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Vikram Deshpande, MBBS


  • Wojcik JB, Bellizzi AM, Dal Cin P, Bredella MA, Fletcher CD, Hornicek FJ, Deshpande V, Hornick JL, Nielsen GP.Primary Sclerosing Epithelioid Fibrosarcoma of Bone: Analysis of a Series.Am J Surg Pathol. 2014 Jun 11.
  • Zhu AX, Borger DR, Kim Y, Cosgrove D, Ejaz A, Alexandrescu S, Groeschl RT, Deshpande V, Lindberg JM, Ferrone C, Sempoux C, Yau T, Poon R, Popescu I, Bauer TW, Gamblin TC, Gigot JF, Anders RA, Pawlik TM.Genomic Profiling of Intrahepatic Cholangiocarcinoma: Refining Prognosis and Identifying Therapeutic Targets.Ann Surg Oncol. 2014 Jun 3.
  • Hong TS, Ryan DP, Borger DR, Blaszkowsky LS, Yeap BY, Ancukiewicz M, Deshpande V, Shinagare S, Wo JY, Boucher Y, Wadlow RC, Kwak EL, Allen JN, Clark JW, Zhu AX, Ferrone CR, Mamon HJ, Adams J, Winrich B, Grillo T, Jain RK, DeLaney TF, Fernandez-Del Castillo C, Duda DG.A Phase 1/2 and Biomarker Study of Preoperative Short Course Chemoradiation With Proton Beam Therapy and Capecitabine Followed By Early Surgery for Resectable Pancreatic Ductal Adenocarcinoma.Int J Radiat Oncol Biol Phys. 2014 May 24.
  • Cipriani NA, Kurzawa P, Ahmad RA, Deshpande V, Hornicek FJ, Mullen JT, Nielsen GP.Prognostic value of myogenic differentiation in undifferentiated pleomorphic sarcomas of soft tissue.Hum Pathol. 2014 Mar 26.
  • Chetty R, Bateman AC, Torlakovic E, Wang LM, Gill P, Al-Badri A, Arends M, Biddlestone L, Burroughs S, Carey F, Cowlishaw D, Crowther S, Da Costa P, Dada MA, d'Adhemar C, Dasgupta K, de Cates C, Deshpande V, Feakins RM, Foria B, Foria V, Fuller C, Green B, Greenson JK, Griffiths P, Hafezi-Bakhtiari S, Henry J, Jaynes E, Jeffers MD, Kaye P, Landers R, Lauwers GY, Loughrey M, Mapstone N, Novelli M, Odze R, Poller D, Rowsell C, Sanders S, Sarsfield P, Schofield JB, Sheahan K, Shepherd N, Sherif A, Sington J, Walsh S, Williams N, Wong N.A pathologist's survey on the reporting of sessile serrated adenomas/polyps.J Clin Pathol. 2014 May;67(5):426-30.
  • Borger DR, Goyal L, Yau T, Poon RT, Ancukiewicz M, Deshpande V, Christiani DC, Liebman HM, Yang H, Kim H, Yen K, Faris JE, Iafrate AJ, Kwak EL, Clark JW, Allen JN, Blaszkowsky LS, Murphy JE, Saha SK, Hong TS, Wo JY, Ferrone CR, Tanabe KK, Bardeesy N, Straley KS, Agresta S, Schenkein DP, Ellisen LW, Ryan DP, Zhu AX.Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma.Clin Cancer Res. 2014 Apr 1;20(7):1884-90.
  • Basturk O, Tang L, Hruban RH, Adsay V, Yang Z, Krasinskas AM, Vakiani E, La Rosa S, Jang KT, Frankel WL, Liu X, Zhang L, Giordano TJ, Bellizzi AM, Chen JH, Shi C, Allen P, Reidy DL, Wolfgang CL, Saka B, Rezaee N, Deshpande V, Klimstra DS.Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases.Am J Surg Pathol. 2014 Apr;38(4):437-47.
  • Deshpande A, Nelson D, Corless CL, Deshpande V, O'Brien MJ.Leiomyoma of the gastrointestinal tract with interstitial cells of Cajal: a mimic of gastrointestinal stromal tumor.Am J Surg Pathol. 2014 Jan;38(1):72-7.
  • Kobraei EM, Song TH, Mathisen DJ, Deshpande V, Mark EJ.Immunoglobulin g4-related disease presenting as an obstructing tracheal mass: consideration of surgical indications.Ann Thorac Surg. 2013 Oct;96(4):e91-3.
  • Wallace ZS, Carruthers MN, Khosroshahi A, Carruthers R, Shinagare S, Stemmer-Rachamimov A, Deshpande V, Stone JH.IgG4-related disease and hypertrophic pachymeningitis.Medicine (Baltimore). 2013 Jul;92(4):206-16.
  • Hu EK, Parrish C, Wrobel B, Deshpande V, Stone JH.Immunoglobulin G4-related disease presenting as an ethmoid and maxillary mass.Ann. Allergy Asthma Immunol. 2013 Jul;111(1):75-7.
  • Tse JY, Wu S, Shinagare SA, Lauwers GY, Yilmaz O, Wu CL, Deshpande V.Peutz-Jeghers syndrome: a critical look at colonic Peutz-Jeghers polyps.Mod Pathol. 2013 Apr 19.
  • Kerr DA, Lopez HU, Deshpande V, Hornicek FJ, Duan Z, Zhang Y, Rosenberg AE, Borger DR, Nielsen GP.Molecular Distinction of Chondrosarcoma From Chondroblastic Osteosarcoma Through IDH1/2 Mutations.Am J Surg Pathol. 2013 Apr 16.
  • Clark CJ, Morales-Oyarvide V, Zaydfudim V, Stauffer J, Deshpande V, Smyrk TC, Chari ST, Fernández-Del Castillo C, Farnell MB.Short-Term and Long-Term Outcomes for Patients with Autoimmune Pancreatitis After Pancreatectomy: A Multi-institutional Study.J Gastrointest Surg. 2013 May;17(5):899-906.
  • Gupta R, Khosroshahi A, Shinagare S, Fernandez C, Ferrone C, Lauwers GY, Stone JH, Deshpande V.Does autoimmune pancreatitis increase the risk of pancreatic carcinoma?: a retrospective analysis of pancreatic resections.Pancreas. 2013 Apr;42(3):506-10.
  • Stone JH, Chan JK, Deshpande V, Okazaki K, Umehara H, Zen Y.IgG4-Related Disease.Int J Rheumatol. 2013;2013:532612.
  • Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE.Genome-wide chromatin state transitions associated with developmental and environmental cues.Cell. 2013 Jan 31;152(3):642-54.
  • Gallotti A, Johnston RP, Bonaffini PA, Ingkakul T, Deshpande V, Fernández-del Castillo C, Sahani DV.Incidental neuroendocrine tumors of the pancreas: MDCT findings and features of malignancy.AJR Am J Roentgenol. 2013 Feb;200(2):355-62.
  • Tzatsos A, Paskaleva P, Ferrari F, Deshpande V, Stoykova S, Contino G, Wong KK, Lan F, Trojer P, Park PJ, Bardeesy N.KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.J Clin Invest. 2013 Jan 16.
  • Chetty R, Gill P, Govender D, Bateman A, Chang HJ, Deshpande V, Driman D, Gomez M, Greywoode G, Jaynes E, Lee CS, Locketz M, Rowsell C, Rullier A, Serra S, Shepherd N, Szentgyorgyi E, Vajpeyi R, Wang LM, Bateman A.International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems.Hum Pathol. 2012 Nov;43(11):1917-23.
  • Fujita H, Lennerz JK, Chung DC, Patel D, Deshpande V, Yoon SS, Lauwers GY.Endoscopic Surveillance of Patients With Hereditary Diffuse Gastric Cancer: Biopsy Recommendations After Topographic Distribution of Cancer Foci in a Series of 10 CDH1-mutated Gastrectomies.Am J Surg Pathol. 2012 Nov;36(11):1709-17.
  • Khor TS, Badizadegan K, Ferrone C, Fernández-Del Castillo C, Desai GS, Saenz A, Le L, Lauwers GY, Deshpande V.Acinar cystadenoma of the pancreas: a clinicopathologic study of 10 cases including multilocular lesions with mural nodules.Am J Surg Pathol. 2012 Nov;36(11):1579-91.
  • Ferry JA, Deshpande V.IgG4-related disease in the head and neck.Semin Diagn Pathol. 2012 Nov;29(4):235-44.
  • Shinagare S, Shinagare AB, Deshpande V.Autoimmune pancreatitis: a guide for the histopathologist.Semin Diagn Pathol. 2012 Nov;29(4):197-204.
  • Deshpande V.The pathology of IgG4-related disease: critical issues and challenges.Semin Diagn Pathol. 2012 Nov;29(4):191-6.
  • Deshpande V.IgG4-related disease. Introduction.Semin Diagn Pathol. 2012 Nov;29(4):175-6.
  • Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S.Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations.Arthritis Rheum. 2012 Oct;64(10):3061-7.
  • Hezel AF, Deshpande V, Zimmerman SM, Contino G, Alagesan B, O'Dell MR, Rivera LB, Harper J, Lonning S, Brekken RA, Bardeesy N.TGF-β and αvβ6 integrin act in a common pathway to suppress pancreatic cancer progression.Cancer Res. 2012 Sep 15;72(18):4840-5.
  • Konstantinidis IT, Warshaw AL, Allen JN, Blaszkowsky LS, Fernandez-Del Castillo C, Deshpande V, Hong TS, Kwak EL, Lauwers GY, Ryan DP, Wargo JA, Lillemoe KD, Ferrone CR.Pancreatic Ductal Adenocarcinoma: Is There a Survival Difference for R1 Resections Versus Locally Advanced Unresectable Tumors? What Is a "True" R0 Resection?.Ann Surg. 2012 Sep 10.
  • Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH.Consensus statement on the pathology of IgG4-related disease.Mod Pathol. 2012 Sep;25(9):1181-92.
  • Wang H, Chen Y, Fernandez-Del Castillo C, Yilmaz O, Deshpande V.Heterogeneity in signaling pathways of gastroenteropancreatic neuroendocrine tumors: a critical look at notch signaling pathway.Mod Pathol. 2012 Aug 24.
  • Ferrone CR, Pieretti-Vanmarcke R, Bloom JP, Zheng H, Szymonifka J, Wargo JA, Thayer SP, Lauwers GY, Deshpande V, Mino-Kenudson M, Fernández-del Castillo C, Lillemoe KD, Warshaw AL.Pancreatic ductal adenocarcinoma: long-term survival does not equal cure.Surgery. 2012 Sep;152(3 Suppl 1):S43-9.
  • Deshpande V, Huck A, Ooi E, Stone JH, Faquin WC, Nielsen GP.Fibrosing variant of Hashimoto thyroiditis is an IgG4 related disease.J Clin Pathol. 2012 Aug;65(8):725-8.
  • Yilmaz ÖH, Katajisto P, Lamming DW, Gültekin Y, Bauer-Rowe KE, Sengupta S, Birsoy K, Dursun A, Yilmaz VO, Selig M, Nielsen GP, Mino-Kenudson M, Zukerberg LR, Bhan AK, Deshpande V, Sabatini DM.mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.Nature. 2012 Jun 28;486(7404):490-5.
  • Mino-Kenudson M, Fernández-Del Castillo C, Baba Y, Valsangkar NP, Liss AS, Hsu M, Correa-Gallego C, Ingkakul T, Johnston RP, Turner BG, Androutsopoulos V, Deshpande V, McGrath D, Sahani DV, Brugge WR, Ogino S, Pitman MB, Warshaw AL, Thayer SP.Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes.Gut. 2011 Jun 10.
  • Le LP, Nielsen GP, Rosenberg AE, Thomas D, Batten JM, Deshpande V, Schwab J, Duan Z, Xavier RJ, Hornicek FJ, Iafrate AJ.Recurrent chromosomal copy number alterations in sporadic chordomas.PLoS ONE. 2011;6(5):e18846.
  • Haynes AB, Deshpande V, Ingkakul T, Vagefi PA, Szymonifka J, Thayer SP, Ferrone CR, Wargo JA, Warshaw AL, Fernández-Del Castillo C.Implications of Incidentally Discovered, Nonfunctioning Pancreatic Endocrine Tumors: Short-term and Long-term Patient Outcomes.Arch Surg. 2011 May;146(5):534-8.
  • Deshpande V, Khosroshahi A, Nielsen GP, Hamilos DL, Stone JH.Eosinophilic angiocentric fibrosis is a form of IgG4-related systemic disease.Am J Surg Pathol. 2011 May;35(5):701-6.
  • Gonzalez-Obeso E, Fujita H, Deshpande V, Ogawa F, Lisovsky M, Genevay M, Grzyb K, Brugge W, Lennerz JK, Shimizu M, Srivastava A, Lauwers GY.Gastric Hyperplastic Polyps: A Heterogeneous Clinicopathologic Group Including a Distinct Subset Best Categorized as Mucosal Prolapse Polyp.Am J Surg Pathol. 2011 Mar 25.
  • Deshpande V, Nduaguba A, Zimmerman SM, Kehoe SM, Macconaill LE, Lauwers GY, Ferrone C, Bardeesy N, Zhu AX, Hezel AF.Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.BMC Cancer. 2011;11:60.
  • Ting DT, Lipson D, Paul S, Brannigan BW, Akhavanfard S, Coffman EJ, Contino G, Deshpande V, Iafrate AJ, Letovsky S, Rivera MN, Bardeesy N, Maheswaran S, Haber DA.Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers.Science. 2011 Feb 4;331(6017):593-6.
  • Demicco EG, Deshpande V, Nielsen GP, Kattapuram SV, Rosenberg AE.Well-differentiated osteosarcoma of the jaw bones: a clinicopathologic study of 15 cases.Am J Surg Pathol. 2010 Nov;34(11):1647-55.
  • Dahlgren M, Khosroshahi A, Nielsen GP, Deshpande V, Stone JH.Riedel's thyroiditis and multifocal fibrosclerosis are part of the IgG4-related systemic disease spectrum.Arthritis Care & Research. 2010 Sep;62(9):1312-8.
  • Farris AB, Lauwers GY, Deshpande V.Autoimmune pancreatitis-related diabetes: quantitative analysis of endocrine islet cells and inflammatory infiltrate.Virchows Arch. 2010 Sep;457(3):329-36.
  • Hezel AF, Deshpande V, Zhu AX.Genetics of biliary tract cancers and emerging targeted therapies.J Clin Oncol. 2010 Jul 20;28(21):3531-40. Review.
  • Khosroshahi A, Bloch DB, Deshpande V, Stone JH.Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4-related systemic disease.Arthritis Rheum. 2010 Jun;62(6):1755-62.
  • Klimstra DS, Modlin IR, Adsay NV, Chetty R, Deshpande V, Gönen M, Jensen RT, Kidd M, Kulke MH, Lloyd RV, Moran C, Moss SF, Oberg K, O'Toole D, Rindi G, Robert ME, Suster S, Tang LH, Tzen CY, Washington MK, Wiedenmann B, Yao J.Pathology reporting of neuroendocrine tumors: application of the Delphic consensus process to the development of a minimum pathology data set.Am J Surg Pathol. 2010 Mar;34(3):300-13.
  • Fritz S,Fernandez-del Castillo C,Mino-Kenudson M,Crippa S,Deshpande V,Lauwers GY,Warshaw AL,Thayer SP,Iafrate AJ.Global genomic analysis of intraductal papillary mucinous neoplasms of the pancreas reveals significant molecular differences compared to ductal adenocarcinoma.Ann Surg. 2009 Mar;249(3):440-7.
  • Plentz R,Park JS,Rhim AD,Abravanel D,Hezel AF,Sharma SV,Gurumurthy S,Deshpande V,Kenific C,Settleman J,Majumder PK,Stanger BZ,Bardeesy N.Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.Gastroenterology. 2009 May;136(5):1741-9.e6.
  • Nikfarjam M, Warshaw AL, Axelrod L, Deshpande V, Thayer SP, Ferrone CR, Fernandez-del Castillo C.Improved contemporary surgical management of insulinomas: a 25-year experience at the Massachusetts General Hospital.Ann Surg. 2008 Jan;247(1):165-72.
  • Finkelberg DL, Sahani D, Deshpande V, Brugge WR.Autoimmune pancreatitis.N Engl J Med. 2006 Dec 21;355(25):2670-6. Review.
  • Deshpande V, Fernandez-del Castillo C, Muzikansky A, Deshpande A, Zukerberg L, Warshaw AL, Lauwers GY.Cytokeratin 19 is a powerful predictor of survival in pancreatic endocrine tumors.Am J Surg Pathol. 2004 Sep;28(9):1145-53.