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Trista E. North, PhD


  • Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Vander Heiden MG, Goessling W, North TE.Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo.Blood. 2013 Mar 28;121(13):2483-93.
  • Garnaas MK, Cutting CC, Meyers A, Kelsey PB, Harris JM, North TE, Goessling W.Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.Dev Biol. 2012 Dec 15;372(2):178-89.
  • Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH.Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis.Dev Biol. 2012 Aug 29.
  • Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, Goessling W, Sunyaev SR.Mutation mapping and identification by whole-genome sequencing.Genome Res. 2012 Aug;22(8):1541-8.
  • Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, Donahue RE, North TE.Prostaglandin e2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.Cell Stem Cell. 2011 Apr 8;8(4):445-58.
  • North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W.PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17315-20.
  • Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA.The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.Science. 2010 Mar 26;327(5973):1650-3.
  • North TE, Goessling W.Previews. NOTCHing an arrow at cord blood: translating stem cell knowledge into clinical practice.Cell Stem Cell. 2010 Mar 5;6(3):186-7.
  • North TE,Goessling W,Peeters M,Li P,Ceol C,Lord AM,Weber GJ,Harris J,Cutting CC,Huang P,Dzierzak E,Zon LI.Hematopoietic stem cell development is dependent on blood flow.Cell. 2009 May 15;137(4):736-48.
  • Goessling W,North TE,Loewer S,Lord AM,Lee S,Stoick-Cooper CL,Weidinger G,Puder M,Daley GQ,Moon RT,Zon LI.Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration.Cell. 2009 Mar 20;136(6):1136-47.
  • Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI.APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development.Dev Biol. 2008 Aug 1;320(1):161-74.
  • North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI.Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.Nature. 2007 Jun 21;447(7147):1007-11.