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Dennis C. Sgroi, MD

Publications

  • Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Tenorio GP, Fornander T, Sgroi DC, Garcia-Mata R, Jansen MP, García N, Bonifaci N, Climent F, Soler MT, Rodríguez-Vida A, Gil M, Brunet J, Martrat G, Gómez-Baldó L, Extremera AI, Figueras A, Balart J, Clarke R, Burnstein KL, Carlson KE, Katzenellenbogen JA, Vizoso M, Esteller M, Villanueva A, Rodríguez-Peña AB, Bustelo XR, Nakamura Y, Zembutsu H, Stål O, Beijersbergen RL, Pujana MA.VAV3 mediates resistance to breast cancer endocrine therapy.Breast Cancer Res. 2014 May 28;16(3):R53.
    24886537
  • Sjöström M, Hartman L, Grabau D, Fornander T, Malmström P, Nordenskjöld B, Sgroi DC, Skoog L, Stål O, Leeb-Lundberg LM, Fernö M.Lack of G protein-coupled estrogen receptor (GPER) in the plasma membrane is associated with excellent long-term prognosis in breast cancer.Breast Cancer Res Treat. 2014 May;145(1):61-71.
    24715381
  • McMullin RP, Wittner BS, Yang C, Denton-Schneider BR, Hicks D, Singavarapu R, Moulis S, Lee J, Akbari MR, Narod SA, Aldape KD, Steeg PS, Ramaswamy S, Sgroi DC.A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.Breast Cancer Res. 2014 Mar 14;16(2):R25.
    24625110
  • Wong JS, Chen YH, Gadd MA, Gelman R, Lester SC, Schnitt SJ, Sgroi DC, Silver BJ, Smith BL, Troyan SL, Harris JR.Eight-year update of a prospective study of wide excision alone for small low- or intermediate-grade ductal carcinoma in situ (DCIS).Breast Cancer Res Treat. 2014 Jan;143(2):343-50.
    24346130
  • Sgroi DC, Sestak I, Cuzick J, Zhang Y, Schnabel CA, Schroeder B, Erlander MG, Dunbier A, Sidhu K, Lopez-Knowles E, Goss PE, Dowsett M.Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.Lancet Oncol. 2013 Oct;14(11):1067-76.
    24035531
  • Sgroi DC, Carney E, Zarrella E, Steffel L, Binns SN, Finkelstein DM, Szymonifka J, Bhan AK, Shepherd LE, Zhang Y, Schnabel CA, Erlander MG, Ingle JN, Porter P, Muss HB, Pritchard KI, Tu D, Rimm DL, Goss PE.Prediction of late disease recurrence and extended adjuvant letrozole benefit by the HOXB13/IL17BR biomarker.Journal of the National Cancer Institute. 2013 Jul 17;105(14):1036-42.
    23812955
  • Price JC, Pollock LM, Rudd ML, Fogoros SK, Mohamed H, Hanigan CL, Le Gallo M, Program NI, Zhang S, Cruz P, Cherukuri PF, Hansen NF, McManus KJ, Godwin AK, Sgroi DC, Mullikin JC, Merino MJ, Hieter P, Bell DW.Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A.PLoS ONE. 2013;8(6):e63313.
    23755103
  • Weiner M, Skoog L, Fornander T, Nordenskjöld B, Sgroi DC, Stål O.Oestrogen receptor co-activator AIB1 is a marker of tamoxifen benefit in postmenopausal breast cancer.Ann Oncol. 2013 May 12.
    23670096
  • Le Gallo M, O'Hara AJ, Rudd ML, Urick ME, Hansen NF, O'Neil NJ, Price JC, Zhang S, England BM, Godwin AK, Sgroi DC, , Hieter P, Mullikin JC, Merino MJ, Bell DW.Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.Nat Genet. 2012 Oct 28.
    23104009
  • Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, Bautista-Piña V, Duke F, Francis J, Jung J, Maffuz-Aziz A, Onofrio RC, Parkin M, Pho NH, Quintanar-Jurado V, Ramos AH, Rebollar-Vega R, Rodriguez-Cuevas S, Romero-Cordoba SL, Schumacher SE, Stransky N, Thompson KM, Uribe-Figueroa L, Baselga J, Beroukhim R, Polyak K, Sgroi DC, Richardson AL, Jimenez-Sanchez G, Lander ES, Gabriel SB, Garraway LA, Golub TR, Melendez-Zajgla J, Toker A, Getz G, Hidalgo-Miranda A, Meyerson M.Sequence analysis of mutations and translocations across breast cancer subtypes.Nature. 2012 Jun 21;486(7403):405-9.
    22722202
  • Rudd ML, Price JC, Fogoros S, Godwin AK, Sgroi DC, Merino MJ, Bell DW.A Unique Spectrum of Somatic PIK3CA (p110{alpha}) Mutations Within Primary Endometrial Carcinomas.Clin Cancer Res. 2011 Mar 15;17(6):1331-40.
    21266528
  • Yang C, Hayashida T, Forster N, Li C, Shen D, Maheswaran S, Chen L, Anderson KS, Ellisen LW, Sgroi D, Schmidt EV.The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.Cancer Res. 2011 Feb 1;71(3):937-45.
    21127199
  • Bombonati A, Sgroi DC.The molecular pathology of breast cancer progression.J Pathol. 2011 Jan;223(2):307-17. Review.
    21125683
  • Tung N, Miron A, Schnitt SJ, Gautam S, Fetten K, Kaplan J, Yassin Y, Buraimoh A, Kim JY, Szasz AM, Tian R, Wang ZC, Collins LC, Brock J, Krag K, Legare RD, Sgroi D, Ryan PD, Silver D, Garber JE, Richardson AL.Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancers.Breast Cancer Res. 2010 Nov 16;12(6):R95.
    21080930
  • Cha S, Imielinski MB, Rejtar T, Richardson EA, Thakur D, Sgroi DC, Karger BL.In Situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection (LCM)-LC/MS: Annotation by protein set enrichment analysis (PSEA) and gene ontology (GO).Mol Cell Proteomics. 2010 Nov;9(11):2529-44.
    20739354
  • Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA.A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.Cancer Res. 2010 Mar 15;70(6):2158-64.
    20215515
  • Tung N, Wang Y, Collins LC, Kaplan J, Li H, Gelman R, Comander AH, Gallagher B, Fetten K, Krag K, Stoeckert KA, Legare RD, Sgroi D, Ryan PD, Garber JE, Schnitt SJ.Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic features.Breast Cancer Res. 2010 Feb 11;12(1):R12.
    20149218
  • Horak P, Crawford AR, Vadysirisack DD, Nash ZM, DeYoung MP, Sgroi D, Ellisen LW.Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis.Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4675-80.
    20176937
  • Silver DP, Richardson AL, Eklund AC, Wang ZC, Szallasi Z, Li Q, Juul N, Leong CO, Calogrias D, Buraimoh A, Fatima A, Gelman RS, Ryan PD, Tung NM, De Nicolo A, Ganesan S, Miron A, Colin C, Sgroi DC, Ellisen LW, Winer EP, Garber JE.Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer.J Clin Oncol. 2010 Mar 1;28(7):1145-53.
    20100965
  • Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, Gross KW, Vivanco MM, Wijendran V, Shioda T, Sgroi D, Donahoe PK, Maheswaran S.HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1100-5.
    20080567
  • Sgroi DC.Preinvasive breast cancer.Annu Rev Pathol. 2010;5:193-221. Review.
    19824828
  • Zhang J, Song YH, Brannigan BW, Wahrer DC, Schiripo TA, Harris PL, Haserlat SM, Ulkus LE, Shannon KM, Garber JE, Freedman ML, Henderson BE, Zou L, Sgroi DC, Haber DA, Bell DW.Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin.Mol Cancer Res. 2009 Sep;7(9):1510-6.
    19737971
  • Willers H, Taghian AG, Luo CM, Treszezamsky A, Sgroi DC, Powell SN.Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies.Mol Cancer Res. 2009 Aug;7(8):1304-9.
    19671671
  • Burstein HJ, Souter I, D'Alessandro HA, Sgroi DC.Case records of the Massachusetts General Hospital. Case 25-2009. A 36-year-old woman with hormone-receptor-positive breast cancer.N Engl J Med. 2009 Aug 13;361(7):699-707.
    19675333
  • Sgroi DC.Breast cancer SRC activity: bad to the bone.Cancer Cell. 2009 Jul 7;16(1):1-2.
    19573804
  • Marselli L, Sgroi DC, Bonner-Weir S, Weir GC.Laser Capture Microdissection of Human Pancreatic beta-Cells and RNA Preparation for Gene Expression Profiling.Methods Mol Biol. 2009;560:87-98.
    19504246
  • Ma XJ,Dahiya S,Richardson E,Erlander M,Sgroi DC.Gene expression profiling of the tumor microenvironment during breast cancer progression.Breast Cancer Res. 2009;11(1):R7.
    19187537
  • Goetz MP,Suman VJ,Couch FJ,Ames MM,Rae JM,Erlander MG,Ma XJ,Sgroi DC,Reynolds CA,Lingle WL,Weinshilboum RM,Flockhart DA,Desta Z,Perez EA,Ingle JN.Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance.Clin Cancer Res. 2008 Sep 15;14(18):5864-8.
    18794098
  • Ince TA,Ward JM,Valli VE,Sgroi D,Nikitin AY,Loda M,Griffey SM,Crum CP,Crawford JM,Bronson RT,Cardiff RD.Do-it-yourself (DIY) pathology.Nat Biotechnol. 2008 Sep;26(9):978-9; discussion 979.
    18779800
  • Hao J,Serohijos AW,Newton G,Tassone G,Wang Z,Sgroi DC,Dokholyan NV,Basilion JP.Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers.PLoS Comput Biol. 2008;4(8):e1000138.
    18670594
  • Maeder ML,Thibodeau-Beganny S,Osiak A,Wright DA,Anthony RM,Eichtinger M,Jiang T,Foley JE,Winfrey RJ,Townsend JA,Unger-Wallace E,Sander JD,Muller-Lerch F,Fu F,Pearlberg J,Gobel C,Dassie JP,Pruett-Miller SM,Porteus MH,Sgroi DC,Iafrate AJ,Dobbs D,McCray PB Jr,Cathomen T,Voytas DF,Joung JK.Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.Mol Cell. 2008 Jul 25;31(2):294-301.
    18657511
  • Wittner BS,Sgroi DC,Ryan PD,Bruinsma TJ,Glas AM,Male A,Dahiya S,Habin K,Bernards R,Haber DA,Van't Veer LJ,Ramaswamy S.Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort.Clin Cancer Res. 2008 May 15;14(10):2988-93.
    18483364
  • Ma XJ, Salunga R, Dahiya S, Wang W, Carney E, Durbecq V, Harris A, Goss P, Sotiriou C, Erlander M, Sgroi D.A Five-Gene Molecular Grade Index and HOXB13:IL17BR Are Complementary Prognostic Factors in Early Stage Breast Cancer.Clin Cancer Res. 2008 May 1;14(9):2601-8.
    18451222
  • Moulis S, Sgroi DC.Re-evaluating early breast neoplasia.Breast Cancer Res. 2008;10(1):302.
    18279539
  • DeYoung MP, Horak P, Sofer A, Sgroi D, Ellisen LW.Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling.Genes Dev. 2008 Jan 15;22(2):239-51.
    18198340
  • Wang Z, Dahiya S, Provencher H, Muir B, Carney E, Coser K, Shioda T, Ma XJ, Sgroi DC.The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer.Clin Cancer Res. 2007 Nov 1;13(21):6327-34.
    17975144
  • Miao J, Wang Z, Provencher H, Muir B, Dahiya S, Carney E, Leong CO, Sgroi DC, Orsulic S.HOXB13 promotes ovarian cancer progression.Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17093-8.
    17942676
  • Bell DW, Kim SH, Godwin AK, Schiripo TA, Harris PL, Haserlat SM, Wahrer DC, Haiman CA, Daly MB, Niendorf KB, Smith MR, Sgroi DC, Garber JE, Olopade OI, Le Marchand L, Henderson BE, Altshuler D, Haber DA, Freedman ML.Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.Int J Cancer. 2007 Dec 15;121(12):2661-7.
    17721994
  • Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA.A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors.Genes Dev. 2007 Sep 1;21(17):2131-6.
    17704304
  • Moran ST, Cariappa A, Liu H, Muir B, Sgroi D, Boboila C, Pillai S.Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes.J Immunol. 2007 Jul 1;179(1):195-200.
    17579038
  • Leong CO, Vidnovic N, Deyoung MP, Sgroi D, Ellisen LW.The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers.J Clin Invest. 2007 May;117(5):1370-80.
    17446929
  • Harris LN, You F, Schnitt SJ, Witkiewicz A, Lu X, Sgroi D, Ryan PD, Come SE, Burstein HJ, Lesnikoski BA, Kamma M, Friedman PN, Gelman R, Iglehart JD, Winer EP.Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer.Clin Cancer Res. 2007 Feb 15;13(4):1198-207.
    17317830
  • Frackelton AR, Lu L, Davol PA, Bagdasaryan R, Hafer LJ, Sgroi DC.p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy.Breast Cancer Res. 2006;8(6):R73.
    17196107
  • Yang C, Trent S, Ionescu-Tiba V, Lan L, Shioda T, Sgroi D, Schmidt EV.Identification of cyclin D1- and estrogen-regulated genes contributing to breast carcinogenesis and progression.Cancer Res. 2006 Dec 15;66(24):11649-58.
    17178859
  • Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA.The Spemann organizer gene, Goosecoid, promotes tumor metastasis.Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18969-74.
    17142318
  • Ma XJ, Hilsenbeck SG, Wang W, Ding L, Sgroi DC, Bender RA, Osborne CK, Allred DC, Erlander MG.The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer.J Clin Oncol. 2006 Oct 1;24(28):4611-9.
    17008703
  • Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA.Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon.Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12405-10.
    16894141
  • Kwak EL, Jankowski J, Thayer SP, Lauwers GY, Brannigan BW, Harris PL, Okimoto RA, Haserlat SM, Driscoll DR, Ferry D, Muir B, Settleman J, Fuchs CS, Kulke MH, Ryan DP, Clark JW, Sgroi DC, Haber DA, Bell DW.Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas.Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4283-7.
    16857803
  • Goetz MP, Suman VJ, Ingle JN, Nibbe AM, Visscher DW, Reynolds CA, Lingle WL, Erlander M, Ma XJ, Sgroi DC, Perez EA, Couch FJ.A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen.Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2080-7.
    16609019
  • Smolen GA, Muir B, Mohapatra G, Barmettler A, Kim WJ, Rivera MN, Haserlat SM, Okimoto RA, Kwak E, Dahiya S, Garber JE, Bell DW, Sgroi DC, Chin L, Deng CX, Haber DA.Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis.Cancer Res. 2006 Apr 1;66(7):3452-5.
    16585167
  • Wong JS, Kaelin CM, Troyan SL, Gadd MA, Gelman R, Lester SC, Schnitt SJ, Sgroi DC, Silver BJ, Harris JR, Smith BL.Prospective study of wide excision alone for ductal carcinoma in situ of the breast.J Clin Oncol. 2006 Mar 1;24(7):1031-6.
    16461781
  • Smolen GA, Sordella R, Muir B, Mohapatra G, Barmettler A, Archibald H, Kim WJ, Okimoto RA, Bell DW, Sgroi DC, Christensen JG, Settleman J, Haber DA.Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2316-21.
    16461907
  • Gunawardane RN, Sgroi DC, Wrobel CN, Koh E, Daley GQ, Brugge JS.Novel role for PDEF in epithelial cell migration and invasion.Cancer Res. 2005 Dec 15;65(24):11572-80.
    16357167
  • Michaelson JS, Cheongsiatmoy JA, Dewey F, Silverstein MJ, Sgroi D, Smith B, Tanabe KK.Spread of human cancer cells occurs with probabilities indicative of a nongenetic mechanism.Br J Cancer. 2005 Nov 28;93(11):1244-9.
    16278668
  • Bell DW, Lynch TJ, Haserlat SM, Harris PL, Okimoto RA, Brannigan BW, Sgroi DC, Muir B, Riemenschneider MJ, Iacona RB, Krebs AD, Johnson DH, Giaccone G, Herbst RS, Manegold C, Fukuoka M, Kris MG, Baselga J, Ochs JS, Haber DA.Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials.J Clin Oncol. 2005 Nov 1;23(31):8081-92.
    16204011
  • Collins NL, Reginato MJ, Paulus JK, Sgroi DC, Labaer J, Brugge JS.G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression.Mol Cell Biol. 2005 Jun;25(12):5282-91.
    15923641
  • Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, Fuller A, Muir B, Mohapatra G, Salunga R, Tuggle JT, Tran Y, Tran D, Tassin A, Amon P, Wang W, Wang W, Enright E, Stecker K, Estepa-Sabal E, Smith B, Younger J, Balis U, Michaelson J, Bhan A, Habin K, Baer TM, Brugge J, Haber DA, Erlander MG, Sgroi DC.A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen.Cancer Cell. 2004 Jun;5(6):607-16.
    15193263
  • Yang C, Ionescu-Tiba V, Burns K, Gadd M, Zukerberg L, Louis DN, Sgroi D, Schmidt EV.The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.Am J Pathol. 2004 Mar;164(3):1031-8.
    14982856
  • Michaelson JS, Silverstein M, Sgroi D, Cheongsiatmoy JA, Taghian A, Powell S, Hughes K, Comegno A, Tanabe KK, Smith B.The effect of tumor size and lymph node status on breast carcinoma lethality.Cancer. 2003 Nov 15;98(10):2133-43.
    14601082
  • Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS.Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis.Nat Cell Biol. 2003 Aug;5(8):733-40.
    12844146
  • Ma XJ, Salunga R, Tuggle JT, Gaudet J, Enright E, McQuary P, Payette T, Pistone M, Stecker K, Zhang BM, Zhou YX, Varnholt H, Smith B, Gadd M, Chatfield E, Kessler J, Baer TM, Erlander MG, Sgroi DC.Gene expression profiles of human breast cancer progression.Proc Natl Acad Sci U S A. 2003 May 13;100(10):5974-9.
    12714683
  • Talora C, Sgroi DC, Crum CP, Dotto GP.Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation.Genes Dev. 2002 Sep 1;16(17):2252-63.
    12208848
  • Bell DW, Erban J, Sgroi DC, Haber DA.Selective loss of heterozygosity in multiple breast cancers from a carrier of mutations in both BRCA1 and BRCA2.Cancer Res. 2002 May 15;62(10):2741-3.
    12019146
  • Enerbck C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, Polyak K.Psoriasin expression in mammary epithelial cells in vitro and in vivo.Cancer Res. 2002 Jan 1;62(1):43-7.
    11782356
  • Lee SB, Kim SH, Bell DW, Wahrer DC, Schiripo TA, Jorczak MM, Sgroi DC, Garber JE, Li FP, Nichols KE, Varley JM, Godwin AK, Shannon KM, Harlow E, Haber DA.Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome.Cancer Res. 2001 Nov 15;61(22):8062-7.
    11719428
  • Porter DA, Krop IE, Nasser S, Sgroi D, Kaelin CM, Marks JR, Riggins G, Polyak K.A SAGE (serial analysis of gene expression) view of breast tumor progression.Cancer Res. 2001 Aug 1;61(15):5697-702.
    11479200
  • Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K.HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9796-801.
    11481438
  • Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.Cell. 2001 Apr 6;105(1):149-60.
    11301010
  • Sgroi DC, Teng S, Robinson G, LeVangie R, Hudson JR, Elkahloun AG.In vivo gene expression profile analysis of human breast cancer progression.Cancer Res. 1999 Nov 15;59(22):5656-61.
    10582678
  • Barnes YC, Skelton TP, Stamenkovic I, Sgroi DC.Sialylation of the sialic acid binding lectin sialoadhesin regulates its ability to mediate cell adhesion.Blood. 1999 Feb 15;93(4):1245-52.
    9949167
  • Sgroi D, Nocks A, Stamenkovic I.A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33.J Biol Chem. 1996 Aug 2;271(31):18803-9.
    8702538
  • FitzGerald MG, MacDonald DJ, Krainer M, Hoover I, O'Neil E, Unsal H, Silva-Arrieto S, Finkelstein DM, Beer-Romero P, Englert C, Sgroi DC, Smith BL, Younger JW, Garber JE, Duda RB, Mayzel KA, Isselbacher KJ, Friend SH, Haber DA.Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer.N Engl J Med. 1996 Jan 18;334(3):143-9.
    8531968
  • Sgroi D, Koretzky GA, Stamenkovic I.Regulation of CD45 engagement by the B-cell receptor CD22.Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4026-30.
    7537381
  • Xu L, Sgroi D, Sterner CJ, Beauchamp RL, Pinney DM, Keel S, Ueki K, Rutter JL, Buckler AJ, Louis DN.Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas.Cancer Res. 1994 Oct 15;54(20):5262-4.
    7923151
  • Sgroi D, Stamenkovic I.The B-cell adhesion molecule CD22 is cross-species reactive and recognizes distinct sialoglycoproteins on different functional T-cell sub-populations.Scand J Immunol. 1994 May;39(5):433-8.
    8191218
  • Powell LD, Sgroi D, Sjoberg ER, Stamenkovic I, Varki A.Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition.J Biol Chem. 1993 Apr 5;268(10):7019-27.
    8463235
  • Aruffo A, Kanner SB, Sgroi D, Ledbetter JA, Stamenkovic I.CD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling.Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10242-6.
    1438211
  • Love JT, Padula SJ, Lingenheld EG, Amin JK, Sgroi DC, Wong RL, Sha'fi RI, Clark RB.Effects of H-7 are not exclusively mediated through protein kinase C or the cyclic nucleotide-dependent kinases.Biochem Biophys Res Commun. 1989 Jul 14;162(1):138-43.
    2546543
  • Padula SJ, Sgroi DC, Lingenheld EG, Love JT, Chou CH, Clark RB.T cell receptor beta chain gene rearrangement shared by murine T cell lines derived from a site of autoimmune inflammation.J Clin Invest. 1988 Jun;81(6):1810-8.
    2454949