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Peter M. Sadow, MD, PhD

Publications

  • Pusztaszeri MP, Sadow PM, Faquin WC.CD117: A novel ancillary marker for papillary thyroid carcinoma in fine-needle aspiration biopsies.Cancer Cytopathol. 2014 Jun 11.
    24920192
  • McFadden DG, Vernon A, Santiago PM, Martinez-McFaline R, Bhutkar A, Crowley DM, McMahon M, Sadow PM, Jacks T.p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer.Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1600-9.
    24711431
  • Lubitz CC, Economopoulos KP, Pawlak AC, Lynch K, Dias-Santagata D, Faquin WC, Sadow PM.Hobnail Variant of Papillary Thyroid Carcinoma: An Institutional Case Series and Molecular Profile.Thyroid. 2014 Jan 13.
    24417340
  • Gray ST, Herr MW, Sethi RK, Diercks G, Lee L, Curry W, Chan A, Clark J, Holbrook EH, Rocco J, Sadow PM, Lin DT.Treatment outcomes and prognostic factors including human papillomavirus (HPV) for sinonasal undifferentiated carcinoma: A retrospective review.Head Neck. 2014 Jan 13.
    24421248
  • Duquette M, Sadow PM, Lawler J, Nucera C.Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells with BRAF(V600E): New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment.Front Endocrinol (Lausanne). 2013;4:189.
    24348463
  • Pusztaszeri MP, Sadow PM, Ushiku A, Bordignon P, McKee TA, Faquin WC.MYB immunostaining is a useful ancillary test for distinguishing adenoid cystic carcinoma from pleomorphic adenoma in fine-needle aspiration biopsy specimens.Cancer Cytopathol. 2013 Dec 2.
    24302647
  • Vanden Borre P, McFadden DG, Gunda V, Sadow PM, Varmeh S, Bernasconi MJ, Jacks T, Parangi S.The Next Generation of Orthotopic Thyroid Cancer Models: Immunocompetent Orthotopic Mouse Models of BRAFV600E-Positive Papillary and Anaplastic Thyroid Carcinoma.Thyroid. 2013 Dec 2.
    24295207
  • Remenschneider AK, Sadow PM, Lin DT, Gray ST.Metastatic renal cell carcinoma to the sinonasal cavity: a case series.J Neurol Surg Rep. 2013 Dec;74(2):67-72.
    24294563
  • Farhat NA, Faquin WC, Sadow PM.Primary mucoepidermoid carcinoma of the thyroid gland: a report of three cases and review of the literature.Endocr Pathol. 2013 Dec;24(4):229-33.
    24096806
  • Linskey KR, Gimbel DC, Zukerberg LR, Duncan LM, Sadow PM, Nazarian RM.BerEp4, cytokeratin 14, and cytokeratin 17 immunohistochemical staining aid in differentiation of basaloid squamous cell carcinoma from basal cell carcinoma with squamous metaplasia.Arch Pathol Lab Med. 2013 Nov;137(11):1591-8.
    24168496
  • Infusino SA, Ojha S, Maurer R, Sadow PM, Faquin WC, Hartnick CJ.The utility of histopathology in identifying structural differences among layers of the lamina propria.Int. J. Pediatr. Otorhinolaryngol. 2013 Oct;77(10):1651-4.
    24001615
  • Mason EF, Sadow PM, Wagner AJ, Remillard SP, Flood TA, Belanger EC, Hornick JL, Barletta JA.Identification of succinate dehydrogenase-deficient bladder paragangliomas.Am J Surg Pathol. 2013 Oct;37(10):1612-8.
    23797725
  • Feldman RE, Lam AC, Sadow PM, Bleier BS.P-glycoprotein is a marker of tissue eosinophilia and radiographic inflammation in chronic rhinosinusitis without nasal polyps.Int Forum Allergy Rhinol. 2013 Aug;3(8):684-7.
    23677641
  • He W, Cheville JC, Sadow PM, Gopalan A, Fine SW, Al-Ahmadie HA, Chen YB, Oliva E, Russo P, Reuter VE, Tickoo SK.Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors.Mod Pathol. 2013 Apr 19.
    23599151
  • Pusztaszeri MP, Sadow PM, Faquin WC.Images in Endocrine Pathology: Psammomatoid Calcifications in Oncocytic Neoplasms of the Thyroid, a Potential Pitfall for Papillary Carcinoma.Endocr Pathol. 2013 Apr 16.
    23589120
  • Diercks GR, Iannuzzi RA, McCowen K, Sadow PM.Dermoid Cyst of the Lateral Neck Associated with the Thyroid Gland: a Case Report and Review of the Literature.Endocr Pathol. 2013 Feb 17.
    23417694
  • Wirth LJ, Ross DS, Randolph GW, Cunnane ME, Sadow PM.Case records of the Massachusetts General Hospital. Case 5-2013. A 52-year-old woman with a mass in the thyroid.N Engl J Med. 2013 Feb 14;368(7):664-73.
    23406032
  • Nardi V, Sadow PM, Juric D, Zhao D, Cosper AK, Bergethon K, Scialabba VL, Batten JM, Borger DR, Iafrate AJ, Heist RS, Lawrence DP, Flaherty KT, Bendell JC, Deschler D, Li Y, Wirth LJ, Dias-Santagata D.Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment.Clin Cancer Res. 2013 Jan 15;19(2):480-90.
    23186780
  • Stankovic KM, Eskandar E, El Khoury JB, Lev MH, Sadow PM.Case records of the Massachusetts General Hospital. Case 2-2013. A 20-year-old man with recurrent ear pain, fever, and headache.N Engl J Med. 2013 Jan 17;368(3):267-77.
    23323904
  • Wu AW, Ting JY, Borgie RC, Busaba NY, Sadow PM, Juliano AF, Gray ST, Holbrook EH.Diagnostic characteristics of sinonasal organizing hematomas: avoiding misdiagnosis.Int Forum Allergy Rhinol. 2013 Jan 10.
    23307434
  • Prescott JD, Sadow PM, Hodin RA, Le LP, Gaz RD, Randolph GW, Stephen AE, Parangi S, Daniels GH, Lubitz CC.BRAF V600E status adds incremental value to current risk classification systems in predicting papillary thyroid carcinoma recurrence.Surgery. 2012 Dec;152(6):984-90.
    23158172
  • Guthrie D, Peacock ZS, Sadow P, Dodson TB, August M.Preoperative incisional and intraoperative frozen section biopsy techniques have comparable accuracy in the diagnosis of benign intraosseous jaw pathology.J Oral Maxillofac Surg. 2012 Nov;70(11):2566-72.
    22285333
  • Pusztaszeri MP, Sadow PM, Faquin WC.Association of CD1a-positive dendritic cells with papillary thyroid carcinoma in thyroid fine-needle aspirations: A cytologic and immunocytochemical evaluation.Cancer Cytopathol. 2012 Oct 5.
    23042745
  • Bellelli R, Castellone MD, Garcia-Rostan G, Ugolini C, Nucera C, Sadow PM, Nappi TC, Salerno P, Cantisani MC, Basolo F, Gago TA, Salvatore G, Santoro M.FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.Endocr. Relat. Cancer. 2012 Oct;19(5):695-710.
    22919068
  • Bledsoe JR, Sadow PM, Stephen A, Nielsen GP, Faquin WC.Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features.Endocr Pathol. 2012 Sep;23(3):177-80.
    22527948
  • Bleier BS, Feldman R, Sadow PM, Wu A, Ting J, Metson R.The accessory posterolateral nerve: an immunohistological analysis.Am J Rhinol Allergy.;26(4):271-3.
    22801012
  • Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, Lawler J, Wei W.SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2.J Exp Med. 2012 Jul 2;209(7):1289-307.
    22711876
  • Sadow PM, Faquin WC.Poorly differentiated thyroid carcinoma: an incubating entity.Front Endocrinol (Lausanne). 2012;3:77.
    22737144
  • Gray ST, Holbrook EH, Najm MH, Sadow PM, Curry WT, Lin DT.Syndrome of Inappropriate Antidiuretic Hormone Secretion in Patients with Olfactory Neuroblastoma.Otolaryngology Head And Neck Surgery : Official Journal Of American Academy Of Otolaryngology Head And Neck Surgery. 2012 Feb 24.
    22368044
  • Nehs MA, Nucera C, Nagarkatti SS, Sadow PM, Morales-Garcia D, Hodin RA, Parangi S.Late intervention with anti-BRAF(V600E) therapy induces tumor regression in an orthotopic mouse model of human anaplastic thyroid cancer.Endocrinology. 2012 Feb;153(2):985-94.
    22202162
  • Hill CA, Gallagher TQ, Maturo S, Sadow PM, Curtin HD, Hartnick CJ.Radiology quiz case 1. Congenital cyst of the newborn.Arch. Otolaryngol. Head Neck Surg. 2012 Jan;138(1):87-9.
    22249637
  • Pellicer DL, Sadow PM, Stephen A, Faquin WC.Atypical squamous metaplasia in a benign cystic thyroid nodule mimicking high-grade carcinoma.Diagn Cytopathol. 2011 Dec 5.
    22144088
  • Yip DT, Hassan M, Pazaitou-Panayiotou K, Ruan DT, Gawande AA, Gaz RD, Moore FD, Hodin RA, Stephen AE, Sadow PM, Daniels GH, Randolph GW, Parangi S, Lubitz CC.Preoperative basal calcitonin and tumor stage correlate with postoperative calcitonin normalization in patients undergoing initial surgical management of medullary thyroid carcinoma.Surgery. 2011 Dec;150(6):1168-77.
    22136837
  • Faquin WC, Bongiovanni M, Sadow PM.Update in Thyroid Fine Needle Aspiration.Endocr Pathol. 2011 Oct 14.
    21997833
  • Sedaghat AR, Gallagher TQ, Sadow PM, Cunnane ME, Cunningham MJ.Radiology quiz case 2.Arch. Otolaryngol. Head Neck Surg. 2011 Sep;137(9):955.
    21930990
  • Paul E, Thiele EA, Shailam R, Rosales AM, Sadow PM.Case records of the Massachusetts General Hospital. Case 26-2011. A 7-year-old boy with a complex cyst in the kidney.N Engl J Med. 2011 Aug 25;365(8):743-51.
    21864169
  • Phitayakorn R, Maclennan G, Sadow P, Wilhelm S.Adrenal adenomatoid tumor in a patient with human immunodeficiency virus.Rare Tumors. 2011 Apr 4;3(2):e21.
    21769320
  • Courville EL, Lew M, Sadow PM.Routine Evaluation of Adult Tonsillectomy Specimens: Toward Establishing a New Standard of Care.Int J Surg Pathol. 2011 Mar 21.
    21427094
  • Nucera C, Nehs MA, Nagarkatti SS, Sadow PM, Mekel M, Fischer AH, Lin PS, Bollag GE, Lawler J, Hodin RA, Parangi S.Targeting BRAFV600E with PLX4720 Displays Potent Antimigratory and Anti-invasive Activity in Preclinical Models of Human Thyroid Cancer.Oncologist. 2011;16(3):296-309.
    21355020
  • Hammon RJ, Lin HW, Sadow PM, Lin DT, Rocco JW.Pathology quiz case 1.Arch. Otolaryngol. Head Neck Surg. 2011 Feb;137(2):198.
    21339411
  • Lin HW, Silver AL, Cunnane ME, Sadow PM, Kieff DA.Lateral dermoid cyst of the floor of mouth: Unusual radiologic and pathologic findings.Auris Nasus Larynx. 2011 Feb 17.
    21334151
  • Kakarala K, Sadow PM, Emerick KS.Cervical lymph node collision tumor consisting of metastatic squamous cell carcinoma and B-cell lymphoma.Laryngoscope. 2010;120 Suppl 4:S156. Review.
    21225754
  • Cabot RC, Harris NL, Shepard JA, Rosenberg ES, Cort AM, Ebeling SH, Peters CC, Misra M, Parangi S, Ross DS, Shailam R, Sadow PM.Case records of the Massachusetts General Hospital: Case 38-2010: a 13-year-old girl with an enlarging neck mass.N Engl J Med. 2010 Dec 16;363(25):2445-54.
    21158661
  • Cleary JM, Sadow PM, Randolph GW, Palmer EL, Lynch TP, Nikiforov YE, Wirth LJ.Neoadjuvant treatment of unresectable medullary thyroid cancer with sunitinib.J Clin Oncol. 2010 Aug 10;28(23):e390-2.
    20567012
  • Sadow PM, Hunt JL.Mixed Medullary-follicular-derived carcinomas of the thyroid gland.Adv Anat Pathol. 2010 Jul;17(4):282-5. Review.
    20574174
  • Samuels MA, Pomerantz BJ, Sadow PM.Case records of the Massachusetts General Hospital. Case 14-2010. A 54-year-old woman with dizziness and falls.N Engl J Med. 2010 May 13;362(19):1815-23.
    20463342
  • Leleiko NS, Gee MS, Sadow PM.Case records of the Massachusetts General Hospital. Case 13-2010. An 18.5-month-old girl with watery diarrhea and poor weight gain.N Engl J Med. 2010 Apr 29;362(17):1619-26.
    20427811
  • Sadow PM, Heinrich MC, Corless CL, Fletcher JA, Nosé V.Absence of BRAF, NRAS, KRAS, HRAS Mutations, and RET/PTC Gene Rearrangements Distinguishes Dominant Nodules in Hashimoto Thyroiditis from Papillary Thyroid Carcinomas.Endocr Pathol. 2010 Jun;21(2):73-9.
    20012784
  • Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA.A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.Cancer Res. 2010 Mar 15;70(6):2158-64.
    20215515
  • Bongiovanni M, Sadow PM, Faquin WC.Poorly differentiated thyroid carcinoma: a cytologic-histologic review.Adv Anat Pathol. 2009 Sep;16(5):283-9. Review.
    19700938
  • Ibaragi S,Yoshioka N,Li S,Hu MG,Hirukawa S,Sadow PM,Hu GF.Neamine inhibits prostate cancer growth by suppressing angiogenin-mediated rRNA transcription.Clin Cancer Res. 2009 Mar 15;15(6):1981-8.
    19276260
  • Ibaragi S,Yoshioka N,Kishikawa H,Hu JK,Sadow PM,Li M,Hu GF.Angiogenin-stimulated rRNA transcription is essential for initiation and survival of AKT-induced prostate intraepithelial neoplasia.Mol Cancer Res. 2009 Mar;7(3):415-24.
    19258415
  • Lowenthal MS, Sadow PM, Raut C, Metzler EC.Intraoperative diagnosis of a functional paraganglioma presenting as a gastrointestinal stromal cell tumor (GIST).J Clin Anesth. 2009 Feb;21(1):57-60.
    19232943
  • Lee JM,Pou K,Sadow PM,Chen H,Hu B,Hewison M,Adams JS,Sugarbaker DJ,Fisher ND.Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma.Endocr Pract. 2008 Nov;14(8):1011-6.
    19095601
  • Jain SH, Sadow PM, Nosé V, Dluhy RG, .A patient with ectopic cortisol production derived from malignant testicular masses.Nat Clin Pract Endocrinol Metab. 2008 Dec;4(12):695-700.
    18941436
  • Sadow PM, Rumilla KM, Erickson LA, Lloyd RV.Stathmin expression in pheochromocytomas, paragangliomas, and in other endocrine tumors.Endocr Pathol. 2008;19(2):97-103.
    18461287
  • Yassa L, Sadow P, Marqusee E.Malignant struma ovarii.Nat Clin Pract Endocrinol Metab. 2008 Aug;4(8):469-72.
    18560398
  • Kohler JE, Hutchens MP, Sadow PM, Modi BP, Tavakkolizadeh A, Gates JD.Klebsiella pneumoniae necrotizing fasciitis and septic arthritis: an appearance in the Western hemisphere.Surg Infect (Larchmt). 2007 Apr;8(2):227-32. Review.
    17437368
  • Benacerraf BR, Sadow PM, Barnewolt CE, Estroff JA, Benson C.Cleft of the secondary palate without cleft lip diagnosed with three-dimensional ultrasound and magnetic resonance imaging in a fetus with Fryns' syndrome.Ultrasound Obstet Gynecol. 2006 May;27(5):566-70.
    16619385
  • Wu SY, Sadow PM, Refetoff S, Weiss RE.Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T).J. Lab. Clin. Med. 2005 Aug;146(2):85-94.
    16099238
  • Jung JC, West-Mays JA, Stramer BM, Byrne MH, Scott S, Mody MK, Sadow PM, Krane SM, Fini ME.Activity and expression of Xenopus laevis matrix metalloproteinases: identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals.J Cell Physiol. 2004 Oct;201(1):155-64.
    15281098
  • Sadow PM, Chassande O, Koo EK, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE.Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone.Mol Cell Endocrinol. 2003 May 30;203(1-2):65-75.
    12782404
  • Sadow PM, Koo E, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Seo H, Murata Y, Weiss RE.Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary.Mol Endocrinol. 2003 May;17(5):882-94.
    12576486
  • Sadow PM, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE.Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action.Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E36-46.
    12388168
  • Weiss RE, Korcarz C, Chassande O, Cua K, Sadow PM, Koo E, Samarut J, Lang R.Thyroid hormone and cardiac function in mice deficient in thyroid hormone receptor-alpha or -beta: an echocardiograph study.Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E428-35.
    12169435
  • Takeuchi Y, Murata Y, Sadow P, Hayashi Y, Seo H, Xu J, O'Malley BW, Weiss RE, Refetoff S.Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.Endocrinology. 2002 Apr;143(4):1346-52.
    11897691
  • Weiss RE, Gehin M, Xu J, Sadow PM, O'Malley BW, Chambon P, Refetoff S.Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.Endocrinology. 2002 Apr;143(4):1554-7.
    11897715
  • Pohlenz J, Sadow PM, Koffler T, Schönberger W, Weiss RE, Refetoff S.Congenital hypothyroidism in a child with unsuspected familial dysalbuminemic hyperthyroxinemia caused by a mutation (R218H) in the human albumin gene.J Pediatr. 2001 Dec;139(6):887-91.
    11743520
  • Reutrakul S, Sadow PM, Pannain S, Pohlenz J, Carvalho GA, Macchia PE, Weiss RE, Refetoff S.Search for abnormalities of nuclear corepressors, coactivators, and a coregulator in families with resistance to thyroid hormone without mutations in thyroid hormone receptor beta or alpha genes.J Clin Endocrinol Metab. 2000 Oct;85(10):3609-17.
    11061510
  • Pohlenz J, Manders L, Sadow PM, Kansal PC, Refetoff S, Weiss RE.A novel point mutation in cluster 3 of the thyroid hormone receptor beta gene (P247L) causing mild resistance to thyroid hormone.Thyroid. 1999 Dec;9(12):1195-203.
    10646658
  • West-Mays JA, Cook JR, Sadow PM, Mullady DK, Bargagna-Mohan P, Strissel KJ, Fini ME.Differential inhibition of collagenase and interleukin-1alpha gene expression in cultured corneal fibroblasts by TGF-beta, dexamethasone, and retinoic acid.Invest Ophthalmol Vis Sci. 1999 Apr;40(5):887-96.
    10102285
  • West-Mays JA, Sadow PM, Tobin TW, Strissel KJ, Cintron C, Fini ME.Repair phenotype in corneal fibroblasts is controlled by an interleukin-1 alpha autocrine feedback loop.Invest Ophthalmol Vis Sci. 1997 Jun;38(7):1367-79.
    9191600
  • Fini ME, Parks WC, Rinehart WB, Girard MT, Matsubara M, Cook JR, West-Mays JA, Sadow PM, Burgeson RE, Jeffrey JJ, Raizman MB, Krueger RR, Zieske JD.Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury.Am J Pathol. 1996 Oct;149(4):1287-302.
    8863676
  • West-Mays JA, Strissel KJ, Sadow PM, Fini ME.Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop.Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6768-72.
    7624317
  • Gross J, Farinelli W, Sadow P, Anderson R, Bruns R.On the mechanism of skin wound "contraction": a granulation tissue "knockout" with a normal phenotype.Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5982-6.
    7597065