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Maria Kontaridis, PhD

Publications

  • Marin TM, Keith K, Davies B, Conner DA, Guha P, Kalaitzidis D, Wu X, Lauriol J, Wang B, Bauer M, Bronson R, Franchini KG, Neel BG, Kontaridis MI.Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.J Clin Invest. 2011 Mar;121(3):1026-43.
    21339643
  • Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG.Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.Dev Cell. 2010 May 18;18(5):750-62.
    20493809
  • Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG.Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.Circulation. 2008 Mar 18;117(11):1423-35.
    18316486
  • Kontaridis MI, Swanson KD, David FS, Barford D, Neel BG.PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects.J Biol Chem. 2006 Mar 10;281(10):6785-92.
    16377799