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Andre Bernards, PhD


  • Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H.CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.Am J Med Genet A. 2014 Mar;164A(3):563-78.
  • Walker JA, Gouzi JY, Long JB, Huang S, Maher RC, Xia H, Khalil K, Ray A, Van Vactor D, Bernards R, Bernards A.Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.PLoS Genet. 2013 Nov;9(11):e1003958.
  • Blackburn JS, Liu S, Raiser DM, Martinez SA, Feng H, Meeker ND, Gentry J, Neuberg D, Look AT, Ramaswamy S, Bernards A, Trede NS, Langenau DM.Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.Leukemia. 2012 Sep;26(9):2069-78.
  • Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, Ramesh V, Reilly KM, Risner JW, Schorry EK, Upadhyaya M, Viskochil DH, Zhu Y, Hunter-Schaedle K, Giancotti FG.Back to the future: proceedings from the 2010 NF Conference.Am J Med Genet A. 2011 Feb;155(2):307-21.
  • Bernards A,Settleman J.Loss of the Ras regulator RASAL1: another route to Ras activation in colorectal cancer.Gastroenterology. 2009 Jan;136(1):46-8.
  • Bernards A, Settleman J.GEFs in growth factor signaling.Growth Factors. 2007 Oct;25(5):355-61. Review.
  • Kalpoe JS, Templeton KE, Horrevorts AM, Endtz HP, Kuijper EJ, Bernards AT, Klaassen CH.Molecular typing of a suspected cluster of Nocardia farcinica infections by use of randomly amplified polymorphic DNA, pulsed-field gel electrophoresis, and amplified fragment length polymorphism analyses.J Clin Microbiol. 2007 Dec;45(12):4048-50.
  • Balenci L, Saoudi Y, Grunwald D, Deloulme JC, Bouron A, Bernards A, Baudier J.IQGAP1 regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro.J Neurosci. 2007 Apr 25;27(17):4716-24.
  • Walker JA, Bernards A.Drosophila melanogaster neurofibromatosis-1: ROS, not Ras?.Nat Genet. 2007 Apr;39(4):443-5.
  • Walker JA, Tchoudakova AV, McKenney PT, Brill S, Wu D, Cowley GS, Hariharan IK, Bernards A.Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons.Genes Dev. 2006 Dec 1;20(23):3311-23.
  • Bernards A.Ras superfamily and interacting proteins database.Methods Enzymol. 2005;407:1-9.
  • Bernards A, Settleman J.GAPs in growth factor signalling.Growth Factors. 2005 Jun;23(2):143-9.
  • Bernards A, Settleman J.GAP control: regulating the regulators of small GTPases.Trends Cell Biol. 2004 Jul;14(7):377-85.
  • Bernards A.GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila.Biochim Biophys Acta. 2003 Mar 17;1603(2):47-82.
  • Kim TJ, Cariappa A, Iacomini J, Tang M, Shih S, Bernards A, Jacks T, Pillai S.Defective proliferative responses in B lymphocytes and thymocytes that lack neurofibromin.Mol Immunol. 2002 Feb;38(9):701-8.
  • Tong J, Hannan F, Zhu Y, Bernards A, Zhong Y.Neurofibromin regulates G protein-stimulated adenylyl cyclase activity.Nat Neurosci. 2002 Feb;5(2):95-6.
  • Williams JA, Su HS, Bernards A, Field J, Sehgal A.A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.Science. 2001 Sep 21;293(5538):2251-6.
  • Bernards A, Hariharan IK.Of flies and men--studying human disease in Drosophila.Curr Opin Genet Dev. 2001 Jun;11(3):274-8.
  • Guo HF, The I, Hannan F, Bernards A, Zhong Y.Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides.Science. 1997 May 2;276(5313):795-8.
  • The I, Hannigan GE, Cowley GS, Reginald S, Zhong Y, Gusella JF, Hariharan IK, Bernards A.Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.Science. 1997 May 2;276(5313):791-4.
  • Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ.The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.Mol Cell Biol. 1996 Sep;16(9):4869-78.
  • Jacks T, Shih TS, Schmitt EM, Bronson RT, Bernards A, Weinberg RA.Tumour predisposition in mice heterozygous for a targeted mutation in Nf1.Nat Genet. 1994 Jul;7(3):353-61.
  • The I, Murthy AE, Hannigan GE, Jacoby LB, Menon AG, Gusella JF, Bernards A.Neurofibromatosis type 1 gene mutations in neuroblastoma.Nat Genet. 1993 Jan;3(1):62-6.