Rachael A. Clark, MD, PhD

Publications

• Clark RA, Shackelton JB, Watanabe R, Calarese A, Yamanaka K, Campbell JJ, Teague JE, Kuo HP, Hijnen D, Kupper TS.High-scatter T cells: a reliable biomarker for malignant T cells in cutaneous T-cell lymphoma.Blood. 2011 Feb 10;117(6):1966-76.
  21148332
• Trimble CL, Clark RA, Thoburn C, Hanson NC, Tassello J, Frosina D, Kos F, Teague J, Jiang Y, Barat NC, Jungbluth AA.Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium.J Immunol.
  21037100
• de Jong A, Peña-Cruz V, Cheng TY, Clark RA, Van Rhijn I, Moody DB.CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire.Nat Immunol. 2010 Dec;11(12):1102-9.
  21037579
• Cedeno-Laurent F, Barthel SR, Opperman MJ, Lee DM, Clark RA, Dimitroff CJ.Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation.J Immunol. 2010 Oct 15;185(8):4659-72.
  20844192
• Campbell JJ, Clark RA, Watanabe R, Kupper TS.Sezary syndrome and MF arise from distinct T cell subsets: a biologic rationale for their distinct clinical behaviors.Blood. 2010 Aug 5;116(5):767-71.
  20484084
• van Geel NA, Mollet IG, De Schepper S, Tjin EP, Vermaelen K, Clark RA, Kupper TS, Luiten RM, Lambert J.First histopathological and immunophenotypic analysis of early dynamic events in a patient with segmental vitiligo associated with halo nevi.Pigment Cel
  20370855
• Clark RA.Skin-resident T cells: the ups and downs of on site immunity.J Invest Dermatol. 2010 Feb;130(2):362-70. Review.
  19675575
• Clark RA.Regulation gone wrong: a subset of Sézary patients have malignant regulatory T cells.J Invest Dermatol. 2009 Dec;129(12):2747-50.
  19901946
• Huang SJ, Hijnen D, Murphy GF, Kupper TS, Calarese AW, Mollet IG, Schanbacher CF, Miller DM, Schmults CD, Clark RA.Imiquimod Enhances IFN-gamma Production and Effector Function of T Cells Infiltrating Human Squamous Cell Carcinomas of the Skin.J Invest De
  19516264
• Clark RA, Fuhlbrigge RC.Immunology and skin disease 2009: frontiers in cutaneous immunology.J Invest Dermatol. 2009 Aug;129(8):1849-51.
  19603049
• Clark RA,Huang SJ,Murphy GF,Mollet IG,Hijnen D,Muthukuru M,Schanbacher CF,Edwards V,Miller DM,Kim JE,Lambert J,Kupper TS.Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cel
  18794336
• Clark RA, Kupper TS.IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin.Blood. 2007 Jan 1;109(1):194-202.
  16968902
• Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS.The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors.J Immunol. 2006 Oct 1;177(7):4488-94.
  16982885
• Clark RA, Chong BF, Mirchandani N, Yamanaka K, Murphy GF, Dowgiert RK, Kupper TS.A novel method for the isolation of skin resident T cells from normal and diseased human skin.J Invest Dermatol. 2006 May;126(5):1059-70.
  16484986
• Clark RA, Chong B, Mirchandani N, Brinster NK, Yamanaka K, Dowgiert RK, Kupper TS.The vast majority of CLA+ T cells are resident in normal skin.J Immunol. 2006 Apr 1;176(7):4431-9.
  16547281