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David M. Weinstock, MD


  • Wachter F, Grunert M, Blaj C, Weinstock DM, Jeremias I, Ehrhardt H.Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling.Cell Commun. Signal. 2013 Apr 17;11(1):27.
  • Wray J, Williamson EA, Singh SB, Wu Y, Cogle CR, Weinstock DM, Zhang Y, Lee SH, Zhou D, Shao L, Hauer-Jensen M, Pathak R, Klimek V, Nickoloff JA, Hromas R.PARP1 is required for chromosomal translocations.Blood. 2013 Apr 8.
  • Shindoh N, Yoda A, Yoda Y, Sullivan TJ, Weigert O, Lane AA, Kopp N, Bird L, Rodig SJ, Fox EA, Weinstock DM.Next-generation cDNA screening for oncogene and resistance phenotypes.PLoS ONE. 2012;7(11):e49201.
  • Ott CJ, Kopp N, Bird L, Paranal RM, Qi J, Bowman T, Rodig SJ, Kung AL, Bradner JE, Weinstock DM.BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia.Blood. 2012 Oct 4;120(14):2843-52.
  • van Bodegom D, Zhong J, Kopp N, Dutta C, Kim MS, Bird L, Weigert O, Tyner J, Pandey A, Yoda A, Weinstock DM.Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2.Blood. 2012 Oct 4;120(14):2853-63.
  • Weigert O, Weinstock DM.The evolving contribution of hematopoietic progenitor cells to lymphomagenesis.Blood. 2012 Sep 27;120(13):2553-61.
  • Dutta C, Day T, Kopp N, van Bodegom D, Davids MS, Ryan J, Bird L, Kommajosyula N, Weigert O, Yoda A, Fung H, Brown JR, Shapiro GI, Letai A, Weinstock DM.BCL2 suppresses PARP1 function and nonapoptotic cell death.Cancer Res. 2012 Aug 15;72(16):4193-203.
  • Weigert O, Lane AA, Bird L, Kopp N, Chapuy B, van Bodegom D, Toms AV, Marubayashi S, Christie AL, McKeown M, Paranal RM, Bradner JE, Yoda A, Gaul C, Vangrevelinghe E, Romanet V, Murakami M, Tiedt R, Ebel N, Evrot E, De Pover A, Régnier CH, Erdmann D, Hofmann F, Eck MJ, Sallan SE, Levine RL, Kung AL, Baffert F, Radimerski T, Weinstock DM.Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition.J Exp Med. 2012 Jan 23.
  • Weigert O, Kopp N, Lane AA, et al.Molecular ontogeny of donor-derived follicular lymphoma.Cancer Discovery. 2012 Jan 29;2(1):47-53.
  • Fung H, Weinstock DM.Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells.PLoS ONE. 2011;6(5):e20514.
  • DiCarlo AL, Maher C, Hick JL, Hanfling D, Dainiak N, Chao N, Bader JL, Coleman CN, Weinstock DM.Radiation injury after a nuclear detonation: medical consequences and the need for scarce resources allocation.Disaster Med Public Health Prep. 2011 Mar;5 Suppl 1:S32-44. Review.
  • Moskwa P, Buffa FM, Pan Y, Panchakshari R, Gottipati P, Muschel RJ, Beech J, Kulshrestha R, Abdelmohsen K, Weinstock DM, Gorospe M, Harris AL, Helleday T, Chowdhury D.miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.Mol Cell. 2011 Jan 21;41(2):210-20.
  • Weinstock DM.Epstein-Barr virus, lymphoma risk and the potential role of HIV infection in IBD patients undergoing immunosuppression.Dig Dis. 2010;28(3):519-24.
  • Xu Y, Sun Y, Jiang X, Ayrapetov MK, Moskwa P, Yang S, Weinstock DM, Price BD.The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair.J Cell Biol. 2010 Oct 4;191(1):31-43.
  • Tsai AG, Yoda A, Weinstock DM, Lieber MR.t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not.Blood. 2010 Sep 16;116(11):1993-4.
  • Wray J, Williamson EA, Chester S, Farrington J, Sterk R, Weinstock DM, Jasin M, Lee SH, Nickoloff JA, Hromas R.The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations.Cancer Genet Cytogenet. 2010 Jul 15;200(2):184-90.
  • Davids MS, Case C, Confer DL, Weisdorf DJ, Weinstock DM.Medical management of radiation victims in the United States.Health Phys. 2010 Jun;98(6):833-7.
  • Yoda A, Yoda Y, Chiaretti S, Bar-Natan M, Mani K, Rodig SJ, West N, Xiao Y, Brown JR, Mitsiades C, Sattler M, Kutok JL, DeAngelo DJ, Wadleigh M, Piciocchi A, Dal Cin P, Bradner JE, Griffin JD, Anderson KC, Stone RM, Ritz J, Foà R, Aster JC, Frank DA, Weinstock DM.Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):252-7.
  • Fernandes MS, Reddy MM, Gonneville JR, DeRoo SC, Podar K, Griffin JD, Weinstock DM, Sattler M.BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair.Blood. 2009 Aug 27;114(9):1813-9.
  • Brunet E, Simsek D, Tomishima M, DeKelver R, Choi VM, Gregory P, Urnov F, Weinstock DM, Jasin M.Chromosomal translocations induced at specified loci in human stem cells.Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10620-5.
  • Kim JM,Parmar K,Huang M,Weinstock DM,Ruit CA,Kutok JL,D'Andrea AD.Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.Dev Cell. 2009 Feb;16(2):314-20.
  • Weinstock DM, Brunet E, Jasin M.Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases.J Natl Cancer Inst Monogr. 2008(39):20-4.
  • Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, Dykxhoorn DM, Weinstock DM, Pfeifer GP, Lieberman J.A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.Mol Cell. 2008 Jul 11;31(1):33-46.
  • Weinstock DM, Case C Jr, Bader JL, Chao NJ, Coleman CN, Hatchett RJ, Weisdorf DJ, Confer DL.Radiological and nuclear events: contingency planning for hematologist/oncologists.Blood. 2008 Jun 15;111(12):5440-5. Review.
  • Weinstock DM, Brunet E, Jasin M.Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.Nat Cell Biol. 2007 Aug;9(8):978-81.
  • Perales MA, Ishill N, Lomazow WA, Weinstock DM, Papadopoulos EB, Dastigir H, Chiu M, Boulad F, Castro-Malaspina HR, Heller G, Jakubowski AA, O'Reilly RJ, Small TN, Young JW, Kernan NA.Long-term follow-up of patients treated with daclizumab for steroid-refractory acute graft-vs-host disease.Bone Marrow Transplant. 2007 Sep;40(5):481-6.
  • Weinstock DM, Richardson CA, Elliott B, Jasin M.Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells.DNA Repair (Amst). 2006 Sep 8;5(9-10):1065-74. Review.
  • Weinstock DM, Nakanishi K, Helgadottir HR, Jasin M.Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase.Methods Enzymol. 2006;409:524-40.
  • Weinstock DM, Zuccotti G.Adamantane resistance in influenza A.JAMA. 2006 Feb 22;295(8):934-6.
  • Weinstock DM, Ambrossi GG, Brennan C, Kiehn TE, Jakubowski A.Preemptive diagnosis and treatment of Epstein-Barr virus-associated post transplant lymphoproliferative disorder after hematopoietic stem cell transplant: an approach in development.Bone Marrow Transplant. 2006 Mar;37(6):539-46. Review.
  • Weinstock DM, Jasin M.Alternative pathways for the repair of RAG-induced DNA breaks.Mol Cell Biol. 2006 Jan;26(1):131-9.
  • Weinstock DM, Elliott B, Jasin M.A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair.Blood. 2006 Jan 15;107(2):777-80.
  • Weinstock DM, Gubareva LV, Zuccotti G.Prolonged shedding of multidrug-resistant influenza A virus in an immunocompromised patient.N Engl J Med. 2003 Feb 27;348(9):867-8.