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Laurence A. Turka, MD


  • Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, Ito K, Turka LA, Beck AH, Pinton P, Bronson RT, Wei W, Pandolfi PP.Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function.Cell. 2014 Apr 24;157(3):595-610.
  • Huynh A, Zhang R, Turka LA.Signals and pathways controlling regulatory T cells.Immunol Rev. 2014 Mar;258(1):117-31.
  • Yeung MY, McGrath MM, Nakayama M, Shimizu T, Boenisch O, Magee CN, Abdoli R, Akiba H, Ueno T, Turka LA, Najafian N.Interruption of dendritic cell-mediated TIM-4 signaling induces regulatory T cells and promotes skin allograft survival.J Immunol. 2013 Oct 15;191(8):4447-55.
  • Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, Wu GD, Choi Y.Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.Immunity. 2013 Jun 27;38(6):1211-22.
  • Zhang R, Huynh A, Whitcher G, Chang J, Maltzman JS, Turka LA.An obligate cell-intrinsic function for CD28 in Tregs.J Clin Invest. 2013 Feb 1;123(2):580-93.
  • Huynh A, Turka LA.Control of T cell tolerance by phosphatase and tensin homolog.Ann N Y Acad Sci. 2013 Mar;1280(1):27-9.
  • Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH.MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling.Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2270-5.
  • Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, Harris TH, Grainger J, Wojno ED, Wagage S, Roos DS, Scott P, Turka LA, Cherry S, Reiner SL, Cua D, Belkaid Y, Elloso MM, Hunter CA.The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.Immunity. 2012 Sep 21;37(3):511-23.
  • Gupta S, Thornley TB, Gao W, Larocca R, Turka LA, Kuchroo VK, Strom TB.Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs.J Clin Invest. 2012 Jul 2;122(7):2395-404.
  • Newton RH, Turka LA.Regulation of T cell homeostasis and responses by pten.Frontiers In Immunology. 2012;3:151.
  • Lieberman SM, Kim JS, Corbo-Rodgers E, Kambayashi T, Maltzman JS, Behrens EM, Turka LA.Site-specific accumulation of recently activated CD4+ Foxp3+ regulatory T cells following adoptive transfer.Eur J Immunol. 2012 Jun;42(6):1429-35.
  • Liu X, Karnell JL, Yin B, Zhang R, Zhang J, Li P, Choi Y, Maltzman JS, Pear WS, Bassing CH, Turka LA.Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice.J Clin Invest. 2010 Jul 1;120(7):2497-507.