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Miguel N. Rivera, MD

Publications

  • Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE.Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.Cell. 2014 Apr 24;157(3):580-94.
    24726434
  • Faber AC, Coffee EM, Costa C, Dastur A, Ebi H, Hata AN, Yeo AT, Edelman EJ, Song Y, Tam AT, Boisvert JL, Milano RJ, Roper J, Kodack DP, Jain RK, Corcoran RB, Rivera MN, Ramaswamy S, Hung KE, Benes CH, Engelman JA.mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.Cancer Discovery. 2014 Jan;4(1):42-52.
    24163374
  • Liu M, Roth A, Yu M, Morris R, Bersani F, Rivera MN, Lu J, Shioda T, Vasudevan S, Ramaswamy S, Maheswaran S, Diederichs S, Haber DA.The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis.Genes Dev. 2013 Dec 1;27(23):2543-8.
    24298054
  • Akhavanfard S, Vargas SO, Han M, Nitta M, Chang CB, Le LP, Fazlollahi L, Nguyen Q, Ma Y, Cosper A, Dias-Santagata D, Han JY, Bergethon K, Borger DR, Ellisen LW, Pomeroy SL, Haber DA, Iafrate AJ, Rivera MN.Inactivation of the tumor suppressor WTX in a subset of pediatric tumors.Genes Chromosomes Cancer. 2014 Jan;53(1):67-77.
    24249259
  • Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE.An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.Cell Rep. 2013 May 30;3(5):1567-79.
    23707066
  • Crompton BD, Carlton AL, Thorner AR, Christie AL, Du J, Calicchio ML, Rivera MN, Fleming MD, Kohl NE, Kung AL, Stegmaier K.High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma.Cancer Res. 2013 Apr 22.
    23536552
  • Moisan A, Rivera MN, Lotinun S, Akhavanfard S, Coffman EJ, Cook EB, Stoykova S, Mukherjee S, Schoonmaker JA, Burger A, Kim WJ, Kronenberg HM, Baron R, Haber DA, Bardeesy N.The WTX Tumor Suppressor Regulates Mesenchymal Progenitor Cell Fate Specification.Dev Cell. 2011 May 17;20(5):583-96.
    21571217
  • Ting DT, Lipson D, Paul S, Brannigan BW, Akhavanfard S, Coffman EJ, Contino G, Deshpande V, Iafrate AJ, Letovsky S, Rivera MN, Bardeesy N, Maheswaran S, Haber DA.Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers.Science. 2011 Feb 4;331(6017):593-6.
    21233348
  • Wells J, Rivera MN, Kim WJ, Starbuck K, Haber DA.The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Mol Cancer Res. 2010 Jul;8(7):975-85.
    20571064
  • Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE.Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.Cell Stem Cell. 2010 Jun 4;6(6):591-602.
    20569696
  • Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA.A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.Cancer Res. 2010 Mar 15;70(6):2158-64.
    20215515
  • Rivera MN,Kim WJ,Wells J,Stone A,Burger A,Coffman EJ,Zhang J,Haber DA.The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity.Proc Natl Acad Sci U S A. 2009 May 19;106(20):8338-43.
    19416806
  • Godin-Heymann N, Bryant I, Rivera MN, Ulkus L, Bell DW, Riese DJ, Settleman J, Haber DA.Oncogenic activity of epidermal growth factor receptor kinase mutant alleles is enhanced by the T790M drug resistance mutation.Cancer Res. 2007 Aug 1;67(15):7319-26.
    17671201
  • Rivera MN, Kim WJ, Wells J, Driscoll DR, Brannigan BW, Han M, Kim JC, Feinberg AP, Gerald WL, Vargas SO, Chin L, Iafrate AJ, Bell DW, Haber DA.An X chromosome gene, WTX, is commonly inactivated in Wilms tumor.Science. 2007 Feb 2;315(5812):642-5.
    17204608
  • Rivera MN, Haber DA.Wilms' tumour: connecting tumorigenesis and organ development in the kidney.Nat Rev Cancer. 2005 Sep;5(9):699-712. Review.
    16110318