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Jane Yu, PhD

Publications

  • Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J.The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.Cell. 2013 May 9;153(4):840-54.
    23663782
  • Li C, Zhou X, Sun Y, Zhang E, Mancini JD, Parkhitko A, Morrison TA, Silverman EK, Henske EP, Yu JJ.Faslodex Inhibits Estradiol-induced ECM Dynamics and Lung Metastasis in a Model of LAM.Am J Respir Cell Mol Biol. 2013 Mar 22.
    23526212
  • Trindade AJ, Medvetz DA, Neuman NA, Myachina F, Yu J, Priolo C, Henske EP.MicroRNA-21 is induced by rapamycin in a model of tuberous sclerosis (TSC) and lymphangioleiomyomatosis (LAM).PLoS ONE. 2013;8(3):e60014.
    23555865
  • Liu F, Lunsford EP, Tong J, Ashitate Y, Gibbs SL, Yu J, Choi HS, Henske EP, Frangioni JV.Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex.PLoS ONE. 2012;7(6):e38589.
    22719903
  • Andrey Parkhitko, Faina Myachina, Tasha Morrison, Neil Auricchio, Magdalena Karbowniczek, Kevin Marks, Edward Driggers, Julia Wu, Toren Finkel, David Kwiatkowski, *Jane Yu and Elizabeth Petri Henske. (*Co-coresponding author).Dysregulation of Autophagy in Tuberous Sclerosis Promotes Renal Tumorigenesis.Cancer Cell..
  • Yu, Jane .Tuberous Sclerosis Complex and the Mammalian Target of Rapamycin Pathways. .ELS. 9/2010.
  • Jane Yu and Elizabeth Petri Henske. .Dysregulation of TOR Signaling in Tuberous Sclerosis and Lymphangioleiomyomotosis. .The Enzymes_Volume 27 - Chapter 16: pp303-327. Burlington: Academic Press, 2010, pp.303-327..
  • Jane Yu and Elizabeth Petri Henske.mTOR activation, Lymphangiogenesis, and estrogen-mediated cell survival: The "perfect storm" of pro-metastatic factors in LAM pathogenesis. .LRB..
  • Jane Yu, Andrey A. Parkhitko, and Elizabeth Petri Henske.Mammalian Target of Rapamycin Signaling and Autophagy: Roles in Lymphangioleiomyomatosis. .PATS..
  • Magdalena Karbowniczek, Diana Zitserman, Damir Khabibullin, Tiffiney Hartman, Jane Yu, Tasha Morrison, Emmanuelle Nicolas, Rachel Squillace, Fabrice Roegiers and Elizabeth Petri Henske. .The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development. .JCI..
  • Yu JJ,Robb VA,Morrison TA,Ariazi EA,Karbowniczek M,Astrinidis A,Wang C,Hernandez-Cuebas L,Seeholzer LF,Nicolas E,Hensley H,Jordan VC,Walker CL,Henske EP.Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2635-40.
    19202070
  • Li F, Vallabhaneni R, Yu J, Rocheford T, Wurtzel ET. .The maize phytoene synthase gene family: overlapping roles for carotenogenesis in endosperm, photomorphogenesis, and thermal stress tolerance. .
  • Yu J, Henske EP.Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain. .
  • Yu J, Astrinidis A, Howard S, Henske EP.Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways.
  • Karbowniczek M, Yu J, Henske EP.Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures. .
  • Yu J, Astrinidis A, Henske EP.Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis.