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Jack Szostak

Publications

  • Powner MW, Zheng SL, Szostak JW.Multicomponent assembly of proposed DNA precursors in water.J Am Chem Soc. 2012 Aug 22;134(33):13889-95.
    22839703
  • Budin I, Szostak JW.Physical effects underlying the transition from primitive to modern cell membranes.Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5249-54.
    21402937
  • Subtelny AO, Hartman MC, Szostak JW.Optimal codon choice can improve the efficiency and fidelity of N-methyl amino Acid incorporation into peptides by in-vitro translation.Angew Chem Int Ed Engl. 2011 Mar 28;50(14):3164-7.
    21381166
  • Powner MW, Sutherland JD, Szostak JW.Chemoselective multicomponent one-pot assembly of purine precursors in water.J Am Chem Soc. 2011 Mar 23;133(11):4149-50.
    21361381
  • Powner MW, Sutherland JD, Szostak JW.Chemoselective multicomponent one-pot assembly of purine precursors in water.J Am Chem Soc. 2010 Nov 24;132(46):16677-88.
    21043502
  • Szostak JW.DNA Ends: Just the Beginning (Nobel Lecture).Angew Chem Int Ed Engl. 2010 Oct 4;49(41):7386-404.
    20818632
  • Elenko MP, Szostak JW, van Oijen AM.Single-molecule binding experiments on long time scales.Rev Sci Instrum. 2010 Aug;81(8):083705.
    20815611
  • Schrum JP, Zhu TF, Szostak JW.The Origins of Cellular Life.Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a002212. Review.
    20484387
  • Zhu TF,Szostak JW.Coupled Growth and Division of Model Protocell Membranes.J Am Chem Soc. 2009 Apr 22;131(15):5705-13.
    19323552
  • Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA.Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.J Am Chem Soc. 2010 Apr 28;132(16):5880-5.
    20359213
  • Lin S, Horning DP, Szostak JW, Chaput JC.Conformational analysis of DNA repair intermediates by time-resolved fluorescence spectroscopy.J Phys Chem A. 2009 Sep 3;113(35):9585-7.
    19673467
  • Elenko MP, Szostak JW, van Oijen AM.Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.J Am Chem Soc. 2009 Jul 29;131(29):9866-7.
    19572753
  • Szostak JW.Origins of life: Systems chemistry on early Earth.Nature. 2009 May 14;459(7244):171-2.
    19444196
  • Litovchick A,Szostak JW.Retraction for Litovchick and Szostak, Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display.Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7263.
    19380733
  • Zhu TF,Szostak JW.Preparation of large monodisperse vesicles.PLoS ONE. 2009;4(4):e5009.
    19347043
  • Chen JJ,Tsai CH,Cai X,Horhota AT,McLaughlin LW,Szostak JW.Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.PLoS ONE. 2009;4(3):e4949.
    19305495
  • Chen JJ,Cai X,Szostak JW.N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system.J Am Chem Soc. 2009 Feb 18;131(6):2119-21.
    19166350
  • Litovchick A,Szostak JW.Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display.Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15293-8.
    18824687
  • Mansy SS,Szostak JW.Thermostability of model protocell membranes.Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13351-5.
    18768808
  • Mansy SS,Schrum JP,Krishnamurthy M,Tobe S,Treco DA,Szostak JW.Template-directed synthesis of a genetic polymer in a model protocell.Nature. 2008 Jul 3;454(7200):122-5.
    18528332
  • Subtelny AO, Hartman MC, Szostak JW.Ribosomal synthesis of N-methyl peptides.J Am Chem Soc. 2008 May 14;130(19):6131-6.
    18402453
  • Monnard PA, Szostak JW.Metal-ion catalyzed polymerization in the eutectic phase in water-ice: A possible approach to template-directed RNA polymerization.J Inorg Biochem. 2008 May;102(5-6):1104-11.
    18329104
  • Hartman MC, Josephson K, Lin CW, Szostak JW.An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.PLoS ONE. 2007;2(10):e972.
    17912351
  • Tsai CH, Chen J, Szostak JW.Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template.Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14598-603.
    17785419
  • Seelig B, Szostak JW.Selection and evolution of enzymes from a partially randomized non-catalytic scaffold.Nature. 2007 Aug 16;448(7155):828-31.
    17700701
  • Mansy SS, Zhang J, Kummerle R, Nilsson M, Chou JJ, Szostak JW, Chaput JC.Structure and evolutionary analysis of a non-biological ATP-binding protein.J Mol Biol. 2007 Aug 10;371(2):501-13.
    17583732
  • Hartman MC, Josephson K, Szostak JW.Enzymatic aminoacylation of tRNA with unnatural amino acids.Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4356-61.
    16537388
  • Cho GS, Szostak JW.Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display.Chem Biol. 2006 Feb;13(2):139-47.
    16492562
  • Hanczyc MM, Fujikawa SM, Szostak JW.Experimental models of primitive cellular compartments: encapsulation, growth, and division.Science. 2003 Oct 24;302(5645):618-22.
    14576428