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Nada Y. Kalaany, PhD


  • Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, White E.Autophagy is Required for Glucose Homeostasis and Lung Tumor Maintenance.Cancer Discovery. 2014 May 29.
  • Curry NL, Mino-Kenudson M, Oliver TG, Yilmaz OH, Yilmaz VO, Moon JY, Jacks T, Sabatini DM, Kalaany NY.Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction.Cancer Discovery. 2013 Aug;3(8):908-21.
  • Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM.Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.Nature. 2011 Jul 14.
  • Kalaany NY, Sabatini DM.Tumours with PI3K activation are resistant to dietary restriction.Nature. 2009 Apr 9;458(7239):725-31.
  • Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM.Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.Dev Cell. 2006 Dec;11(6):859-71.
  • Kalaany NY, Mangelsdorf DJ.LXRS and FXR: the yin and yang of cholesterol and fat metabolism.Annu Rev Physiol. 2006;68:159-91. Review.
  • Kalaany NY, Gauthier KC, Zavacki AM, Mammen PP, Kitazume T, Peterson JA, Horton JD, Garry DJ, Bianco AC, Mangelsdorf DJ.LXRs regulate the balance between fat storage and oxidation.Cell Metab. 2005 Apr;1(4):231-44.
  • El-Sabban ME, Sfeir AJ, Daher MH, Kalaany NY, Bassam RA, Talhouk RS.ECM-induced gap junctional communication enhances mammary epithelial cell differentiation.J Cell Sci. 2003 Sep 1;116(Pt 17):3531-41.