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Suzanne George, MD

Publications

  • George S, Barysauskas C, Serrano C, Oduyebo T, Rauh-Hain JA, Del Carmen MG, Demetri GD, Muto MG.Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.Cancer. 2014 Jun 12.
    24923260
  • von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Casper ES, Conrad EU, DeLaney TF, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O'Donnell RJ, Pappo AS, Paz IB, Pfeifer JD, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Van Tine BA, Wayne JD, Bergman MA, Sundar H.Gastrointestinal stromal tumors, version 2.2014.J Natl Compr Canc Netw. 2014 Jun;12(6):853-62.
    24925196
  • Grothey A, George S, van Cutsem E, Blay JY, Sobrero A, Demetri GD.Optimizing Treatment Outcomes With Regorafenib: Personalized Dosing and Other Strategies to Support Patient Care.Oncologist. 2014 Jun;19(6):669-680.
    24821824
  • Serrano C, George S.Recent advances in the treatment of gastrointestinal stromal tumors.Ther Adv Med Oncol. 2014 May;6(3):115-127.
    24790651
  • Fiore M, Coppola S, Cannell AJ, Colombo C, Bertagnolli MM, George S, Le Cesne A, Gladdy RA, Casali PG, Swallow CJ, Gronchi A, Bonvalot S, Raut CP.Desmoid-Type Fibromatosis and Pregnancy: A Multi-institutional Analysis of Recurrence and Obstetric Risk.Ann Surg. 2014 May;259(5):973-8.
    24477160
  • von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Casper ES, Conrad EU, Delaney TF, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O'Donnell RJ, Pappo AS, Paz IB, Pfeifer JD, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Van Tine BA, Wayne JD, Bergman MA, Sundar H.Soft tissue sarcoma, version 2.2014.J Natl Compr Canc Netw. 2014 Apr 1;12(4):473-83.
    24717567
  • Serrano C, Nucci MR, Tirumani SH, Raut CP, George S.Hormone dependency in metastatic low-grade leiomyosarcoma following uterine smooth muscle tumour of uncertain malignant potential.BMJ Case Rep. 2014;2014.
    24675802
  • George S, Feng Y, Manola J, Nucci MR, Butrynski JE, Morgan JA, Ramaiya N, Quek R, Penson RT, Wagner AJ, Harmon D, Demetri GD, Krasner C.Phase 2 trial of aromatase inhibition with letrozole in patients with uterine leiomyosarcomas expressing estrogen and/or progesterone receptors.Cancer. 2014 Mar 1;120(5):738-43.
    24222211
  • Shinagare AB, Jagannathan JP, Kurra V, Urban T, Manola J, Choy E, Demetri GD, George S, Ramaiya NH.Comparison of performance of various tumour response criteria in assessment of regorafenib activity in advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib.Eur J Cancer. 2014 Mar;50(5):981-6.
    24388774
  • Koh WJ, Greer BE, Abu-Rustum NR, Apte SM, Campos SM, Chan J, Cho KR, Cohn D, Crispens MA, Dupont N, Eifel PJ, Fader AN, Fisher CM, Gaffney DK, George S, Han E, Huh WK, Lurain JR, Martin L, Mutch D, Remmenga SW, Reynolds RK, Small W, Teng N, Tillmanns T, Valea FA, McMillian N, Hughes M.Uterine neoplasms, version 1.2014.J Natl Compr Canc Netw. 2014 Feb;12(2):248-80.
    24586086
  • Oduyebo T, Rauh-Hain AJ, Meserve EE, Seidman MA, Hinchcliff E, George S, Quade B, Nucci MR, Del Carmen MG, Muto MG.The value of re-exploration in patients with inadvertently morcellated uterine sarcoma.Gynecol Oncol. 2014 Feb;132(2):360-5.
    24296345
  • Coccia PF, Pappo AS, Altman J, Bhatia S, Borinstein SC, Flynn J, Frazier AL, George S, Goldsby R, Hayashi R, Huang MS, Johnson RH, Beaupin LK, Link MP, Oeffinger KC, Orr KM, Reed D, Spraker HL, Thomas DA, von Mehren M, Wechsler DS, Whelan KF, Zebrack B, Shead DA, Sundar H.Adolescent and young adult oncology, version 2.2014.J Natl Compr Canc Netw. 2014 Jan;12(1):21-32; quiz 32.
    24453290
  • Wagner AJ, Chugh R, Rosen LS, Morgan JA, George S, Gordon M, Dunbar J, Normant E, Grayzel D, Demetri GD.A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas.Clin Cancer Res. 2013 Nov 1;19(21):6020-9.
    24045182
  • Serrano C, George S.Leiomyosarcoma.Hematol Oncol Clin North Am. 2013 Oct;27(5):957-74.
    24093170
  • Rauh-Hain JA, Oduyebo T, Diver EJ, Guseh SH, George S, Muto MG, del Carmen MG.Uterine leiomyosarcoma: an updated series.Int J Gynecol Cancer. 2013 Jul;23(6):1036-43.
    23714705
  • Hensley ML, Wathen JK, Maki RG, Araujo DM, Sutton G, Priebat DA, George S, Soslow RA, Baker LH.Adjuvant therapy for high-grade, uterus-limited leiomyosarcoma: Results of a phase 2 trial (SARC 005).Cancer. 2013 Apr 15;119(8):1555-61.
    23335221
  • Baldini EH, Lapidus MR, Wang Q, Manola J, Orgill DP, Pomahac B, Marcus KJ, Bertagnolli MM, Devlin PM, George S, Abraham J, Ferrone ML, Ready JE, Raut CP.Predictors for major wound complications following preoperative radiotherapy and surgery for soft-tissue sarcoma of the extremities and trunk: importance of tumor proximity to skin surface.Ann Surg Oncol. 2013 May;20(5):1494-9.
    23242820
  • Martins F, de Oliveira MA, Wang Q, Sonis S, Gallottini M, George S, Treister N.A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients.Oral Oncol. 2013 Apr;49(4):293-8.
    23312237
  • Iasonos A, Keung EZ, Zivanovic O, Mancari R, Peiretti M, Nucci M, George S, Colombo N, Carinelli S, Hensley ML, Raut CP.External validation of a prognostic nomogram for overall survival in women with uterine leiomyosarcoma.Cancer. 2013 Mar 1.
    23456762
  • Yap TA, Arkenau HT, Camidge DR, George S, Serkova NJ, Gwyther SJ, Spratlin JL, Lal R, Spicer J, Desouza NM, Leach MO, Chick J, Poondru S, Boinpally R, Gedrich R, Brock K, Stephens A, Eckhardt SG, Kaye SB, Demetri G, Scurr M.First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies.Clin Cancer Res. 2013 Feb 15;19(4):909-19.
    23403628
  • McBride SM, Raut CP, Lapidus M, Devlin PM, Marcus KJ, Bertagnolli M, George S, Baldini EH.Locoregional Recurrence After Preoperative Radiation Therapy for Retroperitoneal Sarcoma: Adverse Impact of Multifocal Disease and Potential Implications of Dose Escalation.Ann Surg Oncol. 2013 Feb 8.
    23392853
  • Ravegnini G, MariƱo-Enriquez A, Slater J, Eilers G, Wang Y, Zhu M, Nucci MR, George S, Angelini S, Raut CP, Fletcher JA.MED12 mutations in leiomyosarcoma and extrauterine leiomyoma.Mod Pathol. 2012 Dec 7.
    23222489
  • Morgan EA, Kozono DE, Wang Q, Mery CM, Butrynski JE, Baldini EH, George S, Nascimento AF, Raut CP.Cutaneous radiation-associated angiosarcoma of the breast: poor prognosis in a rare secondary malignancy.Ann Surg Oncol. 2012 Nov;19(12):3801-8.
    22890593
  • de Jesus-Gonzalez N, Robinson E, Penchev R, von Mehren M, Heinrich MC, Tap W, Wang Q, Demetri G, George S, Humphreys BD.Regorafenib induces rapid and reversible changes in plasma nitric oxide and endothelin-1.Am J Hypertens. 2012 Oct;25(10):1118-23.
    22785409
  • Coccia PF, Altman J, Bhatia S, Borinstein SC, Flynn J, George S, Goldsby R, Hayashi R, Huang MS, Johnson RH, Beaupin LK, Link MP, Oeffinger KC, Orr KM, Pappo AS, Reed D, Spraker HL, Thomas DA, von Mehren M, Wechsler DS, Whelan KF, Zebrack BJ, Sundar H, Shead DA.Adolescent and young adult oncology. Clinical practice guidelines in oncology.J Natl Compr Canc Netw. 2012 Sep;10(9):1112-50.
    22956810
  • Wagner AJ, Remillard SP, Zhang YX, Doyle LA, George S, Hornick JL.Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors.Mod Pathol. 2012 Sep 7.
    22955521
  • von Mehren M, Benjamin RS, Bui MM, Casper ES, Conrad EU, DeLaney TF, Ganjoo KN, George S, Gonzalez R, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O'Donnell RJ, Paz B, Pfeifer JD, Pollock RE, Randall RL, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Shankar S, Van Tine BA, Wayne J, Sundar H, McMillian NR.Soft tissue sarcoma, version 2.2012: featured updates to the NCCN guidelines.J Natl Compr Canc Netw. 2012 Aug;10(8):951-60.
    22878820
  • George S, Wang Q, Heinrich MC, Corless CL, Zhu M, Butrynski JE, Morgan JA, Wagner AJ, Choy E, Tap WD, Yap JT, Van den Abbeele AD, Manola JB, Solomon SM, Fletcher JA, von Mehren M, Demetri GD.Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial.J Clin Oncol. 2012 Jul 1;30(19):2401-7.
    22614970
  • Shah SH, Jagannathan JP, Krajewski K, O'Regan KN, George S, Ramaiya NH.Uterine sarcomas: then and now.AJR Am J Roentgenol. 2012 Jul;199(1):213-23. Review.
    22733915
  • Quek R, Wang Q, Morgan JA, Shapiro GI, Butrynski JE, Ramaiya N, Huftalen T, Jederlinic N, Manola J, Wagner AJ, Demetri GD, George S.Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.Clin Cancer Res. 2011 Feb 15;17(4):871-9.
    21177764
  • George S, Trent JC.The role of imatinib plasma level testing in gastrointestinal stromal tumor.Cancer Chemother Pharmacol. 2011 Jan;67 Suppl 1:S45-50. Review.
    21140148
  • Wang WL, Conley A, Reynoso D, Nolden L, Lazar AJ, George S, Trent JC.Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor.Cancer Chemother Pharmacol. 2011 Jan;67 Suppl 1:S15-24. Review.
    21181476
  • Haglund KE, Raut CP, Nascimento AF, Wang Q, George S, Baldini EH.Recurrence Patterns and Survival for Patients with Intermediate- and High-Grade Myxofibrosarcoma.Int J Radiat Oncol Biol Phys. 2010 Oct 15.
    20951504
  • Biermann JS, Adkins DR, Benjamin RS, Brigman B, Chow W, Conrad EU, Frassica DA, Frassica FJ, George S, Hande KR, Hornicek FJ, Letson GD, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, Somaiah N, Yasko AW.Bone cancer.J Natl Compr Canc Netw. 2010 Jun;8(6):688-712.
    20581300
  • Marrari A, Trent JC, George S.Personalized cancer therapy for gastrointestinal stromal tumor: synergizing tumor genotyping with imatinib plasma levels.Curr Opin Oncol. 2010 Jul;22(4):336-41. Review.
    20489620
  • Quek R, George S.Update on the treatment of gastrointestinal stromal tumors (GISTs): role of imatinib.Biologics. 2010;4:19-31.
    20161982
  • Raut CP, Wang Q, Manola J, Morgan JA, George S, Wagner AJ, Butrynski JE, Fletcher CD, Demetri GD, Bertagnolli MM.Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate.Ann Surg Oncol. 2010 Feb;17(2):407-15.
    19898902
  • Theman TA, Hartzell TL, Sinha I, Polson K, Morgan J, Demetri GD, Orgill DP, George S.Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage.J Clin Oncol. 2009 Nov 20;27(33):e198-200. Review.
    19805684
  • Raut CP, Nucci MR, Wang Q, Manola J, Bertagnolli MM, Demetri GD, Morgan JA, Muto MG, Fletcher CD, George S.Predictive value of FIGO and AJCC staging systems in patients with uterine leiomyosarcoma.Eur J Cancer. 2009 Nov;45(16):2818-24.
    19647426
  • Demetri GD, Heinrich MC, Fletcher JA, Fletcher CD, Van den Abbeele AD, Corless CL, Antonescu CR, George S, Morgan JA, Chen MH, Bello CL, Huang X, Cohen DP, Baum CM, Maki RG.Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure.Clin Cancer Res. 2009 Sep 15;15(18):5902-9.
    19737946
  • Mery CM, George S, Bertagnolli MM, Raut CP.Secondary sarcomas after radiotherapy for breast cancer: sustained risk and poor survival.Cancer. 2009 Sep 15;115(18):4055-63.
    19526590
  • George S,Merriam P,Maki RG,Van den Abbeele AD,Yap JT,Akhurst T,Harmon DC,Bhuchar G,O'Mara MM,D'Adamo DR,Morgan J,Schwartz GK,Wagner AJ,Butrynski JE,Demetri GD,Keohan ML.Multicenter Phase II Trial of Sunitinib in the Treatment of Nongastrointestinal Stromal Tumor Sarcomas.J Clin Oncol. 2009 Jul 1;27(19):3154-60.
    19451429
  • Quek R,Morgan JA,George S,Butrynski JE,Polson K,Meyer F,Demetri GD,Block SD.Small molecule tyrosine kinase inhibitor and depression.J Clin Oncol. 2009 Jan 10;27(2):312-3.
    19064960
  • Haining WN,Davies J,Kanzler H,Drury L,Brenn T,Evans J,Angelosanto J,Rivoli S,Russell K,George S,Sims P,Neuberg D,Li X,Kutok J,Morgan J,Wen P,Demetri G,Coffman RL,Nadler LM.CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans.Clin Cancer Res. 2008 Sep 1;14(17):5626-34.
    18765557
  • Bertagnolli MM,Morgan JA,Fletcher CD,Raut CP,Dileo P,Gill RR,Demetri GD,George S.Multimodality treatment of mesenteric desmoid tumours.Eur J Cancer. 2008 Nov;44(16):2404-10.
    18706807
  • Ghose T, Swendeman D, George S, Chowdhury D.Mobilizing collective identity to reduce HIV risk among sex workers in Sonagachi, India: The boundaries, consciousness, negotiation framework.Soc Sci Med. 2008 Jul;67(2):311-20.
    18455855
  • Suresh V, Shelley DA, Shin HW, George SC.Effect of Heterogeneous Ventilation and Nitric Oxide Production on Exhaled Nitric Oxide Profiles.J Appl Physiol. 2008 Jun;104(6):1743-52.
    18356478
  • Khanra S, Kuepper K, Weyhermuller T, Prinz M, Raekers M, Voget S, Postnikov AV, de Groot FM, George SJ, Coldea M, Neumann M, Chaudhuri P.Star-Shaped Molecule of Mn(II)4O6 Core with an St = 10 High-Spin State. A Theoretical and Experimental Study with XPS, XMCD, and Other Magnetic Methods.Inorg Chem. 2008 Jun 2;47(11):4605-17.
    18459725
  • George SM, Metris A, Stringer SC.Physiological state of single cells of Listeria innocua in organic acids.Int J Food Microbiol. 2008 May 31;124(2):204-10.
    18456356
  • George SE, Ramalakshmi K, Mohan Rao LJ.A perception on health benefits of coffee.Crit Rev Food Sci Nutr. 2008 May;48(5):464-86.
    18464035
  • George S, Kishen A.Influence of Photosensitizer Solvent on the Mechanisms of Photoactivated Killing of Enterococcus faecalis.Photochem Photobiol. 2008 May-Jun;84(3):734-40.
    18435622
  • George S, Kesavadas T.Low cost augmented reality for training of MRI-guided needle biopsy of the spine.Stud Health Technol Inform. 2008;132:138-40.
    18391274
  • George SJ, Igarashi RY, Xiao Y, Hernandez JA, Demuez M, Zhao D, Yoda Y, Ludden PW, Rubio LM, Cramer SP.Extended X-ray absorption fine structure and nuclear resonance vibrational spectroscopy reveal that NifB-co, a FeMo-co precursor, comprises a 6Fe core with an interstitial light atom.J Am Chem Soc. 2008 Apr 30;130(17):5673-80.
    18386899
  • George S, Dharmadhikari A.Writing a book review: frequently asked questions answered.Br J Hosp Med (Lond). 2008 Feb;69(2):M30-1. Review.
    18386737
  • Dworschak M, Audi G, Blaum K, Delahaye P, George S, Hager U, Herfurth F, Herlert A, Kellerbauer A, Kluge HJ, Lunney D, Schweikhard L, Yazidjian C.Restoration of the n=82 shell gap from direct mass measurements of 132,134Sn.Phys Rev Lett. 2008 Feb 22;100(7):072501.
    18352543
  • Patel TV, Morgan JA, Demetri GD, George S, Maki RG, Quigley M, Humphreys BD.A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib.Journal of the National Cancer Institute. 2008 Feb 20;100(4):282-4.
    18270341
  • Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, Schoen FJ, Van den Abbeele AD, Demetri GD, Force T, Chen MH.Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib.Lancet. 2007 Dec 15;370(9604):2011-9.
    18083403
  • Ito H, Hornick JL, Bertagnolli MM, George S, Morgan JA, Baldini EH, Wagner AJ, Demetri GD, Raut CP.Leiomyosarcoma of the inferior vena cava: survival after aggressive management.Ann Surg Oncol. 2007 Dec;14(12):3534-41.
    17896156
  • Desai J, Shankar S, Heinrich MC, Fletcher JA, Fletcher CD, Manola J, Morgan JA, Corless CL, George S, Tuncali K, Silverman SG, Van den Abbeele AD, van Sonnenberg E, Demetri GD.Clonal evolution of resistance to imatinib in patients with metastatic gastrointestinal stromal tumors.Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5398-405.
    17875769
  • George S.Sunitinib, a multitargeted tyrosine kinase inhibitor, in the management of gastrointestinal stromal tumor.Curr Oncol Rep. 2007 Jul;9(4):323-7. Review.
    17588358
  • Desai J, Yassa L, Marqusee E, George S, Frates MC, Chen MH, Morgan JA, Dychter SS, Larsen PR, Demetri GD, Alexander EK.Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors.Ann Intern Med. 2006 Nov 7;145(9):660-4.
    17088579
  • Raut CP, Posner M, Desai J, Morgan JA, George S, Zahrieh D, Fletcher CD, Demetri GD, Bertagnolli MM.Surgical Management of Advanced Gastrointestinal Stromal Tumors After Treatment With Targeted Systemic Therapy Using Kinase Inhibitors.J Clin Oncol. 2006 May 20;24(15):2325-2331.
    16710031
  • George S, Desai J, Paul Eder J, Manola J, Ryan DP, Appleman LJ, Demetri GD.Selective kinase inhibition with daily imatinib intensifies toxicity of chemotherapy in patients with solid tumours.Eur J Cancer. 2006 May;42(7):864-70.
    16503137