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Gaudenz Danuser, PhD


  • Ng MR, Besser A, Danuser G, Brugge JS.Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility.J Cell Biol. 2012 Oct 29;199(3):545-63.
  • Nishimura Y, Applegate K, Davidson MW, Danuser G, Waterman CM.Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells.PLoS ONE. 2012;7(7):e41413.
  • Loerke D, le Duc Q, Blonk I, Kerstens A, Spanjaard E, Machacek M, Danuser G, de Rooij J.Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation.Sci Signal. 2012 Jul 3;5(231):rs5.
  • Loerke D, Mettlen M, Schmid SL, Danuser G.Measuring the hierarchy of molecular events during clathrin-mediated endocytosis.Traffic. 2011 Mar 29.
  • Mendoza MC, Er EE, Zhang W, Ballif BA, Elliott HL, Danuser G, Blenis J.ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex.Mol Cell. 2011 Mar 18;41(6):661-71.
  • Myers KA, Applegate KT, Danuser G, Fischer RS, Waterman CM.Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis.J Cell Biol. 2011 Jan 24;192(2):321-34.
  • Liu AP, Aguet F, Danuser G, Schmid SL.Local clustering of transferrin receptors promotes clathrin-coated pit initiation.J Cell Biol. 2010 Dec 27;191(7):1381-93.
  • Thoma CR, Matov A, Gutbrodt KL, Hoerner CR, Smole Z, Krek W, Danuser G.Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability.J Cell Biol. 2010 Sep 20;190(6):991-1003.
  • Matov A, Applegate K, Kumar P, Thoma C, Krek W, Danuser G, Wittmann T.Analysis of microtubule dynamic instability using a plus-end growth marker.Nat Methods. 2010 Sep;7(9):761-8.
  • Antonescu CN, Danuser G, Schmid SL.Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis.Mol Biol Cell. 2010 Aug 15;21(16):2944-52.
  • Lim JI, Sabouri-Ghomi M, Machacek M, Waterman CM, Danuser G.Protrusion and actin assembly are coupled to the organization of lamellar contractile structures.Exp Cell Res. 2010 Aug 1;316(13):2027-41.
  • Wilson CA, Tsuchida MA, Allen GM, Barnhart EL, Applegate KT, Yam PT, Ji L, Keren K, Danuser G, Theriot JA.Myosin II contributes to cell-scale actin network treadmilling through network disassembly.Nature. 2010 May 20;465(7296):373-7.
  • Enculescu M, Sabouri-Ghomi M, Danuser G, Falcke M.Modeling of protrusion phenotypes driven by the actin-membrane interaction.Biophys J. 2010 Apr 21;98(8):1571-81.
  • Mettlen M, Loerke D, Yarar D, Danuser G, Schmid SL.Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis.J Cell Biol. 2010 Mar 22;188(6):919-33.
  • Jaqaman K, King EM, Amaro AC, Winter JR, Dorn JF, Elliott HL, McHedlishvili N, McClelland SE, Porter IM, Posch M, Toso A, Danuser G, McAinsh AD, Meraldi P, Swedlow JR.Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases.J Cell Biol. 2010 Mar 8;188(5):665-79.
  • Gatlin JC, Matov A, Danuser G, Mitchison TJ, Salmon ED.Directly probing the mechanical properties of the spindle and its matrix.J Cell Biol. 2010 Feb 22;188(4):481-9.
  • Machacek M, Hodgson L, Welch C, Elliott H, Pertz O, Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser G.Coordination of Rho GTPase activities during cell protrusion.Nature. 2009 Sep 3;461(7260):99-103.
  • Loerke D, Mettlen M, Yarar D, Jaqaman K, Jaqaman H, Danuser G, Schmid SL.Cargo and dynamin regulate clathrin-coated pit maturation.PLoS Biol. 2009 Mar 17;7(3):e57.
  • Ji L, Lim J, Danuser G.Fluctuations of intracellular forces during cell protrusion.Nat Cell Biol. 2008 Dec;10(12):1393-400.