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Darren Toh, DSc


  • Toh S, Avorn J, D'Agostino RB, Gurwitz JH, Psaty BM, Rothman KJ, Saag KG, Sturkenboom MC, Vandenbroucke JP, Winterstein AG, Strom BL.Re-using Mini-Sentinel data following rapid assessments of potential safety signals via modular analytic programs.Pharmacoepidemiol Drug Saf. 2013 Aug 7.
  • Toh S, Reichman ME, Houstoun M, Ding X, Fireman BH, Gravel E, Levenson M, Li L, Moyneur E, Shoaibi A, Zornberg G, Hennessy S.Multivariable confounding adjustment in distributed data networks without sharing of patient-level data.Pharmacoepidemiol Drug Saf. 2013 Jul 23.
  • Lo Re V, Haynes K, Goldberg D, Forde KA, Carbonari DM, Leidl KB, Hennessy S, Reddy KR, Pawloski PA, Daniel GW, Cheetham TC, Iyer A, Coughlin KO, Toh S, Boudreau DM, Selvam N, Cooper WO, Selvan MS, Vanwormer JJ, Avigan MI, Houstoun M, Zornberg GL, Racoosin JA, Shoaibi A.Validity of diagnostic codes to identify cases of severe acute liver injury in the U.S. Food and Drug Administration's Mini-Sentinel Distributed Database.Pharmacoepidemiol Drug Saf. 2013 Aug;22(8):861-72.
  • Briesacher BA, Soumerai SB, Zhang F, Toh S, Andrade SE, Wagner JL, Shoaibi A, Gurwitz JH.A critical review of methods to evaluate the impact of FDA regulatory actions.Pharmacoepidemiol Drug Saf. 2013 Jul 12.
  • Johnson KE, Beaton SJ, Andrade SE, Cheetham TC, Scott PE, Hammad TA, Dashevsky I, Cooper WO, Davis RL, Pawloski PA, Raebel MA, Smith DH, Toh S, Li DK, Haffenreffer K, Dublin S.Methods of linking mothers and infants using health plan data for studies of pregnancy outcomes.Pharmacoepidemiol Drug Saf. 2013 Jul;22(7):776-82.
  • Toh S, Gagne JJ, Rassen JA, Fireman BH, Kulldorff M, Brown JS.Confounding adjustment in comparative effectiveness research conducted within distributed research networks.Med Care. 2013 Aug;51(8 Suppl 3):S4-S10.
  • Toh S, Baker MA, Brown JS, Kornegay C, Platt R, .Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration's Mini-Sentinel program.JAMA Intern Med. 2013 May 13;173(9):817-9.
  • Li Q, Andrade SE, Cooper WO, Davis RL, Dublin S, Hammad TA, Pawloski PA, Pinheiro SP, Raebel MA, Scott PE, Smith DH, Dashevsky I, Haffenreffer K, Johnson KE, Toh S.Validation of an algorithm to estimate gestational age in electronic health plan databases.Pharmacoepidemiol Drug Saf. 2013 May;22(5):524-32.
  • Toh S, Platt R.Is size the next big thing in epidemiology?.Epidemiology. 2013 May;24(3):349-51.
  • Toh S, Li Q, Cheetham TC, Cooper WO, Davis RL, Dublin S, Hammad TA, Li DK, Pawloski PA, Pinheiro SP, Raebel MA, Scott PE, Smith DH, Bobo WV, Lawrence JM, Dashevsky I, Haffenreffer K, Avalos LA, Andrade SE.Prevalence and trends in the use of antipsychotic medications during pregnancy in the U.S., 2001-2007: a population-based study of 585,615 deliveries.Arch Womens Ment Health. 2013 Apr;16(2):149-57.
  • Avalos LA, Chen H, Yang C, Andrade SE, Cooper WO, Cheetham CT, Davis RL, Dublin S, Hammad TA, Kaplan S, Pawloski PA, Raebel MA, Scott PE, Smith DH, Toh S, Li DK.The Prevalence and Trends of Antiviral Medication Use During Pregnancy in the US: A Population-Based Study of 664,297 Deliveries in 2001-2007.Matern Child Health J. 2013 Feb 19.
  • Cutrona SL, Toh S, Iyer A, Foy S, Daniel GW, Nair VP, Ng D, Butler MG, Boudreau D, Forrow S, Goldberg R, Gore J, McManus D, Racoosin JA, Gurwitz JH.Validation of acute myocardial infarction in the Food and Drug Administration's Mini-Sentinel program.Pharmacoepidemiol Drug Saf. 2013 Jan;22(1):40-54.
  • Andrade SE, Scott PE, Davis RL, Li DK, Getahun D, Cheetham TC, Raebel MA, Toh S, Dublin S, Pawloski PA, Hammad TA, Beaton SJ, Smith DH, Dashevsky I, Haffenreffer K, Cooper WO.Validity of health plan and birth certificate data for pregnancy research.Pharmacoepidemiol Drug Saf. 2013 Jan;22(1):7-15.
  • Lawrence JM, Andrade SE, Avalos LA, Beaton SJ, Chiu VY, Davis RL, Dublin S, Pawloski PA, Raebel MA, Smith DH, Toh S, Wang JQ, Kaplan S, Amini T, Hampp C, Hammad TA, Scott PE, Cheetham TC, .Prevalence, trends, and patterns of use of antidiabetic medications among pregnant women, 2001-2007.Obstet Gynecol. 2013 Jan;121(1):106-14.
  • Toh S, Reichman ME, Houstoun M, Ross Southworth M, Ding X, Hernandez AF, Levenson M, Li L, McCloskey C, Shoaibi A, Wu E, Zornberg G, Hennessy S.Comparative risk for angioedema associated with the use of drugs that target the renin-angiotensin-aldosterone system.Arch Intern Med. 2012 Nov 12;172(20):1582-9.
  • Hansen C, Joski P, Freiman H, Andrade S, Toh S, Dublin S, Cheetham C, Cooper W, Pawloski P, Li DK, Beaton S, Kaplan S, Scott P, Hammad T, Davis R.Medication Exposure in Pregnancy Risk Evaluation Program: The Prevalence of Asthma Medication Use During Pregnancy.Matern Child Health J. 2012 Oct 30.
  • Bobo WV, Davis RL, Toh S, Li DK, Andrade SE, Cheetham TC, Pawloski P, Dublin S, Pinheiro S, Hammad T, Scott PE, Epstein RA, Arbogast PG, Morrow JA, Dudley JA, Lawrence JM, Avalos LA, Cooper WO.Trends in the use of antiepileptic drugs among pregnant women in the US, 2001-2007: a medication exposure in pregnancy risk evaluation program study.Paediatr Perinat Epidemiol. 2012 Nov;26(6):578-88.
  • Andrade SE, Davis RL, Cheetham TC, Cooper WO, Li DK, Amini T, Beaton SJ, Dublin S, Hammad TA, Pawloski PA, Raebel MA, Smith DH, Staffa JA, Toh S, Dashevsky I, Haffenreffer K, Lane K, Platt R, Scott PE.Medication Exposure in Pregnancy Risk Evaluation Program.Matern Child Health J. 2012 Oct;16(7):1349-54.
  • Toh S, García Rodríguez LA, Hernán MA.Analyzing partially missing confounder information in comparative effectiveness and safety research of therapeutics.Pharmacoepidemiol Drug Saf. 2012 May;21 Suppl 2:13-20.
  • Toh S, Li L, Harrold LR, Bayliss EA, Curtis JR, Liu L, Chen L, Grijalva CG, Herrinton LJ.Comparative safety of infliximab and etanercept on the risk of serious infections: does the association vary by patient characteristics?.Pharmacoepidemiol Drug Saf. 2012 May;21(5):524-34.
  • Toh S, Hernán MA.Causal inference from longitudinal studies with baseline randomization.Int J Biostat. 2008;4(1):Article 22.
  • Platt R, Carnahan RM, Brown JS, Chrischilles E, Curtis LH, Hennessy S, Nelson JC, Racoosin JA, Robb M, Schneeweiss S, Toh S, Weiner MG.The U.S. Food and Drug Administration's Mini-Sentinel program: status and direction.Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1:1-8.
  • Cutrona SL, Toh S, Iyer A, Foy S, Cavagnaro E, Forrow S, Racoosin JA, Goldberg R, Gurwitz JH.Design for validation of acute myocardial infarction cases in Mini-Sentinel.Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1:274-81.
  • Gagne JJ, Fireman B, Ryan PB, Maclure M, Gerhard T, Toh S, Rassen JA, Nelson JC, Schneeweiss S.Design considerations in an active medical product safety monitoring system.Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1:32-40.
  • Fireman B, Toh S, Butler MG, Go AS, Joffe HV, Graham DJ, Nelson JC, Daniel GW, Selby JV.A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent.Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1:282-90.
  • Andrade SE, Moore Simas TA, Boudreau D, Raebel MA, Toh S, Syat B, Dashevsky I, Platt R.Validation of algorithms to ascertain clinical conditions and medical procedures used during pregnancy.Pharmacoepidemiol Drug Saf. 2011 Nov;20(11):1168-76.
  • Toh S, García Rodríguez LA, Hernán MA.Confounding adjustment via a semi-automated high-dimensional propensity score algorithm: an application to electronic medical records.Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):849-57.
  • Chang CH, Toh S, Lin JW, Chen ST, Kuo CW, Chuang LM, Lai MS.Cancer risk associated with insulin glargine among adult type 2 diabetes patients--a nationwide cohort study.PLoS ONE. 2011;6(6):e21368.
  • Chen SY, Toh S.National trends in prescribing antidepressants before and after an FDA advisory on suicidality risk in youths.Psychiatr Serv. 2011 Jul;62(7):727-33.
  • Toh S, Mitchell AA, Anderka M, de Jong-van den Berg LT, Hernández-Díaz S, .Antibiotics and oral contraceptive failure - a case-crossover study.Contraception. 2011 May;83(5):418-25.
  • Toh S, Hernández-Díaz S, Logan R, Robins JM, Hernán MA.Estimating absolute risks in the presence of nonadherence: an application to a follow-up study with baseline randomization.Epidemiology. 2010 Jul;21(4):528-39.
  • Toh S, Hernández-Díaz S, Logan R, Rossouw JE, Hernán MA.Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: does the increased risk ever disappear? A randomized trial.Ann Intern Med. 2010 Feb 16;152(4):211-7.
  • Toh S, Mitchell AA, Louik C, Werler MM, Chambers CD, Hernández-Díaz S.Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction.J Clin Psychopharmacol. 2009 Dec;29(6):555-60.
  • Hernández-Díaz S, Toh S, Cnattingius S.Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study.BMJ. 2009;338:b2255.
  • Toh S, Mitchell AA, Louik C, Werler MM, Chambers CD, Hernández-Díaz S.Selective serotonin reuptake inhibitor use and risk of gestational hypertension.Am J Psychiatry. 2009 Mar;166(3):320-8.
  • Toh S, Mitchell AA, Werler MM, Hernández-Díaz S.Sensitivity and specificity of computerized algorithms to classify gestational periods in the absence of information on date of conception.Am J Epidemiol. 2008 Mar 15;167(6):633-40.
  • Toh S, Rodríguez LA, Hernández-Díaz S.Use of antidepressants and risk of lung cancer.Cancer Causes Control. 2007 Dec;18(10):1055-64.
  • Toh S, Hernández-Díaz S.Statins and fracture risk. A systematic review.Pharmacoepidemiol Drug Saf. 2007 Jun;16(6):627-40. Review.
  • Lin SJ, Lambert B, Tan H, Toh S.Frequency estimates from prescription drug datasets (revision of #04-11-066A).Pharmacoepidemiol Drug Saf. 2006 Jul;15(7):512-20.
  • Toh S.Datapoints: trends in ADHD and stimulant use among children, 1993-2003.Psychiatr Serv. 2006 Aug;57(8):1091.