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Daniela M. Dinulescu, Ph.D.

Publications

  • Morgan SL, Wyant GA, Dinulescu DM."Take it up a NOTCH": novel strategies for cancer therapy.Cell Cycle. 2013 Jan 15;12(2):191-2.
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  • McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, Chen YS, Chin KT, Partridge JC, Poole BB, Cheng KH, Daggett J, Cullen K, Kantoff E, Hasselbatt K, Berkowitz J, Muto MG, Berkowitz RS, Aster JC, Matulonis UA, Dinulescu DM.Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):E2939-48.
    23019585
  • Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S.Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity.Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11294-9.
    22733767
  • Paraskar AS, Soni S, Chin KT, Chaudhuri P, Muto KW, Berkowitz J, Handlogten MW, Alves NJ, Bilgicer B, Dinulescu DM, Mashelkar RA, Sengupta S.Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy.Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12435-40.
    20616005
  • Pitteri SJ, JeBailey L, Fa├ža VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM.Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.PLoS ONE. 2009;4(11):e7916.
    19936259
  • Romero IL, Gordon IO, Jagadeeswaran S, Mui KL, Lee WS, Dinulescu DM, Krausz TN, Kim HH, Gilliam ML, Lengyel E.Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.Cancer Prev Res (Phila Pa). 2009 Sep;2(9):792-9.
    19737983
  • Abbott KL,Nairn AV,Hall EM,Horton MB,McDonald JF,Moremen KW,Dinulescu DM,Pierce M.Focused glycomic analysis of the N-linked glycan biosynthetic pathway in ovarian cancer.Proteomics. 2008 Aug;8(16):3210-20.
    18690643
  • Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, Dinulescu DM, Lengyel E, Peter ME.Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.Cell Cycle. 2007 Aug;6(21):2585-90.
    17957144
  • Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T.A spatially and temporally restricted mouse model of soft tissue sarcoma.Nat Med. 2007 Aug;13(8):992-7.
    17676052
  • Pieretti-Vanmarcke R, Donahoe PK, Pearsall LA, Dinulescu DM, Connolly DC, Halpern EF, Seiden MV, MacLaughlin DT.Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17426-31.
    17088539
  • Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R, Dombkowski D, Preffer F, Maclaughlin DT, Donahoe PK.Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness.Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11154-9.
    16849428
  • Daikoku T, Tranguch S, Trofimova IN, Dinulescu DM, Jacks T, Nikitin AY, Connolly DC, Dey SK.Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.Cancer Res. 2006 Mar 1;66(5):2527-31.
    16510568
  • Dinulescu DM, Ince TA, Quade BJ, Shafer SA, Crowley D, Jacks T.Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer.Nat Med. 2005 Jan;11(1):63-70.
    15619626
  • Dinulescu DM, Wood LJ, Shen L, Loriaux M, Corless CL, Gross AW, Ren R, Deininger MW, Druker BJ.c-CBL is not required for leukemia induction by Bcr-Abl in mice.Oncogene. 2003 Dec 4;22(55):8852-60.
    14654781