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David Barbie, MD

Publications

  • Golay HG, Barbie DA.Targeting cytokine networks in KRAS-driven tumorigenesis.Expert Rev Anticancer Ther. 2014 Jun 13:1-3.
    24928447
  • Placke T, Faber K, Nonami A, Putwain SL, Salih HR, Heidel FH, Krämer A, Root DE, Barbie DA, Krivtsov AV, Armstrong SA, Hahn WC, Huntly BJ, Sykes SM, Milsom MD, Scholl C, Fröhling S.Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.Blood. 2014 Apr 24.
    24764564
  • Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA.Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.Cancer Discovery. 2014 Apr;4(4):452-65.
    24444711
  • Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC.Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.Cancer Discovery. 2013 Sep;3(9):1044-57.
    23764425
  • Tu D, Zhu Z, Zhou AY, Yun CH, Lee KE, Toms AV, Li Y, Dunn GP, Chan E, Thai T, Yang S, Ficarro SB, Marto JA, Jeon H, Hahn WC, Barbie DA, Eck MJ.Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1.Cell Rep. 2013 Mar 28;3(3):747-58.
    23453972
  • Moody SE, Boehm JS, Barbie DA, Hahn WC.Functional genomics and cancer drug target discovery.Curr Opin Mol Ther. 2010 Jun;12(3):284-93. Review.
    20521217
  • Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC.Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.Nature. 2009 Nov 5;462(7269):108-12.
    19847166