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Nathan McDannold, PhD


  • Aryal M, Vykhodtseva N, Zhang YZ, McDannold N.
    Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood-brain barrier disruption: A safety study.
    J Control Release. 2015 Apr 28;204:60-9.
  • Aryal M, Park J, Vykhodtseva N, Zhang YZ, McDannold N.
    Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model.
    Phys Med Biol. 2015 Mar 21;60(6):2511-27.
  • Kopechek JA, Park EJ, Zhang YZ, Vykhodtseva NI, McDannold NJ, Porter TM.
    Cavitation-enhanced MR-guided focused ultrasound ablation of rabbit tumors in vivo using phase shift nanoemulsions.
    Phys Med Biol. 2014 Jul 7;59(13):3465-81.
  • Aryal M, Arvanitis CD, Alexander PM, McDannold N.
    Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system.
    Adv Drug Deliv Rev. 2014 Jan 22.
  • Jolesz FA, McDannold NJ.
    Magnetic resonance-guided focused ultrasound: a new technology for clinical neurosciences.
    Neurol Clin. 2014 Feb;32(1):253-69.
  • Arvanitis CD, Livingstone MS, McDannold N.
    Combined ultrasound and MR imaging to guide focused ultrasound therapies in the brain.
    Phys Med Biol. 2013 Jul 21;58(14):4749-61.
  • Aryal M, Vykhodtseva N, Zhang YZ, Park J, McDannold N.
    Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improves outcomes in a rat glioma model.
    J Control Release. 2013 Apr 18.
  • Kopechek JA, Park E, Mei CS, McDannold NJ, Porter TM.
    Accumulation of phase-shift nanoemulsions to enhance MR-guided ultrasound-mediated tumor ablation in vivo.
    J Healthc Eng. 2013;4(1):109-26.
  • Park EJ, Zhang YZ, Vykhodtseva N, McDannold N.
    Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model.
    J Control Release. 2012 Nov 10;163(3):277-84.
  • Treat LH, McDannold N, Zhang Y, Vykhodtseva N, Hynynen K.
    Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma.
    Ultrasound Med Biol. 2012 Oct;38(10):1716-25.
  • Park J, Zhang Y, Vykhodtseva N, Jolesz FA, McDannold NJ.
    The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound.
    J Control Release. 2012 Aug 20;162(1):134-42.
  • McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS.
    Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques.
    Cancer Res. 2012 Jul 15;72(14):3652-63.
  • McDannold N, Clement GT, Black P, Jolesz F, Hynynen K.
    Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients.
    Neurosurgery. 2010 Feb;66(2):323-32; discussion 332.
  • McDannold N, Vykhodtseva N, Hynynen K.
    Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index.
    Ultrasound Med Biol. 2008 May;34(5):834-40.