in men with congestive heart failure or prior myocardial infarction who receive androgen deprivation.Cancer. 2011 Jan 15;117(2):406-13.
  • Choueiri TK, Mayer EL, Je Y, Rosenberg JE, Nguyen PL, Azzi GR, Bellmunt J, Burstein HJ, Schutz FA.Congestive Heart Failure Risk in Patients With Breast Cancer Treated With Bevacizumab.J Clin Oncol. 2011 Jan 4.
  • Hoffman KE, Nguyen PL, Chen MH, Chen RC, Choueiri TK, Hu JC, Kuban DA, D'Amico AV.Recommendations for Post-Prostatectomy Radiation Therapy in the United States Before and After the Presentation of Randomized Trials.J Urol. 2011 Jan;185(1):116-20.
  • Schutz FA, Je Y, Azzi GR, Nguyen PL, Choueiri TK.Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes.Ann Oncol. 2010 Nov 29.
  • Ahove DA, Hoffman KE, Hu JC, Choueiri TK, D'Amico AV, Nguyen PL.Which Patients With Undetectable PSA Levels 5 Years After Radical Prostatectomy Are Still at Risk of Recurrence?-Implications for a Risk-adapted Follow-up Strategy.Urology. 2010 Nov;76(5):1201-5.
  • Nguyen PL, Chen RC, Hoffman KE, Trofimov A, Efstathiou JA, Coen JJ, Shipley WU, Zietman AL, Talcott JA.Rectal Dose-Volume Histogram Parameters Are Associated with Long-Term Patient-Reported Gastrointestinal Quality of Life After Conventional and High-Dose Radiation for Prostate Cancer: A Subgroup Analysis of a Randomized Trial.Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1081-5.
  • Benedettini E, Nguyen P, Loda M.The pathogenesis of prostate cancer: from molecular to metabolic alterations.Diagn Histopathol. 2008 May;14(5):195-201.
  • Trofimov A, Nguyen PL, Efstathiou JA, Wang Y, Lu HM, Engelsman M, Merrick S, Cheng CW, Wong JR, Zietman AL.Interfractional Variations in the Setup of Pelvic Bony Anatomy and Soft Tissue, and Their Implications on the Delivery of Proton Therapy for Localized Prostate Cancer.Int J Radiat Oncol Biol Phys. 2010 Oct 13.
  • Nguyen PL, Ma J, Chavarro JE, Freedman ML, Lis R, Fedele G, Fiore C, Qiu W, Fiorentino M, Finn S, Penney KL, Eisenstein A, Schumacher FR, Mucci LA, Stampfer MJ, Giovannucci E, Loda M.Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival.J Clin Oncol. 2010 Sep 1;28(25):3958-64.
  • Nguyen PL, D'Amico AV.Deciding which patients to treat with salvage radiotherapy after prostatectomy.Oncology (Huntingt). 2010 Jul;24(8):705, 711.
  • Hu JC, Prasad SM, Gu X, Williams SB, Lipsitz SR, Nguyen PL, Choueiri TK, Choi WW, D'Amico AV.Determinants of Performing Radical Prostatectomy Pelvic Lymph Node Dissection and the Number of Lymph Nodes Removed in Elderly Men.Urology. 2010 Aug 16.
  • Nguyen PL, Chen MH, Beard CJ, Suh WW, Renshaw AA, Loffredo M, McMahon E, Kantoff PW, D'Amico AV.Radiation With or Without 6 Months of Androgen Suppression Therapy in Intermediate- and High-Risk Clinically Localized Prostate Cancer: A Postrandomization Analysis by Risk Group.Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1046-52.
  • Nguyen PL, Chen MH, Choueiri TK, Hoffman KE, Hu JC, Martin NE, Beard CJ, Dosoretz DE, Moran BJ, Katin MJ, Braccioforte MH, Ross R, Salenius SA, Kantoff PW, D'Amico AV.Risk of All-Cause and Prostate Cancer-Specific Mortality After Brachytherapy in Men with Small Prostate Size.Int J Radiat Oncol Biol Phys. 2010 Jun 2.
  • Katz MS, Efstathiou JA, D'Amico AV, Kattan MW, Sanda MG, Nguyen PL, Smith MR, Carroll PR, Zietman AL.The 'CaP Calculator': an online decision support tool for clinically localized prostate cancer.BJU Int. 2010 May;105(10):1417-22. Review.
  • Wo JY, Taghian AG, Nguyen PL, Raad RA, Sreedhara M, Bellon JR, Wong JS, Gadd MA, Smith BL, Harris JR.The Association Between Biological Subtype and Isolated Regional Nodal Failure After Breast-Conserving Therapy.Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):188-96.
  • Choueiri TK, Chen MH, D'Amico AV, Sun L, Nguyen PL, Hayes JH, Robertson CN, Walther PJ, Polascik TJ, Albala DM, Moul JW.Impact of postoperative prostate-specific antigen disease recurrence and the use of salvage therapy on the risk of death.Cancer. 2010 Apr 15;116(8):1887-92.
  • Hoffman KE, Nguyen PL, Ng AK, D'Amico AV.Prostate Cancer Screening in Men 75 Years Old or Older: An Assessment of Self-Reported Health Status and Life Expectancy.J Urol. 2010 May;183(5):1798-802.
  • Flavin R, Peluso S, Nguyen PL, Loda M.Fatty acid synthase as a potential therapeutic target in cancer.Future Oncol. 2010 Apr;6(4):551-62. Review.
  • Nguyen PL.Editorial Comment.J Urol. 2010 Mar;183(3):989.
  • Nguyen PL,Chen MH,Renshaw AA,Loffredo M,Kantoff PW,D'Amico AV.Survival Following Radiation and Androgen Suppression Therapy for Prostate Cancer in Healthy Older Men: Implications for Screening Recommendations.Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):337-41.
  • Nguyen PL, Chen MH, Beard CJ, Suh WW, Choueiri TK, Efstathiou JA, Hoffman KE, Loffredo M, Kantoff PW, D'Amico AV.Comorbidity, body mass index, and age and the risk of nonprostate-cancer-specific mortality after a postradiation prostate-specific antigen recurrence.Cancer. 2010 Feb 1;116(3):610-5.
  • Wo JY, Chen MH, Nguyen PL, Renshaw AA, Loffredo MJ, Kantoff PW, D'Amico AV.Evaluating the Combined Effect of Comorbidity and Prostate-Specific Antigen Kinetics on the Risk of Death in Men After Prostate-Specific Antigen Recurrence.J Clin Oncol. 2009 Dec 10;27(35):6000-5.
  • Nguyen PL,Chen RC,Clark JA,Cormack RA,Loffredo M,McMahon E,Nguyen AU,Suh WW,Tempany CM,D'Amico AV.Patient-reported quality of life after salvage brachytherapy for radio-recurrent prostate cancer: A prospective Phase II study.Brachytherapy.;8(4):345-52.
  • Nguyen PL,Lin DI,Lei J,Fiorentino M,Mueller E,Weinstein MH,Pagano M,Loda M.The impact of Skp2 overexpression on recurrence-free survival following radical prostatectomy.Urol Oncol. 2009 May 16.
  • Nguyen PL,Chen MH,Hoffman KE,Katz MS,D'Amico AV.Predicting the risk of pelvic node involvement among men with prostate cancer in the contemporary era.Int J Radiat Oncol Biol Phys. 2009 May 1;74(1):104-9.
  • Nguyen PL,Chen MH,Catalona WJ,Alexander BM,Roehl KA,Loeb S,D'Amico AV.Biochemical recurrence after radical prostatectomy for prevalent versus incident cases of prostate cancer : implications for management.Cancer. 2008 Dec 1;113(11):3146-52.
  • Fiorentino M,Zadra G,Palescandolo E,Fedele G,Bailey D,Fiore C,Nguyen PL,Migita T,Zamponi R,Di Vizio D,Priolo C,Sharma C,Xie W,Hemler ME,Mucci L,Giovannucci E,Finn S,Loda M.Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer.Lab Invest. 2008 Dec;88(12):1340-8.
  • Ma J,Li H,Giovannucci E,Mucci L,Qiu W,Nguyen PL,Gaziano JM,Pollak M,Stampfer MJ.Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis.Lancet Oncol. 2008 Nov;9(11):1039-47.
  • Nguyen PL,Chen MH,Catalona WJ,Moul JW,Sun L,D'Amico AV.Predicting prostate cancer mortality among men with intermediate to high-risk disease and multiple unfavorable risk factors.Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):659-64.
  • Nguyen PL,Trofimov A,Zietman AL.Proton-beam vs intensity-modulated radiation therapy. Which is best for treating prostate cancer?.Oncology (Huntingt). 2008 Jun;22(7):748-54; discussion 754, 757. Review.
  • Nguyen PL, D'Amico AV.Targeting pelvic lymph nodes in men with intermediate- and high-risk prostate cancer despite two negative randomized trials.J Clin Oncol. 2008 Apr 20;26(12):2055-6; author reply 2056-7.
  • Nguyen PL, Taghian AG, Katz MS, Niemierko A, Abi Raad RF, Boon WL, Bellon JR, Wong JS, Smith BL, Harris JR.Breast cancer subtype approximated by estrogen receptor, progesterone receptor, and HER-2 is associated with local and distant recurrence after breast-conserving therapy.J Clin Oncol. 2008 May 10;26(14):2373-8.
  • Nguyen PL, Zietman AL.High-dose external beam radiation for localized prostate cancer: current status and future challenges.Cancer J. 2007 Sep-Oct;13(5):295-301. Review.
  • Nguyen PL, Chen MH, Renshaw AA, Sussman B, D'Amico AV.Effect of definition of preradiotherapy prostate-specific antigen velocity on its association with prostate cancer-specific mortality and all-cause mortality.Urology. 2007 Aug;70(2):288-93.
  • Nguyen PL, Chen MH, D'Amico AV, Tempany CM, Steele GS, Albert M, Cormack RA, Carr-Locke DL, Bleday R, Suh WW.Magnetic resonance image-guided salvage brachytherapy after radiation in select men who initially presented with favorable-risk prostate cancer: a prospective phase 2 study.Cancer. 2007 Oct 1;110(7):1485-92.
  • Nguyen PL,D'Amico AV,Lee AK,Suh WW.Patient selection, cancer control, and complications after salvage local therapy for postradiation prostate-specific antigen failure: a systematic review of the literature.Cancer. 2007 Oct 1;110(7):1417-28.
  • Trofimov A, Nguyen PL, Coen JJ, Doppke KP, Schneider RJ, Adams JA, Bortfeld TR, Zietman AL, Delaney TF, Shipley WU.Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: a treatment planning comparison.Int J Radiat Oncol Biol Phys. 2007 Oct 1;69(2):444-53.
  • Nguyen PL, Whittington R, Koo S, Schultz D, Cote KB, Loffredo M, McMahon E, Renshaw AA, Tomaszewski JE, D'Amico AV.The impact of a delay in initiating radiation therapy on prostate-specific antigen outcome for patients with clinically localized prostate carcinoma.Cancer. 2005 May 15;103(10):2053-9.
  • Nguyen PL, Chakravarti A, Finkelstein DM, Hochberg FH, Batchelor TT, Loeffler JS.Results of whole-brain radiation as salvage of methotrexate failure for immunocompetent patients with primary CNS lymphoma.J Clin Oncol. 2005 Mar 1;23(7):1507-13.
  • Nguyen PL, Schultz D, Renshaw AA, Vollmer RT, Welch WR, Cote K, D'Amico AV.The impact of pathology review on treatment recommendations for patients with adenocarcinoma of the prostate.Urol Oncol.;22(4):295-9.
  • Koo S, Kucher N, Nguyen PL, Fanikos J, Marks PW, Goldhaber SZ.The effect of excessive anticoagulation on mortality and morbidity in hospitalized patients with anticoagulant-related major hemorrhage.Arch Intern Med. 2004 Jul 26;164(14):1557-60.
  • Nguyen PL, Whittington R, Koo S, Schultz D, Cote KB, Loffredo M, Tempany CM, Titelbaum DS, Schnall MD, Renshaw AA, Tomaszewski JE, D'Amico AV.Quantifying the impact of seminal vesicle invasion identified using endorectal magnetic resonance imaging on PSA outcome after radiation therapy for patients with clinically localized prostate cancer.Int J Radiat Oncol Biol Phys. 2004 Jun 1;59(2):400-5.