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Edward C. Stack, PhD

Publications

  • Norden AD, Lesser GJ, Drappatz J, Ligon KL, Hammond SN, Lee EQ, Reardon DR, Fadul CE, Plotkin SR, Batchelor TT, Zhu JJ, Beroukhim R, Muzikansky A, Doherty L, Lafrankie D, Smith K, Tafoya V, Lis R, Stack EC, Rosenfeld MR, Wen PY.Phase 2 study of dose-intense temozolomide in recurrent glioblastoma.Neuro Oncology. 2013 Apr 3.
    23553268
  • Jia S, Gao X, Lee SH, Maira SM, Wu X, Stack EC, Signoretti S, Loda M, Zhao JJ, Roberts TM.Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.Cancer Discovery. 2013 Jan;3(1):44-51.
    23258246
  • Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M.EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.Science. 2012 Dec 14;338(6113):1465-9.
    23239736
  • Grisanzio C, Werner L, Takeda D, Awoyemi BC, Pomerantz MM, Yamada H, Sooriakumaran P, Robinson BD, Leung R, Schinzel AC, Mills I, Ross-Adams H, Neal DE, Kido M, Yamamoto T, Petrozziello G, Stack EC, Lis R, Kantoff PW, Loda M, Sartor O, Egawa S, Tewari AK, Hahn WC, Freedman ML.Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11252-7.
    22730461
  • Pettersson A, Graff RE, Bauer SR, Pitt MJ, Lis RT, Stack EC, Martin NE, Kunz L, Penney KL, Ligon A, Suppan C, Flavin R, Sesso H, Rider JR, Sweeney CS, Stampfer MJ, Fiorentino M, Kantoff PW, Sanda MG, Giovannucci E, Ding EL, Loda M, Mucci LA.The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: a Cohort Study and Meta-analysis.Cancer Epidemiol Biomarkers Prev. 2012 Jun 26.
    22736790
  • Sullivan CP, Jay AG, Stack EC, Pakaluk M, Wadlinger E, Fine RE, Wells JM, Morin PJ.Retromer disruption promotes amyloidogenic APP processing.Neurobiol Dis. 2011 Aug;43(2):338-45.
    21515373
  • Stack EC, Desarnaud F, Siwek DF, Datta S.A novel role for calcium/calmodulin kinase II within the brainstem pedunculopontine tegmentum for the regulation of wakefulness and rapid eye movement sleep.J Neurochem. 2010 Jan;112(1):271-81.
    19860859
  • Del Signore SJ, Amante DJ, Kim J, Stack EC, Goodrich S, Cormier K, Smith K, Cudkowicz ME, Ferrante RJ.Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice.Amyotrophic Lateral Sclerosis : Official Publication Of The World Federation Of Neurology Research Group On Motor Neuron Diseases. 2009 Apr;10(2):85-94.
    18618304
  • Stack EC, Matson WR, Ferrante RJ.Evidence of oxidant damage in Huntington's disease: translational strategies using antioxidants.Ann N Y Acad Sci. 2008 Dec;1147:79-92. Review.
    19076433
  • Stack EC, Ferro JL, Kim J, Del Signore SJ, Goodrich S, Matson S, Hunt BB, Cormier K, Smith K, Matson WR, Ryu H, Ferrante RJ.Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease.Biochim Biophys Acta. 2008 Mar;1782(3):151-62.
    18206128
  • Stack EC, Ferrante RJ.Huntington's disease: progress and potential in the field.Expert Opin Investig Drugs. 2007 Dec;16(12):1933-53. Review.
    18042002
  • Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ.Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.J Neurosci. 2007 Nov 21;27(47):12908-15.
    18032664
  • Stack EC, Del Signore SJ, Luthi-Carter R, Soh BY, Goldstein DR, Matson S, Goodrich S, Markey AL, Cormier K, Hagerty SW, Smith K, Ryu H, Ferrante RJ.Modulation of nucleosome dynamics in Huntington's disease.Hum Mol Genet. 2007 May 15;16(10):1164-75.
    17403718
  • Smith KM, Matson S, Matson WR, Cormier K, Del Signore SJ, Hagerty SW, Stack EC, Ryu H, Ferrante RJ.Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice.Biochim Biophys Acta. 2006 Jun;1762(6):616-26.
    16647250
  • Stack EC, Smith KM, Ryu H, Cormier K, Chen M, Hagerty SW, Del Signore SJ, Cudkowicz ME, Friedlander RM, Ferrante RJ.Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice.Biochim Biophys Acta. 2006 Mar;1762(3):373-80.
    16364609
  • Stack EC, Kubilus JK, Smith K, Cormier K, Del Signore SJ, Guelin E, Ryu H, Hersch SM, Ferrante RJ.Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.J Comp Neurol. 2005 Oct 3;490(4):354-70.
    16127709
  • Fink JS, Kalda A, Ryu H, Stack EC, Schwarzschild MA, Chen JF, Ferrante RJ.Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage.J Neurochem. 2004 Feb;88(3):538-44.
    14720203
  • Stack EC, Balakrishnan R, Numan MJ, Numan M.A functional neuroanatomical investigation of the role of the medial preoptic area in neural circuits regulating maternal behavior.Behav Brain Res. 2002 Apr 1;131(1-2):17-36.
    11844569