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Javid J. Moslehi, MD

Publications

  • Zheng X, Zhai B, Koivunen P, Shin SJ, Lu G, Liu J, Geisen C, Chakraborty AA, Moslehi JJ, Smalley DM, Wei X, Chen X, Chen Z, Beres JM, Zhang J, Tsao JL, Brenner MC, Zhang Y, Fan C, DePinho RA, Paik J, Gygi SP, Kaelin WG, Zhang Q.Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.Genes Dev. 2014 Jul 1;28(13):1429-44.
    24990963
  • Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D.Survivorship: fatigue, version 1.2014.J Natl Compr Canc Netw. 2014 Jun;12(6):876-87.
    24925198
  • Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D.Survivorship: sleep disorders, version 1.2014.J Natl Compr Canc Netw. 2014 May;12(5):630-42.
    24812132
  • Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D.Survivorship: pain version 1.2014.J Natl Compr Canc Netw. 2014 Apr 1;12(4):488-500.
    24717568
  • Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA.Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.Cell. 2013 Dec 19;155(7):1624-38.
    24360282
  • Ky B, Vejpongsa P, Yeh ET, Force T, Moslehi JJ.Emerging paradigms in cardiomyopathies associated with cancer therapies.Circ Res. 2013 Aug 30;113(6):754-64. Review.
    23989717
  • Groarke JD, Nguyen PL, Nohria A, Ferrari R, Cheng S, Moslehi J.Cardiovascular complications of radiation therapy for thoracic malignancies: the role for non-invasive imaging for detection of cardiovascular disease.Eur Heart J. 2013 May 10.
    23666251
  • Bair SM, Choueiri TK, Moslehi J.Cardiovascular complications associated with novel angiogenesis inhibitors: Emerging evidence and evolving perspectives.Trends Cardiovasc. Med. 2013 May;23(4):104-13.
    23290365
  • Moslehi J.The cardiovascular perils of cancer survivorship.N Engl J Med. 2013 Mar 14;368(11):1055-6.
    23484833
  • Groarke J, Tong D, Khambhati J, Cheng S, Moslehi J.Breast cancer therapies and cardiomyopathy.Med Clin North Am. 2012 Sep;96(5):1001-19.
    22980061
  • de Jesus-Gonzalez N, Robinson E, Moslehi J, Humphreys BD.Management of antiangiogenic therapy-induced hypertension.Hypertension. 2012 Sep;60(3):607-15.
    22851729
  • Richards CJ, Je Y, Schutz FA, Heng DY, Dallabrida SM, Moslehi JJ, Choueiri TK.Incidence and risk of congestive heart failure in patients with renal and nonrenal cell carcinoma treated with sunitinib.J Clin Oncol. 2011 Sep 1;29(25):3450-6.
    21810682
  • Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA.Telomere dysfunction induces metabolic and mitochondrial compromise.Nature. 2011 Feb 17;470(7334):359-65.
    21307849
  • Moslehi J, Minamishima YA, Shi J, Neuberg D, Charytan DM, Padera RF, Signoretti S, Liao R, Kaelin WG.Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.Circulation. 2010 Sep 7;122(10):1004-16.
    20733101
  • Minamishima YA, Moslehi J, Padera RF, Bronson RT, Liao R, Kaelin WG.A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.Mol Cell Biol. 2009 Nov;29(21):5729-41.
    19720742
  • Joynt KE, Moslehi JJ, Baughman KL.Paragangliomas: etiology, presentation, and management.Cardiol Rev.;17(4):159-64. Review.
    19525677
  • Sung AD, Cheng S, Moslehi J, Scully EP, Prior JM, Loscalzo J.Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature.Am J Cardiol. 2008 Sep 1;102(5):643-5.
    18721529
  • Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG.Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.Blood. 2008 Mar 15;111(6):3236-44.
    18096761
  • Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA.cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.Circ Res. 2005 Jan 7;96(1):100-9.
    15576651