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Christophe Benoist, MD, PhD

Publications

  • Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer M, Nolan G, Kobayashi K, von Boehmer H, Mathis D, Benoist C, , Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S.The transcriptional landscape of αβ T cell differentiation.Nat Immunol. 2013 May 5.
    23644507
  • Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, , Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S.Identification of transcriptional regulators in the mouse immune system.Nat Immunol. 2013 Apr 28.
    23624555
  • Sitrin J, Ring A, Garcia KC, Benoist C, Mathis D.Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.J Exp Med. 2013 May 6.
    23650440
  • Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF.Regulatory T cells: recommendations to simplify the nomenclature.Nat Immunol. 2013 Apr;14(4):307-8.
    23507634
  • Shay T, Jojic V, Zuk O, Rothamel K, Puyraimond-Zemmour D, Feng T, Wakamatsu E, Benoist C, Koller D, Regev A, .Conservation and divergence in the transcriptional programs of the human and mouse immune systems.Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2946-51.
    23382184
  • Wakamatsu E, Mathis D, Benoist C.Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells.Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1023-8.
    23277554
  • Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, Helft J, Chow A, Elpek KG, Gordonov S, Mazloom AR, Ma'ayan A, Chua WJ, Hansen TH, Turley SJ, Merad M, Randolph GJ, , Gautier EL, Jakubzick C, Randolph GJ, Best AJ, Knell J, Goldrath A, Miller J, Brown B, Merad M, Jojic V, Koller D, Cohen N, Brennan P, Brenner M, Shay T, Regev A, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S, Jianu R, Laidlaw D, Collins J, Narayan K, Sylvia K, Kang J, Gazit R, Garrison BS, Rossi DJ, Kim F, Rao TN, Wagers A, Shinton SA, Hardy RR, Monach P, Bezman NA, Sun JC, Kim CC, Lanier LL, Heng T, Kreslavsky T, Painter M, Ericson J, Davis S, Mathis D, Benoist C.Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.Nat Immunol. 2012 Sep 30;13(11):1118-1128.
    23023392
  • Donner Y, Feng T, Benoist C, Koller D.Imputing gene expression from selectively reduced probe sets.Nat Methods. 2012 Nov;9(11):1120-5.
    23064520
  • Benoist C, Lanier L, Merad M, Mathis D, .Consortium biology in immunology: the perspective from the Immunological Genome Project.Nat Rev Immunol. 2012 Oct;12(10):734-40.
    22955842
  • Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C.A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.Nat Immunol. 2012 Oct;13(10):972-80.
    22961053
  • Benoist C, Mathis D.Treg cells, life history, and diversity.Cold Spring Harb Perspect Biol. 2012 Sep;4(9):a007021.
    22952391
  • Bandukwala HS, Wu Y, Feurer M, Chen Y, Barbosa B, Ghosh S, Stroud JC, Benoist C, Mathis D, Rao A, Chen L.Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.Immunity. 2011 Mar 30.
    21458306
  • Painter MW, Davis S, Hardy RR, Mathis D, Benoist C, .Transcriptomes of the B and T lineages compared by multiplatform microarray profiling.J Immunol. 2011 Mar 1;186(5):3047-57.
    21307297
  • Huang GJ, Smith AL, Gray DH, Cosgrove C, Singer BH, Edwards A, Sim S, Parent JM, Johnsen A, Mott R, Mathis D, Klenerman P, Benoist C, Flint J.A genetic and functional relationship between T cells and cellular proliferation in the adult hippocampus.PLoS Biol. 2010;8(12):e1000561.
    21179499
  • Rubtsov YP, Niec RE, Josefowicz S, Li L, Darce J, Mathis D, Benoist C, Rudensky AY.Stability of the regulatory T cell lineage in vivo.Science. 2010 Sep 24;329(5999):1667-71.
    20929851
  • Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, Farinelli L, Østerås M, Whitley A, Yuan W, Gan X, Goodson M, Klenerman P, Satpathy A, Mathis D, Benoist C, Adams DJ, Mott R, Flint J.Commercially available outbred mice for genome-wide association studies.PLoS Genet. 2010;6(9).
    20838427
  • Nishio J, Feuerer M, Wong J, Mathis D, Benoist C.Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.J Exp Med. 2010 Aug 30;207(9):1879-89.
    20679403
  • Koh AS, Kingston RE, Benoist C, Mathis D.Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13016-21.
    20615959
  • Feuerer M, Hill JA, Kretschmer K, von Boehmer H, Mathis D, Benoist C.Genomic definition of multiple ex vivo regulatory T cell subphenotypes.Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5919-24.
    20231436
  • Monach PA, Nigrovic PA, Chen M, Hock H, Lee DM, Benoist C, Mathis D.Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1.Arthritis Rheum. 2010 Mar;62(3):753-64.
    20191628
  • Abramson J, Giraud M, Benoist C, Mathis D.Aire's partners in the molecular control of immunological tolerance.Cell. 2010 Jan 8;140(1):123-35.
    20085707
  • Mathis D, Benoist C.Levees of immunological tolerance.Nat Immunol. 2010 Jan;11(1):3-6.
    20016503
  • Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U.Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.Arthritis Rheum. 2009 Aug;60(8):2314-24.
    19644878
  • Feuerer M, Hill JA, Mathis D, Benoist C.Foxp3+ regulatory T cells: differentiation, specification, subphenotypes.Nat Immunol. 2009 Jul;10(7):689-95. Review.
    19536194
  • D'Alise AM,Auyeung V,Feuerer M,Nishio J,Fontenot J,Benoist C,Mathis D.The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors.Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19857-62.
    19073938
  • Hill JA,Hall JA,Sun CM,Cai Q,Ghyselinck N,Chambon P,Belkaid Y,Mathis D,Benoist C.Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.Immunity. 2008 Nov;29(5):758-70.
    19006694
  • Nigrovic PA,Gray DH,Jones T,Hallgren J,Kuo FC,Chaletzky B,Gurish M,Mathis D,Benoist C,Lee DM.Genetic inversion in mast cell-deficient (W(sh)) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.Am J Pathol. 2008 Dec;173(6):1693-701.
    18988802
  • Koh AS,Kuo AJ,Park SY,Cheung P,Abramson J,Bua D,Carney D,Shoelson SE,Gozani O,Kingston RE,Benoist C,Mathis D.Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15878-83.
    18840680
  • Venanzi ES,Melamed R,Mathis D,Benoist C.The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription.Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15860-5.
    18838677
  • Villasenor J,Besse W,Benoist C,Mathis D.Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated.Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15854-9.
    18836079
  • Guerau-de-Arellano M,Mathis D,Benoist C.Transcriptional impact of Aire varies with cell type.Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14011-6.
    18780794
  • Gavanescu I,Benoist C,Mathis D.B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients.Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13009-14.
    18755889
  • Haxhinasto S, Mathis D, Benoist C.The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.J Exp Med. 2008 Mar 17;205(3):565-74.
    18283119
  • Hill JA, Feuerer M, Tash K, Haxhinasto S, Perez J, Melamed R, Mathis D, Benoist C.Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.Immunity. 2007 Nov;27(5):786-800.
    18024188
  • Feuerer M, Jiang W, Holler PD, Satpathy A, Campbell C, Bogue M, Mathis D, Benoist C.Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes.Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18181-6.
    17991775
  • Gray D, Abramson J, Benoist C, Mathis D.Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire.J Exp Med. 2007 Oct 29;204(11):2521-8.
    17908938
  • Obst R, van Santen HM, Melamed R, Kamphorst AO, Benoist C, Mathis D.Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation.Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15460-5.
    17881563
  • Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C.Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4+ T Cells.J Immunol. 2007 Jun 1;178(11):7032-7041.
    17513752
  • Holler PD, Yamagata T, Jiang W, Feuerer M, Benoist C, Mathis D.The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice.Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7187-92.
    17438291
  • Gavanescu I, Kessler B, Ploegh H, Benoist C, Mathis D.Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4583-7.
    17360567
  • Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY.Lack of Foxp3 function and expression in the thymic epithelium.J Exp Med. 2007 Mar 19;204(3):475-80.
    17353370
  • Haxhinasto S, Benoist C, Mathis D.Regulatory T-cell differentiation: Committed to control: a precocious choice?.Immunol Cell Biol. 2007 Apr;85(3):175-6.
    17310224
  • Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A.FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.Cell. 2006 Jul 28;126(2):375-87.
    16873067
  • Hyatt G, Melamed R, Park R, Seguritan R, Laplace C, Poirot L, Zucchelli S, Obst R, Matos M, Venanzi E, Goldrath A, Nguyen L, Luckey J, Yamagata T, Herman A, Jacobs J, Mathis D, Benoist C.Gene expression microarrays: glimpses of the immunological genome.Nat Immunol. 2006 Jul;7(7):686-91.
    16785882
  • Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D.Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution.Science. 2006 Mar 24;311(5768):1775-8.
    16556845
  • Huang H, Kearney JF, Grusby MJ, Benoist C, Mathis D.Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3734-9.
    16505356
  • Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D.Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3304-9.
    16492737
  • Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C.Particularities of the vasculature can promote the organ specificity of autoimmune attack.Nat Immunol. 2006 Mar;7(3):284-92.
    16444258
  • Turley SJ, Lee JW, Dutton-Swain N, Mathis D, Benoist C.Endocrine self and gut non-self intersect in the pancreatic lymph nodes.Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17729-33.
    16317068
  • Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C.Modifier loci condition autoimmunity provoked by Aire deficiency.J Exp Med. 2005 Sep 19;202(6):805-15.
    16172259
  • Villaseor J, Benoist C, Mathis D.AIRE and APECED: molecular insights into an autoimmune disease.Immunol Rev. 2005 Apr;204:156-64.
    15790357
  • Feuerer M, Benoist C, Mathis D.Green T(R) cells.Immunity. 2005 Mar;22(3):271-2.
    15780983
  • Zucchelli S, Holler P, Yamagata T, Roy M, Benoist C, Mathis D.Defective central tolerance induction in NOD mice: genomics and genetics.Immunity. 2005 Mar;22(3):385-96.
    15780994
  • Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C.Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis.Arthritis Rheum. 2004 Aug;50(8):2685-94.
    15334485
  • Herman AE, Freeman GJ, Mathis D, Benoist C.CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion.J Exp Med. 2004 Jun 7;199(11):1479-89.
    15184501
  • Martin-Orozco N, Chen Z, Poirot L, Hyatt E, Chen A, Kanagawa O, Sharpe A, Mathis D, Benoist C.Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand.J Immunol. 2003 Dec 15;171(12):6954-60.
    14662903
  • Turley S, Poirot L, Hattori M, Benoist C, Mathis D.Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model.J Exp Med. 2003 Nov 17;198(10):1527-37.
    14623908
  • Matsumoto I, Lee DM, Goldbach-Mansky R, Sumida T, Hitchon CA, Schur PH, Anderson RJ, Coblyn JS, Weinblatt ME, Brenner M, Duclos B, Pasquali JL, El-Gabalawy H, Mathis D, Benoist C.Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders.Arthritis Rheum. 2003 Apr;48(4):944-54.
    12687536
  • Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D.Projection of an immunological self shadow within the thymus by the aire protein.Science. 2002 Nov 15;298(5597):1395-401.
    12376594
  • Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB.Mast cells: a cellular link between autoantibodies and inflammatory arthritis.Science. 2002 Sep 6;297(5587):1689-92.
    12215644
  • Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, Gravallese E, Mathis D, Benoist C.Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis.J Exp Med. 2002 Jul 1;196(1):77-85.
    12093872
  • Goldrath AW, Sivakumar PV, Glaccum M, Kennedy MK, Bevan MJ, Benoist C, Mathis D, Butz EA.Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells.J Exp Med. 2002 Jun 17;195(12):1515-22.
    12070279
  • Maccioni M, Zeder-Lutz G, Huang H, Ebel C, Gerber P, Hergueux J, Marchal P, Duchatelle V, Degott C, van Regenmortel M, Benoist C, Mathis D.Arthritogenic monoclonal antibodies from K/BxN mice.J Exp Med. 2002 Apr 15;195(8):1071-7.
    11956298
  • Matsumoto I, Maccioni M, Lee DM, Maurice M, Simmons B, Brenner M, Mathis D, Benoist C.How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease.Nat Immunol. 2002 Apr;3(4):360-5.
    11896391
  • Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D.Arthritis critically dependent on innate immune system players.Immunity. 2002 Feb;16(2):157-68.
    11869678
  • Mathis D, Vence L, Benoist C.beta-Cell death during progression to diabetes.Nature. 2001 Dec 13;414(6865):792-8.
    11742411
  • Gonzalez A, Andre-Schmutz I, Carnaud C, Mathis D, Benoist C.Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes.Nat Immunol. 2001 Dec;2(12):1117-25.
    11713466
  • Witherden D, van Oers N, Waltzinger C, Weiss A, Benoist C, Mathis D.Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules.J Exp Med. 2000 Jan 17;191(2):355-64.
    10637279
  • Matsumoto I, Staub A, Benoist C, Mathis D.Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme.Science. 1999 Nov 26;286(5445):1732-5.
    10576739
  • Lhder F, Hglund P, Allison JP, Benoist C, Mathis D.Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes.J Exp Med. 1998 Feb 2;187(3):427-32.
    9449722
  • Gonzalez A, Katz JD, Mattei MG, Kikutani H, Benoist C, Mathis D.Genetic control of diabetes progression.Immunity. 1997 Dec;7(6):873-83.
    9430232
  • Tourne S, Miyazaki T, Oxenius A, Klein L, Fehr T, Kyewski B, Benoist C, Mathis D.Selection of a broad repertoire of CD4+ T cells in H-2Ma0/0 mice.Immunity. 1997 Aug;7(2):187-95.
    9285404
  • Rooke R, Waltzinger C, Benoist C, Mathis D.Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses.Immunity. 1997 Jul;7(1):123-34.
    9252125
  • Nakano N, Rooke R, Benoist C, Mathis D.Positive selection of T cells induced by viral delivery of neopeptides to the thymus.Science. 1997 Jan 31;275(5300):678-83.
    9005856
  • Kouskoff V, Korganow AS, Duchatelle V, Degott C, Benoist C, Mathis D.Organ-specific disease provoked by systemic autoimmunity.Cell. 1996 Nov 29;87(5):811-22.
    8945509
  • Miyazaki T, Dierich A, Benoist C, Mathis D.Independent modes of natural killing distinguished in mice lacking Lag3.Science. 1996 Apr 19;272(5260):405-8.
    8602528
  • Miyazaki T, Wolf P, Tourne S, Waltzinger C, Dierich A, Barois N, Ploegh H, Benoist C, Mathis D.Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway.Cell. 1996 Feb 23;84(4):531-41.
    8598040
  • Katz JD, Benoist C, Mathis D.T helper cell subsets in insulin-dependent diabetes.Science. 1995 May 26;268(5214):1185-8.
    7761837
  • Katz JD, Wang B, Haskins K, Benoist C, Mathis D.Following a diabetogenic T cell from genesis through pathogenesis.Cell. 1993 Sep 24;74(6):1089-100.
    8402882
  • Gilfillan S, Dierich A, Lemeur M, Benoist C, Mathis D.Mice lacking TdT: mature animals with an immature lymphocyte repertoire.Science. 1993 Aug 27;261(5125):1175-8.
    8356452
  • Chan SH, Cosgrove D, Waltzinger C, Benoist C, Mathis D.Another view of the selective model of thymocyte selection.Cell. 1993 Apr 23;73(2):225-36.
    8097430
  • Viville S, Neefjes J, Lotteau V, Dierich A, Lemeur M, Ploegh H, Benoist C, Mathis D.Mice lacking the MHC class II-associated invariant chain.Cell. 1993 Feb 26;72(4):635-48.
    7679955
  • Cosgrove D, Gray D, Dierich A, Kaufman J, Lemeur M, Benoist C, Mathis D.Mice lacking MHC class II molecules.Cell. 1991 Sep 6;66(5):1051-66.
    1909605
  • Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D.Superantigens interact with MHC class II molecules outside of the antigen groove.Cell. 1990 Sep 21;62(6):1115-21.
    2401011
  • Bhme J, Schuhbaur B, Kanagawa O, Benoist C, Mathis D.MHC-linked protection from diabetes dissociated from clonal deletion of T cells.Science. 1990 Jul 20;249(4966):293-5.
    2115690
  • Berg LJ, Pullen AM, Fazekas de St Groth B, Mathis D, Benoist C, Davis MM.Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.Cell. 1989 Sep 22;58(6):1035-46.
    2476238
  • Benoist C, Mathis D.Positive selection of the T cell repertoire: where and when does it occur?.Cell. 1989 Sep 22;58(6):1027-33.
    2505933
  • Bhme J, Haskins K, Stecha P, van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D.Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant.Science. 1989 Jun 9;244(4909):1179-83.
    2499048
  • van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D.Compartmentalization of MHC class II gene expression in transgenic mice.Cell. 1988 May 6;53(3):357-70.
    3259162
  • Dorn A, Bollekens J, Staub A, Benoist C, Mathis D.A multiplicity of CCAAT box-binding proteins.Cell. 1987 Sep 11;50(6):863-72.
    3476205
  • Landais D, Waltzinger C, Beck BN, Staub A, McKean DJ, Benoist C, Mathis D.Functional sites on Ia molecules: a molecular dissection of A alpha immunogenicity.Cell. 1986 Oct 24;47(2):173-81.
    2429774
  • Le Meur M, Gerlinger P, Benoist C, Mathis D.Correcting an immune-response deficiency by creating E alpha gene transgenic mice.Nature. 1985 Jul 4-10;316(6023):38-42.
    3925351
  • Benoist CO, Mathis DJ, Kanter MR, Williams VE, McDevitt HO.Regions of allelic hypervariability in the murine A alpha immune response gene.Cell. 1983 Aug;34(1):169-77.
    6309407
  • Mathis DJ, Benoist CO, Williams VE, Kanter MR, McDevitt HO.The murine E alpha immune response gene.Cell. 1983 Mar;32(3):745-54.
    6403249