• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

Catherine J. Wu, MD

Publications

  • Landau DA, Carter SL, Getz G, Wu CJ.Clonal evolution in hematological malignancies and therapeutic implications.Leukemia. 2014 Jan;28(1):34-43.
    23979521
  • Bachireddy P, Hainz U, Rooney M, Pozdnyakova O, Aldridge J, Zhang W, Liao X, Hodi FS, O'Connell K, Haining WN, Goldstein NR, Canning CM, Soiffer RJ, Ritz J, Hacohen N, Alyea EP, Kim HT, Wu CJ.Reversal of in situ T cell exhaustion during effective human anti-leukemia responses to donor lymphocyte infusion.Blood..
  • Burkhardt UE, Hainz U, Stevenson K, Goldstein NR, Pasek M, Naito M, Wu D, Ho VT, Alonso A, Hammond NN, Wong J, Sievers QL, Brusic A, McDonough SM, Zeng W, Perrin A, Brown JR, Canning CM, Koreth J, Cutler C, Armand P, Neuberg D, Lee JS, Antin JH, Mulligan RC, Sasada T, Ritz J, Soiffer RJ, Dranoff G, Alyea EP, Wu CJ.Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells.J Clin Invest. 2013 Sep 3;123(9):3756-65.
    23912587
  • Wan Y, Wu CJ.SF3B1 mutations in chronic lymphocytic leukemia.Blood. 2013 Jun 6;121(23):4627-34.
    23568491
  • Landau DA, Carter SL, Stojanov P, McKenna A, Stevenson K, Lawrence MS, Sougnez C, Stewart C, Sivachenko A, Wang L, Wan Y, Zhang W, Shukla SA, Vartanov A, Fernandes SM, Saksena G, Cibulskis K, Tesar B, Gabriel S, Hacohen N, Meyerson M, Lander ES, Neuberg D, Brown JR, Getz G, Wu CJ.Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.Cell. 2013 Feb 14;152(4):714-26.
    23415222
  • Shalek AK, Gaublomme JT, Wang L, Yosef N, Chevrier N, Andersen MS, Robinson JT, Pochet N, Neuberg D, Gertner RS, Amit I, Brown JR, Hacohen N, Regev A, Wu CJ, Park H.Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia.Nano Lett. 2012 Dec 12;12(12):6498-504.
    23190424
  • Brusic A, Hainz U, Wadleigh M, Neuberg D, Su M, Canning CM, Deangelo DJ, Stone RM, Lee JS, Mulligan RC, Ritz J, Dranoff G, Sasada T, Wu CJ.Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.Oncoimmunology. 2012 Oct 1;1(7):1095-1103.
    23170257
  • Wu CJ.CLL clonal heterogeneity: an ecology of competing subpopulations.Blood. 2012 Nov 15;120(20):4117-8.
    23160186
  • Davids MS, Deng J, Wiestner A, Lannutti BJ, Wang L, Wu CJ, Wilson WH, Brown JR, Letai A.Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.Blood. 2012 Oct 25;120(17):3501-9.
    22955911
  • Cai A, Keskin DB, Deluca DS, Alonso A, Zhang W, Zhang GL, Hammond NN, Nardi V, Stone RM, Neuberg D, Sidney J, Brusic V, Wu CJ.Mutated BCR-ABL Generates Immunogenic T-cell Epitopes in CML Patients.Clin Cancer Res. 2012 Oct 15;18(20):5761-72.
    22912393
  • Naito M, Hainz U, Burkhardt UE, Fu B, Ahove D, Stevenson KE, Rajasagi M, Zhu B, Alonso A, Witten E, Matsuoka KI, Neuberg D, Duke-Cohan JS, Wu CJ, Freeman GJ.CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells.Cancer Immunol Immunother. 2012 Aug 25.
    22926059
  • Brown JR, Hanna M, Tesar B, Werner L, Pochet N, Asara JM, Wang YE, Dal Cin P, Fernandes SM, Thompson C, Macconaill L, Wu CJ, Van de Peer Y, Correll M, Regev A, Neuberg D, Freedman AS.Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia.Clin Cancer Res. 2012 Jul 15;18(14):3791-802.
    22623730
  • Biernacki MA, Tai YT, Zhang GL, Alonso A, Zhang W, Prabhala R, Zhang L, Munshi N, Neuberg D, Soiffer RJ, Ritz J, Alyea EP, Brusic V, Anderson KC, Wu CJ.Novel myeloma-associated antigens revealed in the context of syngeneic hematopoietic stem cell transplantation.Blood. 2012 Mar 29;119(13):3142-50.
    22267603
  • Chapman M, Warren EH, Wu CJ.Applications of next-generation sequencing to blood and marrow transplantation.Biol Blood Marrow Transplant. 2012 Jan;18(1 Suppl):S151-60.
    22226099
  • Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K, Werner L, Sivachenko A, DeLuca DS, Zhang L, Zhang W, Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, Cibulskis K, Tesar B, Sievers QL, Shefler E, Gabriel S, Hacohen N, Reed R, Meyerson M, Golub TR, Lander ES, Neuberg D, Brown JR, Getz G, Wu CJ.SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.N Engl J Med. 2011 Dec 29;365(26):2497-506.
    22150006
  • Brusic A, Wu CJ.Enhancing graft-versus-leukemia after transplant: the rise of anti-cancer vaccines.Front Biosci. 2012;17:635-55.
    22201766
  • Huynh H, Zheng J, Umikawa M, Silvany R, Xie XJ, Wu CJ, Holzenberger M, Wang Q, Zhang CC.Components of the hematopoietic compartments in tumor stroma and tumor-bearing mice.PLoS ONE. 2011;6(3):e18054.
    21464968
  • Lin Y, Zhang L, Cai AX, Lee M, Zhang W, Neuberg D, Canning CM, Soiffer RJ, Alyea EP, Ritz J, Hacohen N, Means TK, Wu CJ.Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans.J Clin Invest. 2011 Mar 14.
    21403403
  • Anderson KS, Zeng W, Sasada T, Choi J, Riemer AB, Su M, Drakoulakos D, Kang YJ, Brusic V, Wu C, Reinherz EL.Impaired tumor antigen processing by immunoproteasome-expressing CD40-activated B: cells and dendritic cells.Cancer Immunol Immunother. 2011 Mar 13.
    21400024
  • Deluca DS, Marina O, Ray S, Zhang GL, Wu CJ, Brusic V.Data processing and analysis for protein microarrays.Methods Mol Biol. 2011;723:337-47.
    21370075
  • Marina O, Duke-Cohan JS, Wu CJ.A coprecipitation-based validation methodology for interactions identified using protein microarrays.Methods Mol Biol. 2011;723:239-54.
    21370070
  • Hsieh MM, Wu CJ, Tisdale JF.In mixed hematopoietic chimerism, the donor red cells win.Haematologica. 2011 Jan;96(1):13-5.
    21193430
  • Koreth J, Biernacki M, Aldridge J, Kim HT, Alyea EP, Armand P, Cutler C, Ho VT, Wu CJ, Antin JH, Soiffer RJ.Syngeneic Donor Hematopoietic Stem Cell Transplantation is Associated with High Rates of Engraftment Syndrome.Biol Blood Marrow Transplant. 2010 Sep 23.
    20870027
  • Zhang W, Choi J, Zeng W, Rogers SA, Alyea EP, Rheinwald JG, Canning CM, Brusic V, Sasada T, Reinherz EL, Ritz J, Soiffer RJ, Wu CJ.Graft-versus-leukemia antigen CML66 elicits coordinated B-cell and T-cell immunity after donor lymphocyte infusion.Clin Cancer Res. 2010 May 15;16(10):2729-39.
    20460482
  • Ofran Y, Kim HT, Brusic V, Blake L, Mandrell M, Wu CJ, Sarantopoulos S, Bellucci R, Keskin DB, Soiffer RJ, Antin JH, Ritz J.Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes.Clin Cancer Res. 2010 Mar 1;16(5):1642-51.
    20160060
  • Marina O, Hainz U, Biernacki MA, Zhang W, Cai A, Duke-Cohan JS, Liu F, Brusic V, Neuberg D, Kutok JL, Alyea EP, Canning CM, Soiffer RJ, Ritz J, Wu CJ.Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens.Cancer Res. 2010 Feb 15;70(4):1344-55.
    20124481
  • Biernacki MA, Marina O, Zhang W, Liu F, Bruns I, Cai A, Neuberg D, Canning CM, Alyea EP, Soiffer RJ, Brusic V, Ritz J, Wu CJ.Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.Cancer Res. 2010 Feb 1;70(3):906-15.
    20103624
  • Wu CJ, Ritz J.Revealing tumor immunity after hematopoietic stem cell transplantation.Clin Cancer Res. 2009 Jul 15;15(14):4515-7.
    19584145
  • Krishnamurti L,Kharbanda S,Biernacki MA,Zhang W,Baker KS,Wagner JE,Wu CJ.Stable long-term donor engraftment following reduced-intensity hematopoietic cell transplantation for sickle cell disease.Biol Blood Marrow Transplant. 2008 Nov;14(11):1270-8.
    18940682
  • Armistead PM,Mohseni M,Gerwin R,Walsh EC,Iravani M,Chahardouli B,Rostami S,Zhang W,Neuberg D,Rioux J,Ghavamzadeh A,Ritz J,Antin JH,Wu CJ.Erythroid-lineage-specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation.Exp Hematol. 2008 Sep;36(9):1205-15.
    18550258
  • Marina O, Biernacki MA, Brusic V, Wu CJ.A concentration-dependent analysis method for high density protein microarrays.J Proteome Res. 2008 May;7(5):2059-68.
    18393456
  • Lin CJ, Pan CF, Wu CJ, Chen HH, Kao CR, Lee CC.A giant gastric ulcer mimicking carcinoma in a renal transplant recipient with CMV infection.South Med J. 2008 Mar;101(3):327.
    18364669
  • Volarevic M, Smolic R, Wu CH, Wu GY.Potential role of RNAi in the treatment of HCV infection.Expert Rev Anti Infect Ther. 2007 Oct;5(5):823-31. Review.
    17914916
  • Wu CJ, Ritz J.Induction of tumor immunity following allogeneic stem cell transplantation.Adv Immunol. 2006;90:133-73. Review.
    16730263
  • Wu CJ, Krishnamurti L, Kutok JL, Biernacki M, Rogers S, Zhang W, Antin JH, Ritz J.Evidence for ineffective erythropoiesis in severe sickle cell disease.Blood. 2005 Nov 15;106(10):3639-45.
    16091448
  • Wu CJ, Biernacki M, Kutok JL, Rogers S, Chen L, Yang XF, Soiffer RJ, Ritz J.Graft-versus-leukemia target antigens in chronic myelogenous leukemia are expressed on myeloid progenitor cells.Clin Cancer Res. 2005 Jun 15;11(12):4504-11.
    15958636
  • Bellucci R, Alyea EP, Chiaretti S, Wu CJ, Zorn E, Weller E, Wu B, Canning C, Schlossman R, Munshi NC, Anderson KC, Ritz J.Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor.Blood. 2005 May 15;105(10):3945-50.
    15692072
  • Miklos DB, Kim HT, Miller KH, Guo L, Zorn E, Lee SJ, Hochberg EP, Wu CJ, Alyea EP, Cutler C, Ho V, Soiffer RJ, Antin JH, Ritz J.Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission.Blood. 2005 Apr 1;105(7):2973-8.
    15613541
  • Yan Y, Phan L, Yang F, Talpaz M, Yang Y, Xiong Z, Ng B, Timchenko NA, Wu CJ, Ritz J, Wang H, Yang XF.A novel mechanism of alternative promoter and splicing regulates the epitope generation of tumor antigen CML66-L.J Immunol. 2004 Jan 1;172(1):651-60.
    14688378
  • Bellucci R, Wu CJ, Chiaretti S, Weller E, Davies FE, Alyea EP, Dranoff G, Anderson KC, Munshi NC, Ritz J.Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens.Blood. 2004 Jan 15;103(2):656-63.
    14563636
  • Wu CJ, Hochberg EP, Rogers SA, Kutok JL, Biernacki M, Nascimento AF, Marks P, Bridges K, Ritz J.Molecular assessment of erythroid lineage chimerism following nonmyeloablative allogeneic stem cell transplantation.Exp Hematol. 2003 Oct;31(10):924-33.
    14550808
  • Antin JH, Kim HT, Cutler C, Ho VT, Lee SJ, Miklos DB, Hochberg EP, Wu CJ, Alyea EP, Soiffer RJ.Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation.Blood. 2003 Sep 1;102(5):1601-5.
    12730113
  • Wu CJ, Neuberg D, Chillemi A, McLaughlin S, Hochberg EP, Galinsky I, DeAngelo D, Soiffer RJ, Alyea EP, Capdeville R, Stone RM, Ritz J.Quantitative monitoring of BCR/ABL transcript during STI-571 therapy.Leuk Lymphoma. 2002 Dec;43(12):2281-9.
    12613514
  • Yang XF, Wu CJ, Chen L, Alyea EP, Canning C, Kantoff P, Soiffer RJ, Dranoff G, Ritz J.CML28 is a broadly immunogenic antigen, which is overexpressed in tumor cells.Cancer Res. 2002 Oct 1;62(19):5517-22.
    12359762
  • Bellucci R, Alyea EP, Weller E, Chillemi A, Hochberg E, Wu CJ, Canning C, Schlossman R, Soiffer RJ, Anderson KC, Ritz J.Immunologic effects of prophylactic donor lymphocyte infusion after allogeneic marrow transplantation for multiple myeloma.Blood. 2002 Jun 15;99(12):4610-7.
    12036895
  • Hochberg EP, Chillemi AC, Wu CJ, Neuberg D, Canning C, Hartman K, Alyea EP, Soiffer RJ, Kalams SA, Ritz J.Quantitation of T-cell neogenesis in vivo after allogeneic bone marrow transplantation in adults.Blood. 2001 Aug 15;98(4):1116-21.
    11493459
  • Yang XF, Wu CJ, McLaughlin S, Chillemi A, Wang KS, Canning C, Alyea EP, Kantoff P, Soiffer RJ, Dranoff G, Ritz J.CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia.Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7492-7.
    11416219
  • Zorn E, Orsini E, Wu CJ, Stein B, Chillemi A, Canning C, Alyea EP, Soiffer RJ, Ritz J.A CD4+ T cell clone selected from a CML patient after donor lymphocyte infusion recognizes BCR-ABL breakpoint peptides but not tumor cells.Transplantation. 2001 Apr 27;71(8):1131-7.
    11374415
  • Wu CJ, Yang XF, McLaughlin S, Neuberg D, Canning C, Stein B, Alyea EP, Soiffer RJ, Dranoff G, Ritz J.Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia.J Clin Invest. 2000 Sep;106(5):705-14.
    10974024
  • Wu CJ, Chillemi A, Alyea EP, Orsini E, Neuberg D, Soiffer RJ, Ritz J.Reconstitution of T-cell receptor repertoire diversity following T-cell depleted allogeneic bone marrow transplantation is related to hematopoietic chimerism.Blood. 2000 Jan 1;95(1):352-9.
    10607724
  • Wu CJ, Scadden DT.Posttransplant Kaposi's sarcoma treated with paclitaxel.J Clin Oncol. 1998 Oct;16(10):3478-9.
    9779728