Malcolm Whitman, PhD

Publications

Ho DM, Yeo CY, Whitman M.The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo.Mech Dev.;127(9-12):485-95.
20807570
Danciu TE, Whitman M.Oxidative stress drives disulfide bond formation between basic helix-loop-helix transcription factors.J Cell Biochem. 2010 Feb 1;109(2):417-24.
19950203
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A.Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.Science.
19498172
Onuma Y,Watanabe A,Aburatani H,Asashima M,Whitman M.TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates.Zoolog Sci. 2008 Jul;25(7):706-13.
18828657
Ho DM, Whitman M.TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.Dev Biol. 2008 Mar 1;315(1):203-16.
18234181
Anderson SB, Goldberg AL, Whitman M.Identification of a novel pool of extracellular pro-myostatin in skeletal muscle.J Biol Chem. 2008 Mar 14;283(11):7027-35.
18175804
Onuma Y, Asashima M, Whitman M.A Serpin family gene, Protease nexin-1 has an activity distinct from protease inhibition in early Xenopus embryos.Mech Dev. 2006 Jun;123(6):463-71.
16797167
Kolk SM, Whitman MC, Yun ME, Shete P, Donoghue MJ.A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex.Mol Cell Neurosci. 2006 May-Jun;32(1-2):200-14.
16858776
Ho DM, Chan J, Bayliss P, Whitman M.Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo.Dev Biol. 2006 Jul 15;295(2):730-42.
16684517
Weisberg E, Winnier GE, Chen X, Farnsworth CL, Hogan BL, Whitman M.A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.Mech Dev. 1998 Dec;79(1-2):17-27.
10349617
Chen X, Weisberg E, Fridmacher V, Watanabe M, Naco G, Whitman M.Smad4 and FAST-1 in the assembly of activin-responsive factor.Nature. 1997 Sep 4;389(6646):85-9.
9288972
LaBonne C, Whitman M.Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling.Dev Biol. 1997 Mar 1;183(1):9-20.
9119118
Chen X, Rubock MJ, Whitman M.A transcriptional partner for MAD proteins in TGF-beta signalling.Nature. 1996 Oct 24;383(6602):691-6.
8878477
Huang HC, Murtaugh LC, Vize PD, Whitman M.Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.EMBO J. 1995 Dec 1;14(23):5965-73.
8846789
LaBonne C, Burke B, Whitman M.Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development.Development. 1995 May;121(5):1475-86.
7789277
LaBonne C, Whitman M.Mesoderm induction by activin requires FGF-mediated intracellular signals.Development. 1994 Feb;120(2):463-72.
8149921
Whitman M, Melton DA.Involvement of p21ras in Xenopus mesoderm induction.Nature. 1992 May 21;357(6375):252-4.
1589022
Thomsen G, Woolf T, Whitman M, Sokol S, Vaughan J, Vale W, Melton DA.Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.Cell. 1990 Nov 2;63(3):485-93.
2225062
Hall DJ, Jones SD, Kaplan DR, Whitman M, Rollins BJ, Stiles CD.Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA.Mol Cell Biol. 1989 Apr;9(4):1705-13.
2542776
Whitman M, Downes CP, Keeler M, Keller T, Cantley L.Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate.Nature. 1988 Apr 14;332(6165):644-6.
2833705
Whitman M, Kaplan D, Roberts T, Cantley L.Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation.Biochem J. 1987 Oct 1;247(1):165-74.
2825654
Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, Cantley L, Roberts TM.Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.Cell. 1987 Sep 25;50(7):1021-9.
2441878
Kaplan DR, Whitman M, Schaffhausen B, Raptis L, Garcea RL, Pallas D, Roberts TM, Cantley L.Phosphatidylinositol metabolism and polyoma-mediated transformation.Proc Natl Acad Sci U S A. 1986 Jun;83(11):3624-8.
2424008
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM.Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation.Nature. 1985 May 16-22;315(6016):239-42.
2987699
Sugimoto Y, Whitman M, Cantley LC, Erikson RL.Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.Proc Natl Acad Sci U S A. 1984 Apr;81(7):2117-21.
6326105

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DF/HCC Directory Login Update Member Profile Change Account Settings Applying for Membership Benefits Requirements Responsibilities	Malcolm Whitman, PhD Publications Ho DM, Yeo CY, Whitman M.The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo.Mech Dev.;127(9-12):485-95. 20807570 Danciu TE, Whitman M.Oxidative stress drives disulfide bond formation between basic helix-loop-helix transcription factors.J Cell Biochem. 2010 Feb 1;109(2):417-24. 19950203 Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A.Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.Science. 19498172 Onuma Y,Watanabe A,Aburatani H,Asashima M,Whitman M.TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates.Zoolog Sci. 2008 Jul;25(7):706-13. 18828657 Ho DM, Whitman M.TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.Dev Biol. 2008 Mar 1;315(1):203-16. 18234181 Anderson SB, Goldberg AL, Whitman M.Identification of a novel pool of extracellular pro-myostatin in skeletal muscle.J Biol Chem. 2008 Mar 14;283(11):7027-35. 18175804 Onuma Y, Asashima M, Whitman M.A Serpin family gene, Protease nexin-1 has an activity distinct from protease inhibition in early Xenopus embryos.Mech Dev. 2006 Jun;123(6):463-71. 16797167 Kolk SM, Whitman MC, Yun ME, Shete P, Donoghue MJ.A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex.Mol Cell Neurosci. 2006 May-Jun;32(1-2):200-14. 16858776 Ho DM, Chan J, Bayliss P, Whitman M.Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo.Dev Biol. 2006 Jul 15;295(2):730-42. 16684517 Weisberg E, Winnier GE, Chen X, Farnsworth CL, Hogan BL, Whitman M.A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis.Mech Dev. 1998 Dec;79(1-2):17-27. 10349617 Chen X, Weisberg E, Fridmacher V, Watanabe M, Naco G, Whitman M.Smad4 and FAST-1 in the assembly of activin-responsive factor.Nature. 1997 Sep 4;389(6646):85-9. 9288972 LaBonne C, Whitman M.Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling.Dev Biol. 1997 Mar 1;183(1):9-20. 9119118 Chen X, Rubock MJ, Whitman M.A transcriptional partner for MAD proteins in TGF-beta signalling.Nature. 1996 Oct 24;383(6602):691-6. 8878477 Huang HC, Murtaugh LC, Vize PD, Whitman M.Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.EMBO J. 1995 Dec 1;14(23):5965-73. 8846789 LaBonne C, Burke B, Whitman M.Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development.Development. 1995 May;121(5):1475-86. 7789277 LaBonne C, Whitman M.Mesoderm induction by activin requires FGF-mediated intracellular signals.Development. 1994 Feb;120(2):463-72. 8149921 Whitman M, Melton DA.Involvement of p21ras in Xenopus mesoderm induction.Nature. 1992 May 21;357(6375):252-4. 1589022 Thomsen G, Woolf T, Whitman M, Sokol S, Vaughan J, Vale W, Melton DA.Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.Cell. 1990 Nov 2;63(3):485-93. 2225062 Hall DJ, Jones SD, Kaplan DR, Whitman M, Rollins BJ, Stiles CD.Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA.Mol Cell Biol. 1989 Apr;9(4):1705-13. 2542776 Whitman M, Downes CP, Keeler M, Keller T, Cantley L.Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate.Nature. 1988 Apr 14;332(6165):644-6. 2833705 Whitman M, Kaplan D, Roberts T, Cantley L.Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation.Biochem J. 1987 Oct 1;247(1):165-74. 2825654 Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, Cantley L, Roberts TM.Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.Cell. 1987 Sep 25;50(7):1021-9. 2441878 Kaplan DR, Whitman M, Schaffhausen B, Raptis L, Garcea RL, Pallas D, Roberts TM, Cantley L.Phosphatidylinositol metabolism and polyoma-mediated transformation.Proc Natl Acad Sci U S A. 1986 Jun;83(11):3624-8. 2424008 Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM.Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation.Nature. 1985 May 16-22;315(6016):239-42. 2987699 Sugimoto Y, Whitman M, Cantley LC, Erikson RL.Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.Proc Natl Acad Sci U S A. 1984 Apr;81(7):2117-21. 6326105
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