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Leonid Mirny, PhD

Publications

  • Weisberg SP, Smith-Raska MR, Esquilin JM, Zhang J, Arenzana TL, Lau CM, Churchill M, Pan H, Klinakis A, Dixon JE, Mirny LA, Mukherjee S, Reizis B.ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.Cell Rep. 2014 Feb 13;6(3):528-40.
    24485662
  • Naumova N, Imakaev M, Fudenberg G, Zhan Y, Lajoie BR, Mirny LA, Dekker J.Organization of the mitotic chromosome.Science. 2013 Nov 22;342(6161):948-53.
    24200812
  • Le TB, Imakaev MV, Mirny LA, Laub MT.High-resolution mapping of the spatial organization of a bacterial chromosome.Science. 2013 Nov 8;342(6159):731-4.
    24158908
  • Dekker J, Mirny L.Biological techniques: Chromosomes captured one by one.Nature. 2013 Oct 3;502(7469):45-6.
    24067607
  • Dekker J, Marti-Renom MA, Mirny LA.Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.Nat Rev Genet. 2013 May 9.
    23657480
  • McFarland CD, Korolev KS, Kryukov GV, Sunyaev SR, Mirny LA.Impact of deleterious passenger mutations on cancer progression.Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2910-5.
    23388632
  • Leith JS, Tafvizi A, Huang F, Uspal WE, Doyle PS, Fersht AR, Mirny LA, van Oijen AM.Sequence-dependent sliding kinetics of p53.Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16552-7.
    23012405
  • Engreitz JM, Agarwala V, Mirny LA.Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.PLoS ONE. 2012;7(9):e44196.
    23028501
  • Imakaev M, Fudenberg G, McCord RP, Naumova N, Goloborodko A, Lajoie BR, Dekker J, Mirny LA.Iterative correction of Hi-C data reveals hallmarks of chromosome organization.Nat Methods. 2012 Oct;9(10):999-1003.
    22941365
  • Mirny LA.The fractal globule as a model of chromatin architecture in the cell.Chromosome Res. 2011 Jan;19(1):37-51.
    21274616
  • Tafvizi A, Huang F, Fersht AR, Mirny LA, van Oijen AM.A single-molecule characterization of p53 search on DNA.Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):563-8.
    21178072
  • Wunderlich Z, Mirny LA.Different gene regulation strategies revealed by analysis of binding motifs.Trends Genet. 2009 Oct;25(10):434-40.
    19815308
  • Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J.Comprehensive mapping of long-range interactions reveals folding principles of the human genome.Science. 2009 Oct 9;326(5950):289-93.
    19815776
  • Wunderlich Z, Mirny LA.Using genome-wide measurements for computational prediction of SH2-peptide interactions.Nucleic Acids Res. 2009 Aug;37(14):4629-41.
    19502496
  • Galan-Caridad JM, Harel S, Arenzana TL, Hou ZE, Doetsch FK, Mirny LA, Reizis B.Zfx controls the self-renewal of embryonic and hematopoietic stem cells.Cell. 2007 Apr 20;129(2):345-57.
    17448993