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Jonathan S. Duke-Cohan, Ph.D.

Publications

  • Naito M, Hainz U, Burkhardt UE, Fu B, Ahove D, Stevenson KE, Rajasagi M, Zhu B, Alonso A, Witten E, Matsuoka KI, Neuberg D, Duke-Cohan JS, Wu CJ, Freeman GJ.CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells.Cancer Immunol Immunother. 2012 Aug 25.
    22926059
  • Marina O, Duke-Cohan JS, Wu CJ.A coprecipitation-based validation methodology for interactions identified using protein microarrays.Methods Mol Biol. 2011;723:239-54.
    21370070
  • Marina O, Hainz U, Biernacki MA, Zhang W, Cai A, Duke-Cohan JS, Liu F, Brusic V, Neuberg D, Kutok JL, Alyea EP, Canning CM, Soiffer RJ, Ritz J, Wu CJ.Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens.Cancer Res. 2010 Feb 15;70(4):1344-55.
    20124481
  • Krishnaswamy S, Kanteti R, Duke-Cohan JS, Loganathan S, Liu W, Ma PC, Sattler M, Singleton PA, Ramnath N, Innocenti F, Nicolae DL, Ouyang Z, Liang J, Minna J, Kozloff MF, Ferguson MK, Natarajan V, Wang YC, Garcia JG, Vokes EE, Salgia R.Ethnic differences and functional analysis of MET mutations in lung cancer.Clin Cancer Res. 2009 Sep 15;15(18):5714-23.
    19723643
  • Rabinovsky R, Pochanard P, McNear C, Brachmann SM, Duke-Cohan JS, Garraway LA, Sellers WR.p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.Mol Cell Biol. 2009 Oct;29(19):5377-88.
    19635806
  • Grandpre LE,Duke-Cohan JS,Ewald BA,Devoy C,Barouch DH,Letvin NL,Reinherz EL,Baden LR,Dolin R,Seaman MS.Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys.Vaccine. 2009 Mar 4;27(10):1549-56.
    19168105
  • Duke-Cohan JS,Wollenick K,Witten EA,Seaman MS,Baden LR,Dolin R,Reinherz EL.The heterogeneity of human antibody responses to vaccinia virus revealed through use of focused protein arrays.Vaccine. 2009 Feb 18;27(8):1154-65.
    19146908
  • Choi YI,Duke-Cohan JS,Ahmed WB,Handley MA,Mann F,Epstein JA,Clayton LK,Reinherz EL.PlexinD1 glycoprotein controls migration of positively selected thymocytes into the medulla.Immunity. 2008 Dec;29(6):888-98.
    19027330
  • Romero V, Larsen CE, Duke-Cohan JS, Fox EA, Romero T, Clavijo OP, Fici DA, Husain Z, Almeciga I, Alford DR, Awdeh ZL, Zuñiga J, El-Dahdah L, Alper CA, Yunis EJ.Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E.BMC Genet. 2007;8:14.
    17430593
  • Azouz A, Gunn TM, Duke-Cohan JS.Juvenile-onset loss of lipid-raft domains in attractin-deficient mice.Exp Cell Res. 2007 Feb 15;313(4):761-71.
    17196964
  • Khwaja FW, Duke-Cohan JS, Brat DJ, Van Meir EG.Attractin is elevated in the cerebrospinal fluid of patients with malignant astrocytoma and mediates glioma cell migration.Clin Cancer Res. 2006 Nov 1;12(21):6331-6.
    17085642
  • Gudi R, Barkinge J, Hawkins S, Chu F, Manicassamy S, Sun Z, Duke-Cohan JS, Prasad KV.Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD).Oncogene. 2006 Jun 8;25(24):3458-62.
    16491128
  • Duke-Cohan JS, Kang H, Liu H, Rudd CE.Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein.J Biol Chem. 2006 May 12;281(19):13743-50.
    16461356
  • Sedo A, Duke-Cohan JS, Balaziova E, Sedova LR.Dipeptidyl peptidase IV activity and/or structure homologs: contributing factors in the pathogenesis of rheumatoid arthritis?.Arthritis Res Ther. 2005;7(6):253-69.
    16277701
  • Di Giovanni S, Faden AI, Yakovlev A, Duke-Cohan JS, Finn T, Thouin M, Knoblach S, De Biase A, Bregman BS, Hoffman EP.Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth.FASEB J. 2005 Jan;19(1):153-4.
    15522907
  • Duke-Cohan JS, Kim JH, Azouz A.Attractin: cautionary tales for therapeutic intervention in molecules with pleiotropic functionality.J Environ Pathol Toxicol Oncol. 2004;23(1):1-11.
    14994991
  • Tang W, Duke-Cohan JS.Human secreted attractin disrupts neurite formation in differentiating cortical neural cells in vitro.J Neuropathol Exp Neurol. 2002 Sep;61(9):767-77.
    12230323
  • Pozzi N, Gaetaniello L, Martire B, De Mattia D, Balestrieri B, Cosentini E, Schlossman SF, Duke-Cohan JS, Pignata C.Defective surface expression of attractin on T cells in patients with common variable immunodeficiency (CVID).Clin Exp Immunol. 2001 Jan;123(1):99-104.
    11168005
  • He L, Gunn TM, Bouley DM, Lu XY, Watson SJ, Schlossman SF, Duke-Cohan JS, Barsh GS.A biochemical function for attractin in agouti-induced pigmentation and obesity.Nat Genet. 2001 Jan;27(1):40-7.
    11137996
  • McAdam AJ, Chang TT, Lumelsky AE, Greenfield EA, Boussiotis VA, Duke-Cohan JS, Chernova T, Malenkovich N, Jabs C, Kuchroo VK, Ling V, Collins M, Sharpe AH, Freeman GJ.Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.J Immunol. 2000 Nov 1;165(9):5035-40.
    11046032
  • Barsh G, Gunn T, He L, Schlossman S, Duke-Cohan J.Biochemical and genetic studies of pigment-type switching.Pigment Cell Res. 2000;13 Suppl 8:48-53.
    11041357
  • Kang H, Freund C, Duke-Cohan JS, Musacchio A, Wagner G, Rudd CE.SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55.EMBO J. 2000 Jun 15;19(12):2889-99.
    10856234
  • Duke-Cohan JS, Tang W, Schlossman SF.Attractin: a cub-family protease involved in T cell-monocyte/macrophage interactions.Adv Exp Med Biol. 2000;477:173-85.
    10849745
  • Tang W, Gunn TM, McLaughlin DF, Barsh GS, Schlossman SF, Duke-Cohan JS.Secreted and membrane attractin result from alternative splicing of the human ATRN gene.Proc Natl Acad Sci U S A. 2000 May 23;97(11):6025-30.
    10811918
  • Gunn TM, Miller KA, He L, Hyman RW, Davis RW, Azarani A, Schlossman SF, Duke-Cohan JS, Barsh GS.The mouse mahogany locus encodes a transmembrane form of human attractin.Nature. 1999 Mar 11;398(6723):152-6.
    10086356
  • Duke-Cohan JS, Gu J, McLaughlin DF, Xu Y, Freeman GJ, Schlossman SF.Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions.Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11336-41.
    9736737
  • Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF.Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells.J Immunol. 1996 Mar 1;156(5):1714-21.
    8596018
  • Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF.A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26).J Biol Chem. 1995 Jun 9;270(23):14107-14.
    7539799
  • Morimoto C, Lord CI, Zhang C, Duke-Cohan JS, Letvin NL, Schlossman SF.Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis.Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9960-4.
    7937926
  • Tanaka T, Duke-Cohan JS, Kameoka J, Yaron A, Lee I, Schlossman SF, Morimoto C.Enhancement of antigen-induced T-cell proliferation by soluble CD26/dipeptidyl peptidase IV.Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3082-6.
    7909158
  • Prasad KV, Kapeller R, Janssen O, Repke H, Duke-Cohan JS, Cantley LC, Rudd CE.Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.Mol Cell Biol. 1993 Dec;13(12):7708-17.
    8246987
  • Duke-Cohan JS, Morimoto C, Schlossman SF.Depletion of the helper/inducer (memory) T cell subset using a bispecific antibody-toxin conjugate directed against CD4 and CD29.Transplantation. 1993 Nov;56(5):1188-96.
    7504344
  • Prasad KV, Kapeller R, Janssen O, Duke-Cohan JS, Repke H, Cantley LC, Rudd CE.Regulation of CD4-p56lck-associated phosphatidylinositol 3-kinase (PI 3-kinase) and phosphatidylinositol 4-kinase (PI 4-kinase).Philos Trans R Soc Lond B Biol Sci. 1993 Oct 29;342(1299):35-42.
    7904344
  • Duke-Cohan JS, Morimoto C, Schlossman SF.Targeting of an activated T-cell subset using a bispecific antibody-toxin conjugate directed against CD4 and CD26.Blood. 1993 Oct 1;82(7):2224-34.
    8104537
  • Duke-Cohan JS, Rubinow A, Hirt R, Naor D.The reaction against autologous lymphoblasts as an indicator of lymphocyte hyperreactivity in rheumatoid arthritis.Clin Immunol Immunopathol. 1990 Feb;54(2):298-308.
    1967232
  • Duke-Cohan JS, Hirt R, Rottem M, Ben-Zvi A, Rubinow A, Naor D.Use of an autologous reaction in vitro to assess contributions of T and B lymphocytes to immune hyperreactivity of atopics.Clin Exp Allergy. 1989 Mar;19(2):163-8.
    2787692
  • Duke-Cohan JS.Observations on the contributions of environmental restraints and innate stem cell ability to hematopoietic regeneration.Int J Cell Cloning. 1988 Mar;6(2):116-24.
    3373033
  • Duke-Cohan JS, Hirt R, Dahan A, Naor D.On the immune reaction to autologous human lymphoblasts: evidence for the stimulation by activating factors rather than induction by autoantigens.Clin Immunol Immunopathol. 1987 May;43(2):229-42.
    2952382
  • Duke-Cohan JS, Davies AJ.Observations on the seeding of hematopoietic stem cells. Selective development in the transplanted recipient.Transplantation. 1987 Apr;43(4):600-2.
    2883746
  • Duke-Cohan JS.The multifactorial nature of osteoporosis: the potential of corticosteroid-binding globulin as a unifying regulator.Med Hypotheses. 1986 Dec;21(4):431-9.
    3642211
  • Naor D, Duke-Cohan JS.Suppressor cells and malignancy. I. Suppressor macrophages and suppressor T cells in experimental animals.Adv Immun Cancer Ther. 1986;2:1-129.
    2962474
  • Sharon R, Duke-Cohan JS, Galili U.Determination of ABO blood group zygosity by an antiglobulin rosetting technique and cell-based enzyme immunoassay.Vox Sang. 1986;50(4):245-9.
    3487882
  • Duke-Cohan JS, Weinberg H, Sharon R, Naor D.Immunological function in osteoporosis.Clin Immunol Immunopathol. 1985 Apr;35(1):125-9.
    3158457
  • Duke-Cohan JS, Davies AJ, Wallis VJ.Heterogeneity within the hematopoietic stem cell compartment: evidence for a marrow-seeding stem cell distinct from CFU-s.Int J Cell Cloning. 1985 Jan;3(1):44-56.
    2857754