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Akash Patnaik, MD, PhD


  • Gonz├ílez-Billalabeitia E, Seitzer N, Song SJ, Song MS, Patnaik A, Liu XS, Epping MT, Papa A, Hobbs RM, Chen M, Lunardi A, Ng C, Webster KA, Signoretti S, Loda M, Asara JM, Nardella C, Clohessy JG, Cantley LC, Pandolfi PP.Vulnerabilities of PTEN-p53-deficient prostate cancers to compound PARP/PI3K inhibition.Cancer Discovery. 2014 May 27.
  • Fendt SM, Bell EL, Keibler MA, Davidson SM, Wirth GJ, Fiske B, Mayers JR, Schwab M, Bellinger G, Csibi A, Patnaik A, Blouin MJ, Cantley LC, Guarente L, Blenis J, Pollak MN, Olumi AF, Vander Heiden MG, Stephanopoulos G.Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.Cancer Res. 2013 Jul 15;73(14):4429-38.
  • Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph RW, Weber JS, Dronca R, Gangadhar TC, Patnaik A, Zarour H, Joshua AM, Gergich K, Elassaiss-Schaap J, Algazi A, Mateus C, Boasberg P, Tumeh PC, Chmielowski B, Ebbinghaus SW, Li XN, Kang SP, Ribas A.Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma.N Engl J Med. 2013 Jul 11;369(2):134-44.
  • Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, Gerald WL, Montironi R, Signoretti S, Loda M, Nardella C, Pandolfi PP.A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.Nat Genet. 2013 Jul;45(7):747-55.
  • Zadra G, Priolo C, Patnaik A, Loda M.New Strategies in Prostate Cancer: Targeting Lipogenic Pathways and the Energy Sensor AMPK.Clin Cancer Res. 2010 Jul 1;16(13):3322-8. Review.
  • Shaywitz AJ,Courtney KD,Patnaik A,Cantley LC.PI3K enters beta-testing.Cell Metab. 2008 Sep;8(3):179-81. Review.
  • Spidel JL, Craven RC, Wilson CB, Patnaik A, Wang H, Mansky LM, Wills JW.Lysines close to the Rous sarcoma virus late domain critical for budding.J Virol. 2004 Oct;78(19):10606-16.
  • Patnaik A, Chau V, Li F, Montelaro RC, Wills JW.Budding of equine infectious anemia virus is insensitive to proteasome inhibitors.J Virol. 2002 Mar;76(6):2641-7.
  • Patnaik A, Wills JW.In vivo interference of Rous sarcoma virus budding by cis expression of a WW domain.J Virol. 2002 Mar;76(6):2789-95.
  • Patnaik A, Chau V, Wills, JW.Ubiquitin is a component of the retrovirus budding machinery.Proc Natl Acad Sci U S A.;97:13069-74.