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David Barbie, MD

Publications

  • Tu D, Zhu Z, Zhou AY, Yun CH, Lee KE, Toms AV, Li Y, Dunn GP, Chan E, Thai T, Yang S, Ficarro SB, Marto JA, Jeon H, Hahn WC, Barbie DA, Eck MJ.Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1.Cell Rep. 2013 Mar 28;3(3):747-58.
    23453972
  • Moody SE, Boehm JS, Barbie DA, Hahn WC.Functional genomics and cancer drug target discovery.Curr Opin Mol Ther. 2010 Jun;12(3):284-93. Review.
    20521217
  • Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC.Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.Nature. 2009 Nov 5;462(7269):108-12.
    19847166