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Joanna Yeh, PhD

Publications

  • Zhang Y, Wang J, Wheat J, Chen X, Jin S, Sadrzadeh H, Fathi AT, Peterson RT, Kung AL, Sweetser DA, Yeh JR.AML1-ETO mediates hematopoietic self-renewal and leukemogenesis through a COX/β-catenin signaling pathway.Blood. 2013 May 3.
    23645839
  • Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JR, Joung JK.Efficient genome editing in zebrafish using a CRISPR-Cas system.Nat Biotechnol. 2013 Jan 29.
    23360964
  • Cade L, Reyon D, Hwang WY, Tsai SQ, Patel S, Khayter C, Joung JK, Sander JD, Peterson RT, Yeh JR.Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.Nucleic Acids Res. 2012 Sep;40(16):8001-10.
    22684503
  • Cunningham L, Finckbeiner S, Hyde RK, Southall N, Marugan J, Yedavalli VR, Dehdashti SJ, Reinhold WC, Alemu L, Zhao L, Yeh JR, Sood R, Pommier Y, Austin CP, Jeang KT, Zheng W, Liu P.Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction.Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14592-7.
    22912405
  • Zhang Y, Yeh JR.In vivo chemical screening for modulators of hematopoiesis and hematological diseases.Adv Hematol. 2012;2012:851674.
    22778745
  • Helenius IT, Yeh JR.Small zebrafish in a big chemical pond.J Cell Biochem. 2012 Jul;113(7):2208-16. Review.
    22396148
  • Yeh JR.A Wnt inhibitor with a twist.Chem Biol. 2011 Dec 23;18(12):1518-20.
    22195553
  • Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR.Targeted gene disruption in somatic zebrafish cells using engineered TALENs.Nat Biotechnol. 2011 Aug;29(8):697-8.
    21822241
  • Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK.Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).Nat Methods. 2011 Jan;8(1):67-9.
    21151135
  • Yeh JR, Munson KM.Zebrafish small molecule screen in reprogramming/cell fate modulation.Methods Mol Biol. 2010;636:317-27.
    20336532
  • Foley JE, Maeder ML, Pearlberg J, Joung JK, Peterson RT, Yeh JR.Targeted mutagenesis in zebrafish using customized zinc-finger nucleases.Nat Protoc. 2009;4(12):1855-67.
    20010934
  • Yeh JR,Munson KM,Elagib KE,Goldfarb AN,Sweetser DA,Peterson RT.Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.Nat Chem Biol. 2009 Apr;5(4):236-43.
    19172146
  • Dayyani F, Wang J, Yeh JR, Ahn EY, Tobey E, Zhang DE, Bernstein ID, Peterson RT, Sweetser DA.Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperate with AML1-ETO to affect myeloid cell proliferation and survival.Blood. 2008 Apr 15;111(8):4338-47.
    18258796
  • Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT.AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression.Development. 2008 Jan;135(2):401-10.
    18156164