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Anyong Xie, PhD


  • Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W.
    Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.
    Mol Cell. 2015 Feb 19;57(4):648-61.
  • Chandramouly G, Kwok A, Huang B, Willis NA, Xie A, Scully R.
    BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.
    Nat Commun. 2013;4:2404.
  • Rass E, Chandramouly G, Zha S, Alt FW, Xie A.
    Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.
    J Biol Chem. 2013 Mar 8;288(10):7086-95.
  • Hartlerode AJ, Guan Y, Rajendran A, Ura K, Schotta G, Xie A, Shah JV, Scully R.
    Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks.
    PLoS ONE. 2012;7(11):e49211.
  • Nguyen CL, Possemato R, Bauerlein EL, Xie A, Scully R, Hahn WC.
    Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts.
    Mol Cell Biol. 2012 Oct;32(19):3963-77.
  • Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM.
    RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci.
    Genes Dev. 2011 Apr 1;25(7):685-700.
  • Xie A, Odate S, Chandramouly G, Scully R.
    H2AX post-translational modifications in the ionizing radiation response and homologous recombination.
    Cell Cycle. 2010 Sep;9(17):3602-10.
  • Xie A, Kwok A, Scully R.
    Role of mammalian Mre11 in classical and alternative nonhomologous end joining.
    Nat Struct Mol Biol. 2009 Aug;16(8):814-8.
  • Xie A,Hartlerode A,Stucki M,Odate S,Puget N,Kwok A,Nagaraju G,Yan C,Alt FW,Chen J,Jackson SP,Scully R.
    Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.
    Mol Cell. 2007 Dec 28;28(6):1045-57.
  • Nagaraju G, Odate S, Xie A, Scully R.
    Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C.
    Mol Cell Biol. 2006 Nov;26(21):8075-86.
  • Xie A, Puget N, Shim I, Odate S, Jarzyna I, Bassing CH, Alt FW, Scully R.
    Control of sister chromatid recombination by histone H2AX.
    Mol Cell. 2004 Dec 22;16(6):1017-25.
  • Scully R, Xie A.
    BRCA1 and BRCA2 in breast cancer predisposition and recombination control.
    J Mammary Gland Biol Neoplasia. 2004 Jul;9(3):237-46.
  • Scully R, Xie A, Nagaraju G.
    Molecular functions of BRCA1 in the DNA damage response.
    Cancer Biol Ther. 2004 Jun;3(6):521-7.