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Sung-Yun Pai MD


  • Leen AM, Bollard CM, Mendizabal AM, Shpall EJ, Szabolcs P, Antin JH, Kapoor N, Pai SY, Rowley SD, Kebriaei P, Dey BR, Grilley BJ, Gee AP, Brenner MK, Rooney CM, Heslop HE.Multicenter study of banked third party virus-specific T-cells to treat severe viral infections after hematopoietic stem cell transplantation.Blood. 2013 Apr 22.
  • Cattaneo F, Recher M, Masneri S, Baxi SN, Fiorini C, Antonelli F, Wysocki CA, Calderon JG, Eibel H, Smith AR, Bonilla FA, Tsitsikov E, Giliani S, Notarangelo LD, Pai SY.Hypomorphic Janus kinase 3 mutations result in a spectrum of immune defects, including partial maternal T-cell engraftment.J Allergy Clin Immunol. 2013 Apr;131(4):1136-45.
  • Tai TS, Pai SY, Ho IC.GATA-3 regulates the homeostasis and activation of CD8+ T cells.J Immunol. 2013 Jan 1;190(1):428-37.
  • Kohn DB, Pai SY, Sadelain M.Gene Therapy through Autologous Transplantation of Gene-Modified Hematopoietic Stem Cells.Biol Blood Marrow Transplant. 2012 Sep 29.
  • Henderson LA, Frugoni F, Hopkins G, Al-Herz W, Weinacht K, Comeau AM, Bonilla FA, Notarangelo LD, Pai SY.First reported case of Omenn syndrome in a patient with reticular dysgenesis.J Allergy Clin Immunol. 2012 Sep 23.
  • McDonald DR, Massaad MJ, Johnston A, Keles S, Chatila T, Geha RS, Pai SY.Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency.J Allergy Clin Immunol. 2010 Dec;126(6):1304-5.e3.
  • Debelenko L, Perez-Atayde AR, Du-Bois SG, Grier HE, Pai SY, Shamberger RC, Kozakewich HP.p53(+)/mdm2(-) Atypical Lipomatous Tumor/Well Differentiated Liposarcoma in Young Children: an Early Expression of Li-Fraumeni Syndrome.Pediatr Dev Pathol.;13(3):218-24.
  • Pai SY, Notarangelo LD.Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: advances in biology and future directions for treatment.Immunol Allergy Clin North Am. 2010 May;30(2):179-94. Review.
  • Hattori H, Subramanian KK, Sakai J, Jia Y, Li Y, Porter TF, Loison F, Sarraj B, Kasorn A, Jo H, Blanchard C, Zirkle D, McDonald D, Pai SY, Serhan CN, Luo HR.Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3546-51.
  • Pei XH, Bai F, Smith MD, Usary J, Fan C, Pai SY, Ho IC, Perou CM, Xiong Y.CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis.Cancer Cell. 2009 May 5;15(5):389-401.
  • Sheehan WJ, Delmonte OM, Miller DT, Roberts AE, Bonilla FA, Morra M, Giliani S, Pai SY, Notarangelo LD, Oettgen HC.Novel presentation of Omenn syndrome in association with aniridia.J Allergy Clin Immunol. 2009 Apr;123(4):966-9.
  • Permaul P,Narla A,Hornick JL,Pai SY.Allogeneic hematopoietic stem cell transplantation for X-linked ectodermal dysplasia and immunodeficiency: case report and review of outcomes.Immunol Res. 2009;44(1-3):89-98. Review.
  • Ho IC, Tai TS, Pai SY.GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation.Nat Rev Immunol. 2009 Feb;9(2):125-35. Review.
  • Pai SY,Levy O,Jabara HH,Glickman JN,Stoler-Barak L,Sachs J,Nurko S,Orange JS,Geha RS.Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency.J Allergy Clin Immunol. 2008 Dec;122(6):1113-1118.e1.
  • Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z.GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.Cancer Cell. 2008 Feb;13(2):141-52.
  • Pai SY, Kang BY, Sabadini AM, Parisini E, Truitt ML, Ho IC.Distinct structural requirements of GATA-3 for the regulation of thymocyte and Th2 cell differentiation.J Immunol. 2008 Jan 15;180(2):1050-9.
  • Ho IC, Pai SY.GATA-3 - not just for Th2 cells anymore.Cell Mol Immunol. 2007 Feb;4(1):15-29. Review.
  • de Guzman Strong C, Wertz PW, Wang C, Yang F, Meltzer PS, Andl T, Millar SE, Ho IC, Pai SY, Segre JA.Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3.J Cell Biol. 2006 Nov 20;175(4):661-70.
  • Kim PJ, Pai SY, Brigl M, Besra GS, Gumperz J, Ho IC.GATA-3 regulates the development and function of invariant NKT cells.J Immunol. 2006 Nov 15;177(10):6650-9.
  • Pai SY, Truitt ML, Ho IC.GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells.Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1993-8.
  • Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC.Critical roles for transcription factor GATA-3 in thymocyte development.Immunity. 2003 Dec;19(6):863-75.