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Christene A. Huang, PhD


  • Madariaga ML, Michel SG, La Muraglia GM, Sihag S, Leonard DA, Farkash EA, Colvin RB, Cetrulo CL, Huang CA, Sachs DH, Madsen JC, Allan JS.
    Recipient-Matching of Passenger Leukocytes Prolongs Survival of Donor Lung Allografts in Miniature Swine.
    Transplantation. 2015 Mar 9.
  • Peraino JS, Zhang H, Rajasekera PV, Wei M, Madsen JC, Sachs DH, Huang CA, Wang Z.
    Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells.
    J Immunol Methods. 2014 Mar;405:57-66.
  • Liang F, Wamala I, Scalea J, Tena A, Cormack T, Pratts S, Duran-Struuck R, Elias N, Hertl M, Huang CA, Sachs DH.
    Increased levels of anti-non-Gal IgG following pig-to-baboon bone marrow transplantation correlate with failure of engraftment.
  • Wamala I, Matar AJ, Farkash E, Wang Z, Huang CA, Sachs DH.
    Recombinant anti-monkey CD3 immunotoxin depletes peripheral lymph node T lymphocytes more effectively than rabbit anti-thymocyte globulin in naïve baboons.
    Transpl Immunol. 2013 Dec;29(1-4):60-3.
  • Peraino JS, Schenk M, Li G, Zhang H, Farkash EA, Sachs DH, Huang CA, Duran-Struuck R, Wang Z.
    Development of a diphtheria toxin-based recombinant porcine IL-2 fusion toxin for depleting porcine CD25+ cells.
    J Immunol Methods. 2013 Dec 15;398-399:33-43.
  • Matar AJ, Crepeau RL, Pathiraja V, Robson S, Fishman JA, Spitzer TR, Sachs DH, Huang CA, Duran-Struuck R.
    Effects of mobilization regimens in donors on outcomes of hematopoietic cell transplantation in miniature Swine.
    Comp Med. 2012;62(6):487-94.
  • Pathiraja V, Matar AJ, Gusha A, Huang CA, Duran-Struuck R.
    Leukapheresis protocol for nonhuman primates weighing less than 10 kg.
    J Am Assoc Lab Anim Sci. 2013;52(1):70-7.
  • Peraino JS, Schenk M, Zhang H, Li G, Hermanrud CE, Neville DM, Sachs DH, Huang CA, Duran-Struuck R, Wang Z.
    A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin.
    J Immunol Methods. 2013 Mar 5.
  • Duran-Struuck R, Matar A, Crepeau R, Gusha A, Schenk M, Hanekamp I, Pathiraja V, Spitzer TR, Sachs DH, Huang CA.
    Lack of antidonor alloantibody does not indicate lack of immune sensitization: studies of graft loss in a haploidentical hematopoietic cell transplantation Swine model.
    Biol Blood Marrow Transplant. 2012 Nov;18(11):1629-37.
  • Crepeau R, Matar A, Spitzer TR, Robson S, Pathiraja V, Sachs DH, Huang CA, Duran-Struuck R.
    Edema and tetraparesis in a miniature pig after allogeneic hematopoietic cell transplantation.
    Comp Med. 2012 Aug;62(4):298-302.
  • Matar AJ, Pathiraja V, Wang Z, Duran-Struuck R, Gusha A, Crepeau R, Tasaki M, Sachs DH, Huang CA.
    Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment.
    Transpl Immunol. 2012 Aug;27(1):52-4.
  • Peraino JS, Hermanrud CE, Springett L, Zhang H, Li G, Srinivasan S, Gusha A, Sachs DH, Huang CA, Wang Z.
    Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15.
    Cell Immunol.;276(1-2):162-7.
  • Lutton BV, Cho PS, Hirsh EL, Ferguson KK, Teague AG, Hanekamp JS, Chi N, Goldman SN, Messina DJ, Houser S, Yeap BY, Popma SH, Sachs DH, Huang CA.
    Approaches to avoid immune responses induced by repeated subcutaneous injections of allogeneic umbilical cord tissue-derived cells.
    Transplantation. 2010 Sep 15;90(5):494-501.
  • Hermanrud CE, Lucas CL, Sykes M, Huang CA, Wang Z.
    Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris.
    Protein Expr Purif. 2011 Mar;76(1):115-20.
  • Duran-Struuck R, Cho PS, Teague AG, Fishman B, Fishman AS, Hanekamp JS, Moran SG, Wikiel KJ, Ferguson KK, Lo DP, Duggan M, Arn JS, Billiter B, Horner B, Houser S, Yeap BY, Westmoreland SV, Spitzer TR, McMorrow IM, Sachs DH, Bronson RT, Huang CA.
    Myelogenous leukemia in adult inbred MHC-defined miniature swine: A model for human myeloid leukemias.
    Veterinary Immunology And Immunopathology. 2010 Jun 15;135(3-4):243-56.
  • Cho PS, Messina DJ, Hirsh EL, Chi N, Goldman SN, Lo DP, Harris IR, Popma SH, Sachs DH, Huang CA.
    Immunogenicity of umbilical cord tissue derived cells.
    Blood. 2008 Jan 1;111(1):430-8.
  • Cho PS, Lo DP, Wikiel KJ, Rowland HC, Coburn RC, McMorrow IM, Goodrich JG, Arn JS, Billiter RA, Houser SL, Shimizu A, Yang YG, Sachs DH, Huang CA.
    Establishment of transplantable porcine tumor cell lines derived from MHC-inbred miniature swine.
    Blood. 2007 Dec 1;110(12):3996-4004.
  • Horner BM, Cina RA, Wikiel KJ, Lima B, Ghazi A, Lo DP, Yamada K, Sachs DH, Huang CA.
    Predictors of organ allograft tolerance following hematopoietic cell transplantation.
    Am J Transplant. 2006 Dec;6(12):2894-902.
  • Cina RA, Wikiel KJ, Lee PW, Cameron AM, Hettiarachy S, Rowland H, Goodrich J, Colby C, Spitzer TR, Neville DM, Huang CA.
    Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation.
    Transplantation. 2006 Jun 27;81(12):1677-85.
  • Cho PS, Mueller NJ, Cameron AM, Cina RA, Coburn RC, Hettiaratchy S, Melendy E, Neville DM, Patience C, Fishman JA, Sachs DH, Huang CA.
    Risk factors for the development of post-transplant lymphoproliferative disorder in a large animal model.
    Am J Transplant. 2004 Aug;4(8):1274-82.
  • Lima B, Gleit ZL, Cameron AM, Germana S, Murphy MC, Consorti R, Chang Q, Down JD, LeGuern C, Sachs DH, Huang CA.
    Engraftment of quiescent progenitors and conversion to full chimerism after nonmyelosuppressive conditioning and hematopoietic cell transplantation in miniature swine.
    Biol Blood Marrow Transplant. 2003 Sep;9(9):571-82.
  • Goltz M, Ericsson T, Patience C, Huang CA, Noack S, Sachs DH, Ehlers B.
    Sequence analysis of the genome of porcine lymphotropic herpesvirus 1 and gene expression during posttransplant lymphoproliferative disease of pigs.
    Virology. 2002 Mar 15;294(2):383-93.
  • Huang CA, Fuchimoto Y, Gleit ZL, Ericsson T, Griesemer A, Scheier-Dolberg R, Melendy E, Kitamura H, Fishman JA, Ferry JA, Harris NL, Patience C, Sachs DH.
    Posttransplantation lymphoproliferative disease in miniature swine after allogeneic hematopoietic cell transplantation: similarity to human PTLD and association with a porcine gammaherpesvirus.
    Blood. 2001 Mar 1;97(5):1467-73.
  • Fuchimoto Y, Huang CA, Yamada K, Shimizu A, Kitamura H, Colvin RB, Ferrara V, Murphy MC, Sykes M, White-Scharf M, Neville DM, Sachs DH.
    Mixed chimerism and tolerance without whole body irradiation in a large animal model.
    J Clin Invest. 2000 Jun;105(12):1779-89.
  • Huang CA, Fuchimoto Y, Scheier-Dolberg R, Murphy MC, Neville DM, Sachs DH.
    Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model.
    J Clin Invest. 2000 Jan;105(2):173-81.