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Natasha Y. Frank, M.D.


  • Wilson BJ, Saab KR, Ma J, Schatton T, Pütz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH.ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit.Cancer Res. 2014 Aug 1;74(15):4196-207.
  • Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY.ABCB5 is a limbal stem cell gene required for corneal development and repair.Nature. 2014 Jul 17;511(7509):353-7.
  • Volpicelli ER, Lezcano C, Zhan Q, Girouard SD, Kindelberger DW, Frank MH, Frank NY, Crum CP, Murphy GF.The multidrug-resistance transporter ABCB5 is expressed in human placenta.Int J Gynecol Pathol. 2014 Jan;33(1):45-51.
  • Murphy GF, Wilson BJ, Girouard SD, Frank NY, Frank MH.Stem cells and targeted approaches to melanoma cure.Mol Aspects Med. 2013 Oct 19.
  • Lin JY, Zhang M, Schatton T, Wilson BJ, Alloo A, Ma J, Qureshi AA, Frank NY, Han J, Frank MH.Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk.Biochem Biophys Res Commun. 2013 Jun 11.
  • Wilson BJ, Schatton T, Zhan Q, Gasser M, Ma J, Saab KR, Schanche R, Waaga-Gasser AM, Gold JS, Huang Q, Murphy GF, Frank MH, Frank NY.ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients.Cancer Res. 2011 Jun 7.
  • Wilson BJ, Schatton T, Frank MH, Frank NY.Colorectal Cancer Stem Cells: Biology and Therapeutic Implications.Current Colorectal Cancer Reports. 2011 Jun;7(2):128-135.
  • Frank NY, Schatton T, Kim S, Zhan Q, Wilson BJ, Ma J, Saab KR, Osherov V, Widlund HR, Gasser M, Waaga-Gasser AM, Kupper TS, Murphy GF, Frank MH.VEGFR-1 expressed by malignant melanoma initiating cells is required for tumor growth.Cancer Res. 2011 Jan 11.
  • Ma J, Lin JY, Alloo A, Wilson BJ, Schatton T, Zhan Q, Murphy GF, Waaga-Gasser AM, Gasser M, Hodi FS, Frank NY, Frank MH.Isolation of tumorigenic circulating melanoma cells.Biochem Biophys Res Commun. 2010 Nov 26;402(4):711-7.
  • Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH.A novel in vivo regulatory role of P-glycoprotein in alloimmunity.Biochem Biophys Res Commun. 2010 Apr 9;394(3):646-52.
  • Schatton T, Schütte U, Frank NY, Zhan Q, Hoerning A, Robles SC, Zhou J, Hodi FS, Spagnoli GC, Murphy GF, Frank MH.Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells.Cancer Res. 2010 Jan 15;70(2):697-708.
  • Frank NY, Schatton T, Frank MH.The therapeutic promise of the cancer stem cell concept.J Clin Invest. 2010 Jan;120(1):41-50. Review.
  • Schatton T, Frank NY, Frank MH.Identification and targeting of cancer stem cells.Bioessays. 2009 Oct;31(10):1038-49. Review.
  • Frank NY,Frank MH.ABCB5 gene amplification in human leukemia cells.Leuk Res. 2009 Oct;33(10):1303-5.
  • Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH.Identification of cells initiating human melanomas.Nature. 2008 Jan 17;451(7176):345-9.
  • Frank NY, Kho AT, Schatton T, Murphy GF, Molloy MJ, Zhan Q, Ramoni MF, Frank MH, Kohane IS, Gussoni E.Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.J Cell Biol. 2006 Oct 9;175(1):99-110.
  • Muskiewicz KR, Frank NY, Flint AF, Gussoni E.Myogenic potential of muscle side and main population cells after intravenous injection into sub-lethally irradiated mdx mice.J. Histochem. Cytochem. 2005 Jul;53(7):861-73.
  • Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, Frank MH.ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma.Cancer Res. 2005 May 15;65(10):4320-33.
  • Frank NY, Pendse SS, Lapchak PH, Margaryan A, Shlain D, Doeing C, Sayegh MH, Frank MH.Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter.J Biol Chem. 2003 Nov 21;278(47):47156-65.