• Home
  • News
  • Calendar
  • About DF/HCC
  • Membership
  • Visitor Center

Gerburg Wulf, MD, PhD


  • Luo ML, Gong C, Chen CH, Lee DY, Hu H, Huang P, Yao Y, Guo W, Reinhardt F, Wulf G, Lieberman J, Zhou XZ, Song E, Lu KP.Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem-like Cell Traits in Breast Cancer.Cancer Res. 2014 May 1.
  • Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC.Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.Cell. 2013 Nov 7;155(4):844-57.
  • Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG.PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.Cell. 2013 Oct 10;155(2):397-409.
  • Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM.Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer.Cancer Discovery. 2012 Nov;2(11):1048-63.
  • Burga LN, Hu H, Juvekar A, Tung NM, Troyan SL, Hofstatter EW, Wulf GM.Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor-inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice.Breast Cancer Res. 2011 Mar 11;13(2):R30.
  • Yuan TL, Wulf G, Burga L, Cantley LC.Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations.Curr Biol. 2011 Feb 8;21(3):173-83.
  • Dohm A, Hasenkamp J, Bertsch HP, Maas JH, Truemper L, Wulf G.Progression of a CD4+/CD56+ blastic plasmacytoid DC neoplasm after initiation of extracorporeal photopheresis in an allogeneic transplant recipient.Bone Marrow Transplant. 2010 Aug 23.
  • Ryo A,Wulf G,Lee TH,Lu KP.Pinning down HER2-ER crosstalk in SMRT regulation.Trends Biochem Sci. 2009 Apr;34(4):162-5.
  • Burga LN,Tung NM,Troyan SL,Bostina M,Konstantinopoulos PA,Fountzilas H,Spentzos D,Miron A,Yassin YA,Lee BT,Wulf GM.Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers.Cancer Res. 2009 Feb 15;69(4):1273-8.
  • Lam PB,Burga LN,Wu BP,Hofstatter EW,Lu KP,Wulf GM.Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability.Mol Cancer. 2008;7:91.
  • Lu KP, Suizu F, Zhou XZ, Finn G, Lam P, Wulf G.Targeting carcinogenesis: a role for the prolyl isomerase Pin1?.Mol Carcinog. 2006 Jun;45(6):397-402. Review.
  • Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP.The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.Nature. 2006 Mar 23;440(7083):528-34.