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Elaine A. Elion, PhD


  • Elion EA, Sahoo R.Analysis of mitogen-activated protein kinase activity in yeast.Methods Mol Biol. 2010;661:387-99.
  • Elion EA.Detection of protein-protein interactions by coprecipitation.Curr Protoc Protein Sci. 2007 Aug;Chapter 19:Unit 19.4.
  • Yu L, Qi M, Sheff MA, Elion EA.Counteractive Control of Polarized Morphogenesis during Mating by Mitogen-activated Protein Kinase Fus3 and G1 Cyclin-dependent Kinase.Mol Biol Cell. 2008 Apr;19(4):1739-52.
  • Qi M, Elion EA.MAP kinase pathways.J Cell Sci. 2005 Aug 15;118(Pt 16):3569-72.
  • Cherkasova VA, McCully R, Wang Y, Hinnebusch A, Elion EA.A novel functional link between MAP kinase cascades and the Ras/cAMP pathway that regulates survival.Curr Biol. 2003 Jul 15;13(14):1220-6.
  • Wang Y, Elion EA.Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components.Mol Biol Cell. 2003 Jun;14(6):2543-58.
  • Lee BN, Elion EA.The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12679-84.
  • Mahanty SK, Wang Y, Farley FW, Elion EA.Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade.Cell. 1999 Aug 20;98(4):501-12.
  • Choi KY, Kranz JE, Mahanty SK, Park KS, Elion EA.Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity.Mol Biol Cell. 1999 May;10(5):1553-68.
  • Farley FW, Satterberg B, Goldsmith EJ, Elion EA.Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p.Genetics. 1999 Apr;151(4):1425-44.
  • Cherkasova V, Lyons DM, Elion EA.Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p.Genetics. 1999 Mar;151(3):989-1004.
  • Leza MA, Elion EA.POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2.Genetics. 1999 Feb;151(2):531-43.
  • Elion EA.Routing MAP kinase cascades.Science. 1998 Sep 11;281(5383):1625-6.
  • Feng Y, Song LY, Kincaid E, Mahanty SK, Elion EA.Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11.Curr Biol. 1998 Feb 26;8(5):267-78.
  • Lyons DM, Mahanty SK, Choi KY, Manandhar M, Elion EA.The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae.Mol Cell Biol. 1996 Aug;16(8):4095-106.
  • Elion EA, Trueheart J, Fink GR.Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.J Cell Biol. 1995 Sep;130(6):1283-96.
  • Choi KY, Satterberg B, Lyons DM, Elion EA.Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae.Cell. 1994 Aug 12;78(3):499-512.
  • Kranz JE, Satterberg B, Elion EA.The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.Genes Dev. 1994 Feb 1;8(3):313-27.
  • Elion EA, Satterberg B, Kranz JE.FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.Mol Biol Cell. 1993 May;4(5):495-510.
  • Elion EA, Brill JA, Fink GR.FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9392-6.
  • Elion EA, Brill JA, Fink GR.Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions.Cold Spring Harb Symp Quant Biol. 1991;56:41-9.
  • Elion EA, Grisafi PL, Fink GR.FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation.Cell. 1990 Feb 23;60(4):649-64.
  • Elion EA, Warner JR.An RNA polymerase I enhancer in Saccharomyces cerevisiae.Mol Cell Biol. 1986 Jun;6(6):2089-97.
  • Elion EA, Warner JR.The major promoter element of rRNA transcription in yeast lies 2 kb upstream.Cell. 1984 Dec;39(3 Pt 2):663-73.