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Charles J. Dimitroff, PhD


  • Burdick MM, Reynolds NM, Martin EW, Hawes JV, Carlson GE, Cuckler CM, Bates MC, Barthel SR, Dimitroff CJ.Isolation and characterization of chimeric human Fc-expressing proteins using protein a membrane adsorbers and a streamlined workflow.Journal Of Visualized Experiments : Jo Ve. 2014(83):e51023.
  • Dimitroff CJ.Leveraging fluorinated glucosamine action to boost antitumor immunity.Curr Opin Immunol. 2012 Dec 6.
  • Barthel SR, Hays D, Yazawa EM, Opperman MJ, Walley KC, Nimrichter L, Burdick MM, Gillard BM, Moser MT, Pantel K, Foster BA, Pienta KJ, Dimitroff CJ.Definition of molecular determinants of prostate cancer cell bone extravasation.Cancer Res. 2012 Nov 13.
  • Cedeno-Laurent F, Dimitroff CJ.Galectins and their ligands: negative regulators of anti-tumor immunity.Glycoconj. J. 2012 Dec;29(8-9):619-25. Review.
  • Cedeno-Laurent F, Opperman M, Barthel SR, Kuchroo VK, Dimitroff CJ.Galectin-1 triggers an immunoregulatory signature in th cells functionally defined by IL-10 expression.J Immunol. 2012 Apr 1;188(7):3127-37.
  • Cedeno-Laurent F, Dimitroff CJ.Evidence of a novel galectin-9-binding membrane glycoprotein ligand on T helper cells.Clin Immunol. 2012 Apr;143(1):6-7.
  • Cedeno-Laurent F, Watanabe R, Teague JE, Kupper TS, Clark RA, Dimitroff CJ.Galectin-1 inhibits viability, proliferation, and Th1 cytokine production of non-malignant T cells in patients with leukemic cutaneous T-cell lymphoma.Blood. 2012 Mar 1.
  • Cedeno-Laurent F, Dimitroff CJ.Galectin-1 research in T cell immunity: past, present and future.Clin Immunol. 2012 Feb;142(2):107-16.
  • Cedeno-Laurent F, Opperman MJ, Barthel SR, Hays D, Schatton T, Zhan Q, He X, Matta KL, Supko JG, Frank MH, Murphy GF, Dimitroff CJ.Metabolic Inhibition of Galectin-1-Binding Carbohydrates Accentuates Antitumor Immunity.J Invest Dermatol. 2011 Dec 8.
  • Barthel SR, Antonopoulos A, Cedeno-Laurent F, Schaffer L, Hernandez G, Patil SA, North SJ, Dell A, Matta KL, Neelamegham S, Haslam SM, Dimitroff CJ.Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.J Biol Chem. 2011 Jun 17;286(24):21717-31.
  • Cedeno-Laurent F, Barthel SR, Opperman MJ, Lee DM, Clark RA, Dimitroff CJ.Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation.J Immunol. 2010 Oct 15;185(8):4659-72.
  • Barthel SR, Wiese GK, Cho J, Opperman MJ, Hays DL, Siddiqui J, Pienta KJ, Furie B, Dimitroff CJ.Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking.Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19491-6.
  • Wiese G, Barthel SR, Dimitroff CJ.Analysis of physiologic E-selectin-mediated leukocyte rolling on microvascular endothelium.Journal Of Visualized Experiments : Jo Ve. 2009(24).
  • Barthel SR, Gavino JD, Wiese GK, Jaynes JM, Siddiqui J, Dimitroff CJ.Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin.Glycobiology. 2008 Oct;18(10):806-17.
  • Gainers ME, Descheny L, Barthel SR, Liu L, Wurbel MA, Dimitroff CJ.Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis.J Immunol. 2007 Dec 15;179(12):8509-18.
  • Barthel SR, Gavino JD, Descheny L, Dimitroff CJ.Targeting selectins and selectin ligands in inflammation and cancer.Expert Opin Ther Targets. 2007 Nov;11(11):1473-91. Review.
  • Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS.Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression.J Allergy Clin Immunol. 2008 Jan;121(1):148-157.e3.
  • Alcaide P, King SL, Dimitroff CJ, Lim YC, Fuhlbrigge RC, Luscinskas FW.The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo.J Invest Dermatol. 2007 Aug;127(8):1964-72.
  • Descheny L, Gainers ME, Walcheck B, Dimitroff CJ.Ameliorating skin-homing receptors on malignant T cells with a fluorosugar analog of N-acetylglucosamine: P-selectin ligand is a more sensitive target than E-selectin ligand.J Invest Dermatol. 2006 Sep;126(9):2065-73.
  • Dimitroff CJ, Descheny L, Trujillo N, Kim R, Nguyen V, Huang W, Pienta KJ, Kutok JL, Rubin MA.Identification of leukocyte E-selectin ligands, P-selectin glycoprotein ligand-1 and E-selectin ligand-1, on human metastatic prostate tumor cells.Cancer Res. 2005 Jul 1;65(13):5750-60.
  • Dimitroff CJ, Lechpammer M, Long-Woodward D, Kutok JL.Rolling of Human Bone-Metastatic Prostate Tumor Cells on Human Bone Marrow Endothelium under Shear Flow Is Mediated by E-Selectin.Cancer Res. 2004 Aug 1;64(15):5261-9.
  • Dimitroff CJ, Kupper TS, Sackstein R.Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen.J Clin Invest. 2003 Oct;112(7):1008-18.
  • Dimitroff CJ, Bernacki RJ, Sackstein R.Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen expression: implications in modulating lymphocyte migration to skin.Blood. 2003 Jan 15;101(2):602-10.
  • Fuhlbrigge RC, King SL, Dimitroff CJ, Kupper TS, Sackstein R.Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots.J Immunol. 2002 Jun 1;168(11):5645-51.
  • Dimitroff CJ, Lee JY, Fuhlbrigge RC, Sackstein R.A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells.Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13841-6.
  • Sackstein R, Dimitroff CJ.A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity.Blood. 2000 Oct 15;96(8):2765-74.