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Michael J. Kluk, MD, PhD

Publications

  • South AP, Purdie KJ, Watt SA, Haldenby S, den Breems NY, Dimon M, Arron ST, Kluk MJ, Aster JC, McHugh A, Xue DJ, Dayal JH, Robinson KS, Rizvi SM, Proby CM, Harwood CA, Leigh IM.NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis.J Invest Dermatol. 2014 Mar 24.
    24662767
  • Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE.An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.Nat Genet. 2014 Apr;46(4):364-70.
    24584072
  • Zhang G, Yang L, Kim GS, Ryan K, Lu S, O'Donnell RK, Spokes K, Shapiro N, Aird WC, Kluk MJ, Yano K, Sanchez T.Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation.Blood. 2013 Jul 18;122(3):443-55.
    23723450
  • Kluk MJ, Ashworth T, Wang H, Knoechel B, Mason EF, Morgan EA, Dorfman D, Pinkus G, Weigert O, Hornick JL, Chirieac LR, Hirsch M, Oh DJ, South AP, Leigh IM, Pourreyron C, Cassidy AJ, Deangelo DJ, Weinstock DM, Krop IE, Dillon D, Brock JE, Lazar AJ, Peto M, Cho RJ, Stoeck A, Haines BB, Sathayanrayanan S, Rodig S, Aster JC.Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry.PLoS ONE. 2013;8(6):e67306.
    23825651
  • Kluk MJ, Ryan KP, Wang B, Zhang G, Rodig SJ, Sanchez T.Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration.Lab Invest. 2013 Apr;93(4):462-71.
    23419711
  • Kluk MJ, Chapuy B, Sinha P, Roy A, Dal Cin P, Neuberg DS, Monti S, Pinkus GS, Shipp MA, Rodig SJ.Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas.PLoS ONE. 2012;7(4):e33813.
    22511926
  • Kluk MJ and Hla T.Role of the sphingosine-1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.Circ Res..