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Jeffrey A. Meyerhardt, MD, MPH

Publications

  • Imamura Y, Lochhead P, Yamauchi M, Kuchiba A, Qian ZR, Liao X, Nishihara R, Jung S, Wu K, Nosho K, Wang YE, Peng S, Bass AJ, Haigis KM, Meyerhardt JA, Chan AT, Fuchs CS, Ogino S.Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.Mol Cancer. 2014;13(1):135.
    24885062
  • Rosenthal MH, Kim KW, Fuchs CS, Meyerhardt JA, Ramaiya NH.Relationships between KRAS mutation status and baseline radiographic distribution of disease in patients with stage IV colorectal cancer.Abdom Imaging. 2014 Jun 7.
    24906690
  • Wolpin BM, Rubinson DA, Wang X, Chan JA, Cleary JM, Enzinger PC, Fuchs CS, McCleary NJ, Meyerhardt JA, Ng K, Schrag D, Sikora AL, Spicer BA, Killion L, Mamon H, Kimmelman AC.Phase II and Pharmacodynamic Study of Autophagy Inhibition Using Hydroxychloroquine in Patients With Metastatic Pancreatic Adenocarcinoma.Oncologist. 2014 Jun;19(6):637-8.
    24821822
  • Jeon JY, Meyerhardt JA.Can we change the past for colorectal cancer patients and how do we move forward?.Cancer. 2014 Mar 3.
    24591002
  • Clancy TE, Meyerhardt JA.Perioperative chemotherapy for colorectal cancer liver metastases.Oncology (Huntingt). 2013 Nov;27(11):1088-90.
    24575536
  • Ng K, Scott JB, Drake BF, Chan AT, Hollis BW, Chandler PD, Bennett GG, Giovannucci EL, Gonzalez-Suarez E, Meyerhardt JA, Emmons KM, Fuchs CS.Dose response to vitamin D supplementation in African Americans: results of a 4-arm, randomized, placebo-controlled trial.Am J Clin Nutr. 2014 Mar;99(3):587-98.
    24368437
  • Abrams TA, Meyer G, Schrag D, Meyerhardt JA, Moloney J, Fuchs CS.Chemotherapy usage patterns in a US-wide cohort of patients with metastatic colorectal cancer.Journal of the National Cancer Institute. 2014 Feb;106(2):djt371.
    24511107
  • Brooks GA, Abrams TA, Meyerhardt JA, Enzinger PC, Sommer K, Dalby CK, Uno H, Jacobson JO, Fuchs CS, Schrag D.Identification of Potentially Avoidable Hospitalizations in Patients With GI Cancer.J Clin Oncol. 2014 Jan 13.
    24419123
  • Meyerhardt JA, Mangu PB, Flynn PJ, Korde L, Loprinzi CL, Minsky BD, Petrelli NJ, Ryan K, Schrag DH, Wong SL, Benson AB, .Follow-up care, surveillance protocol, and secondary prevention measures for survivors of colorectal cancer: American Society of Clinical Oncology clinical practice guideline endorsement.J Clin Oncol. 2013 Dec 10;31(35):4465-70.
    24220554
  • Ogino S, Liao X, Imamura Y, Yamauchi M, McCleary NJ, Ng K, Niedzwiecki D, Saltz LB, Mayer RJ, Whittom R, Hantel A, Benson AB, Mowat RB, Spiegelman D, Goldberg RM, Bertagnolli MM, Meyerhardt JA, Fuchs CS, .Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.Journal of the National Cancer Institute. 2013 Dec 4;105(23):1789-98.
    24231454
  • Jeon J, Sato K, Niedzwiecki D, Ye X, Saltz LB, Mayer RJ, Mowat RB, Whittom R, Hantel A, Benson A, Wigler DS, Atienza D, Messino M, Kindler H, Venook A, Fuchs CS, Meyerhardt JA.Impact of physical activity after cancer diagnosis on survival in patients with recurrent colon cancer: Findings from CALGB 89803/Alliance.Clin Colorectal Cancer. 2013 Dec;12(4):233-8.
    24035029
  • Chan JA, Blaszkowsky L, Stuart K, Zhu AX, Allen J, Wadlow R, Ryan DP, Meyerhardt J, Gonzalez M, Regan E, Zheng H, Kulke MH.A prospective, phase 1/2 study of everolimus and temozolomide in patients with advanced pancreatic neuroendocrine tumor.Cancer. 2013 Sep 1;119(17):3212-8.
    23733618
  • André T, Iveson T, Labianca R, Meyerhardt JA, Souglakos I, Yoshino T, Paul J, Sobrero A, Taieb J, Shields AF, Ohtsu A, Grothey A, Sargent DJ, .The IDEA (International Duration Evaluation of Adjuvant Chemotherapy) Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX (FOLFOX4 or Modified FOLFOX6) or XELOX (3 versus 6 months) Regimen for Patients with Stage III Colon Cancer: Trial Design and Current Status.Current Colorectal Cancer Reports. 2013;9:261-269.
    24032000
  • Lochhead P, Kuchiba A, Imamura Y, Liao X, Yamauchi M, Nishihara R, Qian ZR, Morikawa T, Shen J, Meyerhardt JA, Fuchs CS, Ogino S.Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.Journal of the National Cancer Institute. 2013 Aug 7;105(15):1151-6.
    23878352
  • Jeon JY, Meyerhardt JA.Exercise after cancer diagnosis: time to get moving.Oncology (Huntingt). 2013 Jun;27(6):585-6, 588.
    23909074
  • Meyerhardt JA.We are what we eat, or are we?.J Clin Oncol. 2013 Aug 1;31(22):2763-4.
    23816969
  • McCleary NJ, Meyerhardt JA, Green E, Yothers G, de Gramont A, Van Cutsem E, O'Connell M, Twelves CJ, Saltz LB, Haller DG, Sargent DJ.Impact of age on the efficacy of newer adjuvant therapies in patients with stage II/III colon cancer: findings from the ACCENT database.J Clin Oncol. 2013 Jul 10;31(20):2600-6.
    23733765
  • Lee DH, Kim JY, Lee MK, Lee C, Min JH, Jeong DH, Lee JW, Chu SH, Meyerhardt JA, Ligibel J, Jones LW, Kim NK, Jeon JY.Effects of a 12-week home-based exercise program on the level of physical activity, insulin, and cytokines in colorectal cancer survivors: a pilot study.Support Care Cancer. 2013 May 2.
    23636649
  • Yamauchi M, Lochhead P, Imamura Y, Kuchiba A, Liao X, Qian ZR, Nishihara R, Morikawa T, Shima K, Wu K, Giovannucci E, Meyerhardt JA, Fuchs CS, Chan AT, Ogino S.Physical Activity, Tumor PTGS2 Expression, and Survival in Patients with Colorectal Cancer.Cancer Epidemiol Biomarkers Prev. 2013 Apr 29.
    23629521
  • Meyerhardt JA.The impact of glycemic levels in patients with colon cancer.Clin Adv Hematol Oncol. 2013 Feb;11(2):93-4.
    23598910
  • Je Y, Jeon JY, Giovannucci EL, Meyerhardt JA.Association between physical activity and mortality in colorectal cancer: A Meta-analysis of prospective cohort studies.Int J Cancer. 2013 Apr 12.
    23580314
  • Wolpin BM, Ng K, Zhu AX, Abrams T, Enzinger PC, McCleary NJ, Schrag D, Kwak EL, Allen JN, Bhargava P, Chan JA, Goessling W, Blaszkowsky LS, Supko JG, Elliot M, Sato K, Regan E, Meyerhardt JA, Fuchs CS.Multicenter Phase II Study of Tivozanib (AV-951) and Everolimus (RAD001) for Patients With Refractory, Metastatic Colorectal Cancer.Oncologist. 2013 Apr 11.
    23580238
  • Strosberg J, Chan J, Ryan DP, Meyerhardt JA, Fuchs CS, Abrams TA, Regan EM, Brady R, Weber J, Campos T, Kvols L, Kulke MH.A multi-institutional, phase II open-label study of ganitumab (AMG 479) in advanced carcinoid and pancreatic neuroendocrine tumors.Endocr. Relat. Cancer. 2013 Apr 9.
    23572164
  • Khoury MJ, Lam TK, Ioannidis JP, Hartge P, Spitz MR, Buring JE, Chanock SJ, Croyle RT, Goddard KA, Ginsburg GS, Herceg Z, Hiatt RA, Hoover RN, Hunter DJ, Kramer BS, Lauer MS, Meyerhardt JA, Olopade OI, Palmer JR, Sellers TA, Seminara D, Ransohoff DF, Rebbeck TR, Tourassi G, Winn DM, Zauber A, Schully SD.Transforming epidemiology for 21st century medicine and public health.Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):508-16.
    23462917
  • Ogino S, Lochhead P, Chan AT, Nishihara R, Cho E, Wolpin BM, Meyerhardt JA, Meissner A, Schernhammer ES, Fuchs CS, Giovannucci E.Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease.Mod Pathol. 2013 Apr;26(4):465-84.
    23307060
  • Lee MS, Mamon HJ, Hong TS, Choi NC, Fidias PM, Kwak EL, Meyerhardt JA, Ryan DP, Bueno R, Donahue DM, Jaklitsch MT, Lanuti M, Rattner DW, Fuchs CS, Enzinger PC.Preoperative cetuximab, irinotecan, Cisplatin, and radiation therapy for patients with locally advanced esophageal cancer.Oncologist. 2013;18(3):281-7.
    23429739
  • Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD.The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design.Cancer Causes Control. 2013 Apr;24(4):695-704.
    23378138
  • Zhu AX, Ancukiewicz M, Supko JG, Sahani DV, Blaszkowsky LS, Meyerhardt JA, Abrams TA, McCleary NJ, Bhargava P, Muzikansky A, Sheehan S, Regan E, Vasudev E, Knowles M, Fuchs CS, Ryan DP, Jain RK, Duda DG.Efficacy, safety, pharmacokinetics, and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: a phase II study.Clin Cancer Res. 2013 Mar 15;19(6):1557-66.
    23362324
  • Je Y, Lee JE, Ma J, Zhang X, Cho E, Rosner B, Selhub J, Fuchs CS, Meyerhardt J, Giovannucci E.Prediagnostic plasma vitamin B6 (pyridoxal 5'-phosphate) and survival in patients with colorectal cancer.Cancer Causes Control. 2013 Apr;24(4):719-29.
    23340905
  • Morikawa T, Kuchiba A, Lochhead P, Nishihara R, Yamauchi M, Imamura Y, Liao X, Qian ZR, Ng K, Chan AT, Meyerhardt JA, Giovannucci E, Fuchs CS, Ogino S.Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with β-catenin (CTNNB1) status.Cancer Res. 2013 Mar 1;73(5):1600-10.
    23442321
  • Ahn KY, Hur H, Kim DH, Min J, Jeong DH, Chu SH, Lee JW, Ligibel JA, Meyerhardt JA, Jones LW, Jeon JY, Kim NK.The effects of inpatient exercise therapy on the length of hospital stay in stages I-III colon cancer patients: randomized controlled trial.Int J Colorectal Dis. 2013 Feb 17.
    23417645
  • Jeon JY, Jeong DH, Park MG, Lee JW, Chu SH, Park JH, Lee MK, Sato K, Ligibel JA, Meyerhardt JA, Kim NK.Impact of diabetes on oncologic outcome of colorectal cancer patients: colon vs. rectal cancer.PLoS ONE. 2013;8(2):e55196.
    23405123
  • McCleary NJ, Wigler D, Berry D, Sato K, Abrams T, Chan J, Enzinger P, Ng K, Wolpin B, Schrag D, Fuchs CS, Hurria A, Meyerhardt JA.Feasibility of computer-based self-administered cancer-specific geriatric assessment in older patients with gastrointestinal malignancy.Oncologist. 2013;18(1):64-72.
    23287880
  • Van Loon K, Wigler D, Niedzwiecki D, Venook AP, Fuchs C, Blanke C, Saltz L, Goldberg RM, Meyerhardt JA.Comparison of Dietary and Lifestyle Habits Among Stage III and Metastatic Colorectal Cancer Patients: Findings from CALGB 89803 and CALGB 80405.Clin Colorectal Cancer. 2013 Jan 11.
    23317558
  • Chung JY, Lee DH, Park JH, Lee MK, Kang DW, Min J, Kim DI, Jeong DH, Kim NK, Meyerhardt JA, Jones LW, Jeon JY.Patterns of physical activity participation across the cancer trajectory in colorectal cancer survivors.Support Care Cancer. 2013 Jan 6.
    23292698
  • Ogino S, Nishihara R, Lochhead P, Imamura Y, Kuchiba A, Morikawa T, Yamauchi M, Liao X, Qian ZR, Sun R, Sato K, Kirkner GJ, Wang M, Spiegelman D, Meyerhardt JA, Schernhammer ES, Chan AT, Giovannucci E, Fuchs CS.Prospective Study of Family History and Colorectal Cancer Risk by Tumor LINE-1 Methylation Level.Journal of the National Cancer Institute. 2012 Nov 21.
    23175808
  • Meyerhardt JA, Sato K, Niedzwiecki D, Ye C, Saltz LB, Mayer RJ, Mowat RB, Whittom R, Hantel A, Benson A, Wigler DS, Venook A, Fuchs CS.Dietary Glycemic Load and Cancer Recurrence and Survival in Patients with Stage III Colon Cancer: Findings From CALGB 89803.Journal of the National Cancer Institute. 2012 Nov 21;104(22):1702-11.
    23136358
  • Lochhead P, Imamura Y, Morikawa T, Kuchiba A, Yamauchi M, Liao X, Qian ZR, Nishihara R, Wu K, Meyerhardt JA, Fuchs CS, Ogino S.Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.Eur J Cancer. 2012 Dec;48(18):3405-13.
    22840368
  • McCleary NJ, Odejide O, Szymonifka J, Ryan D, Hezel A, Meyerhardt JA.Safety and Effectiveness of Oxaliplatin-Based Chemotherapy Regimens in Adults 75 Years and Older with Colorectal Cancer.Clin Colorectal Cancer. 2012 Oct 24.
    23102897
  • Liao X, Lochhead P, Nishihara R, Morikawa T, Kuchiba A, Yamauchi M, Imamura Y, Qian ZR, Baba Y, Shima K, Sun R, Nosho K, Meyerhardt JA, Giovannucci E, Fuchs CS, Chan AT, Ogino S.Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.N Engl J Med. 2012 Oct 25;367(17):1596-606.
    23094721
  • Morikawa T, Tanaka N, Kuchiba A, Nosho K, Yamauchi M, Hornick JL, Swanson RS, Chan AT, Meyerhardt JA, Huttenhower C, Schrag D, Fuchs CS, Ogino S.Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.Arch Surg. 2012 Aug;147(8):715-23.
    22508672
  • Imamura Y, Morikawa T, Liao X, Lochhead P, Kuchiba A, Yamauchi M, Qian ZR, Nishihara R, Meyerhardt JA, Haigis KM, Fuchs CS, Ogino S.Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.Clin Cancer Res. 2012 Sep 1;18(17):4753-63.
    22753589
  • Chan JA, Stuart K, Earle CC, Clark JW, Bhargava P, Miksad R, Blaszkowsky L, Enzinger PC, Meyerhardt JA, Zheng H, Fuchs CS, Kulke MH.Prospective study of bevacizumab plus temozolomide in patients with advanced neuroendocrine tumors.J Clin Oncol. 2012 Aug 20;30(24):2963-8.
    22778320
  • Demark-Wahnefried W, Platz EA, Ligibel JA, Blair CK, Courneya KS, Meyerhardt JA, Ganz PA, Rock CL, Schmitz KH, Wadden T, Philip EJ, Wolfe B, Gapstur SM, Ballard-Barbash R, McTiernan A, Minasian L, Nebeling L, Goodwin PJ.The role of obesity in cancer survival and recurrence.Cancer Epidemiol Biomarkers Prev. 2012 Aug;21(8):1244-59.
    22695735
  • Sanoff HK, Carpenter WR, Stürmer T, Goldberg RM, Martin CF, Fine JP, McCleary NJ, Meyerhardt JA, Niland J, Kahn KL, Schymura MJ, Schrag D.Effect of adjuvant chemotherapy on survival of patients with stage III colon cancer diagnosed after age 75 years.J Clin Oncol. 2012 Jul 20;30(21):2624-34.
    22665536
  • Meyerhardt JA, Ancukiewicz M, Abrams TA, Schrag D, Enzinger PC, Chan JA, Kulke MH, Wolpin BM, Goldstein M, Blaszkowsky L, Zhu AX, Elliott M, Regan E, Jain RK, Duda DG.Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer.PLoS ONE. 2012;7(6):e38231.
    22701615
  • Baba Y, Nosho K, Shima K, Hayashi M, Meyerhardt JA, Chan AT, Giovannucci E, Fuchs CS, Ogino S.Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.Cancer. 2011 Apr 1;117(7):1399-408.
    21425139
  • Ng K, Sargent DJ, Goldberg RM, Meyerhardt JA, Green EM, Pitot HC, Hollis BW, Pollak MN, Fuchs CS.Vitamin D Status in Patients With Stage IV Colorectal Cancer: Findings From Intergroup Trial N9741.J Clin Oncol. 2011 Mar 21.
    21422438
  • Meyerhardt JA.Adjuvant Therapy for Stage II and III Colon Cancer.Clin Adv Hematol Oncol. 2010 Nov;8(11):772-4.
    21326156
  • Chan JA, Blaszkowsky LS, Enzinger PC, Ryan DP, Abrams TA, Zhu AX, Temel JS, Schrag D, Bhargava P, Meyerhardt JA, Wolpin BM, Fidias P, Zheng H, Florio S, Regan E, Fuchs CS.A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma.Ann Oncol. 2011 Jan 7.
    21217058
  • Shima K, Nosho K, Baba Y, Cantor M, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.Int J Cancer. 2011 Mar 1;128(5):1080-94.
    20473920
  • Bao Y, Nimptsch K, Meyerhardt J, Chan AT, Ng K, Michaud DS, Brand-Miller JC, Willett WC, Giovannucci E, Fuchs CS.Dietary insulin load, dietary insulin index, and colorectal cancer.Cancer Epidemiol Biomarkers Prev. 2010 Dec;19(12):3020-6.
    20924099
  • Baba Y, Nosho K, Shima K, Hayashi M, Meyerhardt JA, Chan AT, Giovannucci E, Fuchs CS, Ogino S.Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.Cancer. 2010 Nov 8.
    21061337
  • Nosho K, Baba Y, Tanaka N, Shima K, Hayashi M, Meyerhardt JA, Giovannucci E, Dranoff G, Fuchs CS, Ogino S.Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.J Pathol. 2010 Dec;222(4):350-66.
    20927778
  • Kulke MH, Chan JA, Meyerhardt JA, Zhu AX, Abrams TA, Blaszkowsky LS, Regan E, Sidor C, Fuchs CS.A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors.Cancer Chemother Pharmacol. 2010 Oct 20.
    20960192
  • Ng K, Meyerhardt JA, Chan JA, Niedzwiecki D, Hollis DR, Saltz LB, Mayer RJ, Benson AB, Schaefer PL, Whittom R, Hantel A, Goldberg RM, Fuchs CS.Multivitamin use is not associated with cancer recurrence or survival in patients with stage III colon cancer: findings from CALGB 89803.J Clin Oncol. 2010 Oct 1;28(28):4354-63.
    20805450
  • Baba Y, Nosho K, Shima K, Meyerhardt JA, Chan AT, Engelman JA, Cantley LC, Loda M, Giovannucci E, Fuchs CS, Ogino S.Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.Br J Cancer. 2010 Sep 28;103(7):1025-33.
    20808308
  • Goodwin PJ, Meyerhardt JA, Hursting SD.Host factors and cancer outcome.J Clin Oncol. 2010 Sep 10;28(26):4019-21.
    20697081
  • Meyerhardt JA, Ma J, Courneya KS.Energetics in colorectal and prostate cancer.J Clin Oncol. 2010 Sep 10;28(26):4066-73. Review.
    20644082
  • Baba Y, Nosho K, Shima K, Irahara N, Chan AT, Meyerhardt JA, Chung DC, Giovannucci EL, Fuchs CS, Ogino S.HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.Am J Pathol. 2010 May;176(5):2292-301.
    20363910
  • McCleary NJ, Meyerhardt JA.New developments in the adjuvant therapy of stage II colon cancer. Risk assessments in the older patient.Oncology (Huntingt). 2010 Jan;24(1 Suppl 1):3-8.
    20225605
  • McCleary NJ, Niedzwiecki D, Hollis D, Saltz LB, Schaefer P, Whittom R, Hantel A, Benson A, Goldberg R, Meyerhardt JA.Impact of smoking on patients with stage III colon cancer: results from Cancer and Leukemia Group B 89803.Cancer. 2010 Feb 15;116(4):957-66.
    20052723
  • Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Mino-Kenudson M, Giovannucci EL, Meyerhardt JA, Fuchs CS.Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction.Am J Gastroenterol. 2010 Feb;105(2):420-33.
    19809407
  • Zhu AX, Meyerhardt JA, Blaszkowsky LS, Kambadakone AR, Muzikansky A, Zheng H, Clark JW, Abrams TA, Chan JA, Enzinger PC, Bhargava P, Kwak EL, Allen JN, Jain SR, Stuart K, Horgan K, Sheehan S, Fuchs CS, Ryan DP, Sahani DV.Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study.Lancet Oncol. 2010 Jan;11(1):48-54.
    19932054
  • Meyerhardt JA, Giovannucci EL, Ogino S, Kirkner GJ, Chan AT, Willett W, Fuchs CS.Physical activity and male colorectal cancer survival.Arch Intern Med. 2009 Dec 14;169(22):2102-8.
    20008694
  • Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Schaefer P, Whittom R, Hantel A, Benson AB, Goldberg RM, Bertagnolli MM, Fuchs CS, , , , .KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803.Clin Cancer Res. 2009 Dec 1;15(23):7322-9.
    19934290
  • Myers AP, Meyerhardt JA, Cantley LC.Getting knit-PI3Ky: PIK3CA mutation status to direct multimodality therapy?.Clin Cancer Res. 2009 Nov 15;15(22):6748-50.
    19903790
  • Nosho K, Kure S, Irahara N, Shima K, Baba Y, Spiegelman D, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
    19686742
  • Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS.Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
    19825961
  • Kure S, Nosho K, Baba Y, Irahara N, Shima K, Ng K, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
    19789368
  • Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Meyerhardt JA, Fuchs CS.Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.J Clin Oncol. 2009 Sep 20;27(27):4591-8.
    19704056
  • Meyerhardt JA, Ogino S, Kirkner GJ, Chan AT, Wolpin B, Ng K, Nosho K, Shima K, Giovannucci EL, Loda M, Fuchs CS.Interaction of molecular markers and physical activity on mortality in patients with colon cancer.Clin Cancer Res. 2009 Sep 15;15(18):5931-6.
    19723652
  • Ogino S, Nosho K, Shima K, Baba Y, Irahara N, Kirkner GJ, Hazra A, De Vivo I, Giovannucci EL, Meyerhardt JA, Fuchs CS.p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21.
    19723919
  • Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA.Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.Br J Cancer. 2009 Aug 4;101(3):465-72.
    19603024
  • Baba Y, Nosho K, Shima K, Freed E, Irahara N, Philips J, Meyerhardt JA, Hornick JL, Shivdasani RA, Fuchs CS, Ogino S.Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.Clin Cancer Res. 2009 Jul 15;15(14):4665-73.
    19584150
  • Ogino S, Nosho K, Irahara N, Kure S, Shima K, Baba Y, Toyoda S, Chen L, Giovannucci EL, Meyerhardt JA, Fuchs CS.A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
    19549773
  • Zhu AX,Sahani DV,Duda DG,di Tomaso E,Ancukiewicz M,Catalano OA,Sindhwani V,Blaszkowsky LS,Yoon SS,Lahdenranta J,Bhargava P,Meyerhardt J,Clark JW,Kwak EL,Hezel AF,Miksad R,Abrams TA,Enzinger PC,Fuchs CS,Ryan DP,Jain RK.Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study.J Clin Oncol. 2009 Jun 20;27(18):3027-35.
    19470923
  • Ogino S, Shima K, Nosho K, Irahara N, Baba Y, Wolpin BM, Giovannucci EL, Meyerhardt JA, Fuchs CS.A cohort study of p27 localization in colon cancer, body mass index, and patient survival.Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
    19505918
  • Kulke MH,Hornick JL,Frauenhoffer C,Hooshmand S,Ryan DP,Enzinger PC,Meyerhardt JA,Clark JW,Stuart K,Fuchs CS,Redston MS.O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.Clin Cancer Res. 2009 Jan 1;15(1):338-45.
    19118063
  • Fuchs CS,Goldberg RM,Sargent DJ,Meyerhardt JA,Wolpin BM,Green EM,Pitot HC,Pollak M.Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.Clin Cancer Res. 2008 Dec 15;14(24):8263-9.
    19073970
  • Wolpin BM,Meyerhardt JA,Chan AT,Ng K,Chan JA,Wu K,Pollak MN,Giovannucci EL,Fuchs CS.Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.J Clin Oncol. 2009 Jan 10;27(2):176-85.
    19064975
  • Wolpin BM,Hezel AF,Abrams T,Blaszkowsky LS,Meyerhardt JA,Chan JA,Enzinger PC,Allen B,Clark JW,Ryan DP,Fuchs CS.Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.J Clin Oncol. 2009 Jan 10;27(2):193-8.
    19047305
  • Ogino S,Nosho K,Meyerhardt JA,Kirkner GJ,Chan AT,Kawasaki T,Giovannucci EL,Loda M,Fuchs CS.Cohort study of fatty acid synthase expression and patient survival in colon cancer.J Clin Oncol. 2008 Dec 10;26(35):5713-20.
    18955444
  • Ogino S,Nosho K,Kirkner GJ,Kawasaki T,Meyerhardt JA,Loda M,Giovannucci EL,Fuchs CS.CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.Gut. 2009 Jan;58(1):90-6.
    18832519
  • Bracht LK,Wen P,Meyerhardt JA,Kulke MH,Hornick JL,Redston M,LaFrankie DC,Black PM,Kesari S,Norden A,Drappatz J.DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.J Clin Oncol. 2008 Oct 10;26(29):4843-4.
    18779600
  • Meyerhardt JA,Niedzwiecki D,Hollis D,Saltz LB,Mayer RJ,Nelson H,Whittom R,Hantel A,Thomas J,Fuchs CS.Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803.J Clin Oncol. 2008 Sep 1;26(25):4109-15.
    18757324
  • Wolpin BM,Wei EK,Ng K,Meyerhardt JA,Chan JA,Selhub J,Giovannucci EL,Fuchs CS.Prediagnostic plasma folate and the risk of death in patients with colorectal cancer.J Clin Oncol. 2008 Jul 1;26(19):3222-8.
    18591557
  • Ng K,Meyerhardt JA,Wu K,Feskanich D,Hollis BW,Giovannucci EL,Fuchs CS.Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.J Clin Oncol. 2008 Jun 20;26(18):2984-91.
    18565885
  • Chan JA,Meyerhardt JA,Niedzwiecki D,Hollis D,Saltz LB,Mayer RJ,Thomas J,Schaefer P,Whittom R,Hantel A,Goldberg RM,Warren RS,Bertagnolli M,Fuchs CS.Association of family history with cancer recurrence and survival among patients with stage III colon cancer.JAMA. 2008 Jun 4;299(21):2515-23.
    18523220
  • Bass AJ, Meyerhardt JA, Chan JA, Giovannucci EL, Fuchs CS.Family history and survival after colorectal cancer diagnosis.Cancer. 2008 Mar 15;112(6):1222-9.
    18219663
  • Meyerhardt JA, Zhu AX, Stuart K, Ryan DP, Blaszkowsky L, Lehman N, Earle CC, Kulke MH, Bhargava P, Fuchs CS.Phase-II Study of Gemcitabine and Cisplatin in Patients with Metastatic Biliary and Gallbladder Cancer.Dig Dis Sci. 2008 Feb;53(2):564-70.
    17597402
  • Kawasaki T, Ohnishi M, Nosho K, Suemoto Y, Kirkner GJ, Meyerhardt JA, Fuchs CS, Ogino S.CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.Mod Pathol. 2008 Mar;21(3):245-55.
    18204436
  • Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Wu K, Fuchs CS.Aspirin dose and duration of use and risk of colorectal cancer in men.Gastroenterology. 2008 Jan;134(1):21-8.
    18005960
  • Kulke MH, Blaszkowsky LS, Ryan DP, Clark JW, Meyerhardt JA, Zhu AX, Enzinger PC, Kwak EL, Muzikansky A, Lawrence C, Fuchs CS.Capecitabine plus erlotinib in gemcitabine-refractory advanced pancreatic cancer.J Clin Oncol. 2007 Oct 20;25(30):4787-92.
    17947726
  • Ogino S, Kawasaki T, Kirkner GJ, Suemoto Y, Meyerhardt JA, Fuchs CS.Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.Gut. 2007 Nov;56(11):1564-71.
    17339237
  • Ogino S, Hazra A, Tranah GJ, Kirkner GJ, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Meyerhardt JA, Hunter DJ, Fuchs CS.MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.Carcinogenesis. 2007 Sep;28(9):1985-90.
    17621591
  • Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Dehari R, Meyerhardt JA, Fuchs CS, Ogino S.Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.Neoplasia. 2007 Jul;9(7):569-77.
    17710160
  • Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Hu FB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS.Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer.JAMA. 2007 Aug 15;298(7):754-64.
    17699009
  • Meyerhardt JA, Clark JW, Supko JG, Eder JP, Ogino S, Stewart CF, D'Amato F, Dancey J, Enzinger PC, Zhu AX, Ryan DP, Earle CC, Mayer RJ, Michelini A, Kinsella K, Fuchs CS.Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer.Cancer Chemother Pharmacol. 2007 Oct;60(5):661-70.
    17216531
  • Meyerhardt J, Stuart K, Fuchs C, Zhu A, Earle C, Bhargava P, Blaszkowsky L, Enzinger P, Mayer R, Battu S, Lawrence C, Ryan D.Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastastic colorectal cancer.Ann Oncol. 2007 Jul;18(7):1185-9.
    17483115
  • Zhu AX, Stuart K, Blaszkowsky LS, Muzikansky A, Reitberg DP, Clark JW, Enzinger PC, Bhargava P, Meyerhardt JA, Horgan K, Fuchs CS, Ryan DP.Phase 2 study of cetuximab in patients with advanced hepatocellular carcinoma.Cancer. 2007 Aug 1;110(3):581-9.
    17583545
  • Wolpin BM, Meyerhardt JA, Mamon HJ, Mayer RJ.Adjuvant treatment of colorectal cancer.CA Cancer J Clin. 2007 May-Jun;57(3):168-85. Review.
    17507442
  • Enzinger PC, Benedetti JK, Meyerhardt JA, McCoy S, Hundahl SA, Macdonald JS, Fuchs CS.Impact of hospital volume on recurrence and survival after surgery for gastric cancer.Ann Surg. 2007 Mar;245(3):426-34.
    17435550
  • Ogino S, Meyerhardt JA, Kawasaki T, Clark JW, Ryan DP, Kulke MH, Enzinger PC, Wolpin BM, Loda M, Fuchs CS.CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.Virchows Arch. 2007 May;450(5):529-537.
    17372756
  • Zhu AX, Clark JW, Ryan DP, Meyerhardt JA, Enzinger PC, Earle CC, Fuchs CS, Regan E, Anbe H, Houghton M, Zhang J, Urrea P, Kulke MH.Phase I and pharmacokinetic study of S-1 administered for 14 days in a 21-day cycle in patients with advanced upper gastrointestinal cancer.Cancer Chemother Pharmacol. 2007 Feb;59(3):285-93.
    16786333
  • Chan JA, Meyerhardt JA, Chan AT, Giovannucci EL, Colditz GA, Fuchs CS.Hormone replacement therapy and survival after colorectal cancer diagnosis.J Clin Oncol. 2006 Dec 20;24(36):5680-6.
    17179103
  • Wolpin BM, Clark JW, Meyerhardt JA, Earle CC, Ryan DP, Enzinger PC, Zhu AX, Blaszkowsky L, Battu S, Fuchs CS.Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer.Clin Colorectal Cancer. 2006 Sep;6(3):208-13.
    17026790
  • Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA, Heymach JV, Fogler WE, Sidor C, Michelini A, Kinsella K, Venook AP, Fuchs CS.Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors.J Clin Oncol. 2006 Aug 1;24(22):3555-61.
    16877721
  • Meyerhardt JA, Giovannucci EL, Holmes MD, Chan AT, Chan JA, Colditz GA, Fuchs CS.Physical activity and survival after colorectal cancer diagnosis.J Clin Oncol. 2006 Aug 1;24(22):3527-34.
    16822844
  • Meyerhardt JA, Heseltine D, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Nelson H, Whittom R, Hantel A, Schilsky RL, Fuchs CS.Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803.J Clin Oncol. 2006 Aug 1;24(22):3535-41.
    16822843
  • Meyerhardt JA, Heseltine D, Ogino S, Clark JW, Enzinger PC, Ryan DP, Earle CC, Zhu AX, Fuchs CS.Efficacy of cetuximab after treatment with oral epidermal growth factor receptor tyrosine kinase inhibitor-based chemotherapy in metastatic colorectal cancer.Clin Colorectal Cancer. 2006 May;6(1):59-65.
    16796793
  • Meyerhardt JA, Zhu AX, Enzinger PC, Ryan DP, Clark JW, Kulke MH, Earle CC, Vincitore M, Michelini A, Sheehan S, Fuchs CS.Phase II study of capecitabine, oxaliplatin, and erlotinib in previously treated patients with metastastic colorectal cancer.J Clin Oncol. 2006 Apr 20;24(12):1892-7.
    16622264
  • Ogino S, Brahmandam M, Cantor M, Namgyal C, Kawasaki T, Kirkner G, Meyerhardt JA, Loda M, Fuchs CS.Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.Mod Pathol. 2006 Jan;19(1):59-68.
    16118624
  • Meyerhardt JA, Heseltine D, Campos H, Holmes MD, Willett WC, Winer EP, Enzinger PC, Bunnell CA, Kulke MH, Fuchs CS.Assessment of a dietary questionnaire in cancer patients receiving cytotoxic chemotherapy.J Clin Oncol. 2005 Nov 20;23(33):8453-60.
    16293876
  • Ogino S, Meyerhardt JA, Cantor M, Brahmandam M, Clark JW, Namgyal C, Kawasaki T, Kinsella K, Michelini AL, Enzinger PC, Kulke MH, Ryan DP, Loda M, Fuchs CS.Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
    16166444
  • Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Curhan GC, Fuchs CS.Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer.JAMA. 2005 Aug 24;294(8):914-23.
    16118381
  • Meyerhardt JA, Sloan JA, Sargent DJ, Goldberg DJ, Pollak M, Morton RK, Williamson SK, Findlay BP, Fuchs CS.The associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer.J Am Diet Assoc. In press;In press:In press.
  • Meyerhardt JA, Sloan JA, Sargent DJ, Goldberg RM, Pollak M, Morton RF, Ramanathan RK, Williamson SK, Findlay BP, Fuchs CS.Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer.Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1402-10.
    15941948
  • Meyerhardt JA, Mayer RJ.Systemic therapy for colorectal cancer.N Engl J Med. 2005 Feb 3;352(5):476-87.
    15689586
  • Meyerhardt JA, Fuchs CS.Epidermal growth factor receptor inhibitors and colorectal cancer.Oncology (Huntingt). 2004 Dec;18(14 Suppl 14):35-8.
    15685832
  • Meyerhardt JA, Kwok A, Ratain MJ, McGovren JP, Fuchs CS.Relationship of baseline serum bilirubin to efficacy and toxicity of single-agent irinotecan in patients with metastatic colorectal cancer.J Clin Oncol. 2004 Apr 15;22(8):1439-46.
    15084617
  • Meyerhardt JA, Tepper JE, Niedzwiecki D, Hollis DR, McCollum AD, Brady D, O'Connell MJ, Mayer RJ, Cummings B, Willett C, Macdonald JS, Benson AB, Fuchs CS.Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114.J Clin Oncol. 2004 Feb 15;22(4):648-57.
    14966087
  • Meyerhardt JA, Tepper JE, Niedzwiecki D, Hollis DR, Schrag D, Ayanian JZ, O'Connell MJ, Weeks JC, Mayer RJ, Willett CG, MacDonald JS, Benson AB, Fuchs CS.Impact of hospital procedure volume on surgical operation and long-term outcomes in high-risk curatively resected rectal cancer: findings from the Intergroup 0114 Study.J Clin Oncol. 2004 Jan 1;22(1):166-74.
    14701779
  • Meyerhardt JA, Catalano PJ, Schrag D, Ayanian JZ, Haller DG, Mayer RJ, Macdonald JS, Benson AB, Fuchs CS.Association of hospital procedure volume and outcomes in patients with colon cancer at high risk for recurrence.Ann Intern Med. 2003 Oct 21;139(8):649-57.
    14568853
  • Meyerhardt JA, Catalano PJ, Haller DG, Mayer RJ, Benson AB, Macdonald JS, Fuchs CS.Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma.Cancer. 2003 Aug 1;98(3):484-95.
    12879464
  • Meyerhardt JA, Mayer RJ.Follow-up strategies after curative resection of colorectal cancer.Semin Oncol. 2003 Jun;30(3):349-60.
    12870136
  • Meyerhardt JA, Fuchs CS.Adjuvant therapy in gastric cancer: can we prevent recurrences?.Oncology (Huntingt). 2003 May;17(5):714-21, 728; discussion 7.
    12800796
  • Meyerhardt JA, Catalano PJ, Haller DG, Mayer RJ, Macdonald JS, Benson AB, Fuchs CS.Impact of diabetes mellitus on outcomes in patients with colon cancer.J Clin Oncol. 2003 Feb 1;21(3):433-40.
    12560431
  • Meyerhardt JA, Fuchs CS.Chemotherapy options for gastric cancer.Semin Radiat Oncol. 2002 Apr;12(2):176-86.
    11979419
  • Reyes-Mgica M, Meyerhardt JA, Rzasa J, Rimm DL, Johnson KR, Wheelock MJ, Reale MA.Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells.Lab Invest. 2001 Feb;81(2):201-10.
    11232642