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Jeffrey A. Morgan, MD

Publications

  • George S, Wang Q, Heinrich MC, Corless CL, Zhu M, Butrynski JE, Morgan JA, Wagner AJ, Choy E, Tap WD, Yap JT, Van den Abbeele AD, Manola JB, Solomon SM, Fletcher JA, von Mehren M, Demetri GD.Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial.J Clin Oncol. 2012 Jul 1;30(19):2401-7.
    22614970
  • Quek R, Wang Q, Morgan JA, Shapiro GI, Butrynski JE, Ramaiya N, Huftalen T, Jederlinic N, Manola J, Wagner AJ, Demetri GD, George S.Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.Clin Cancer Res. 2011 Feb 15;17(4):871-9.
    21177764
  • Jansen J, Nolan PL, Reeves MI, Morgan JA, Akard LP, Thompson JM, Dugan MJ, Hanks SG.Transportation of peripheral blood progenitor cell products: effect of ambient temperature.Cytotherapy. 2010 Nov;12(7):919-23.
    20429789
  • Wagner AJ, Malinowska-Kolodziej I, Morgan JA, Qin W, Fletcher CD, Vena N, Ligon AH, Antonescu CR, Ramaiya NH, Demetri GD, Kwiatkowski DJ, Maki RG.Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors.J Clin Oncol. 2010 Feb 10;28(5):835-40.
    20048174
  • Raut CP, Wang Q, Manola J, Morgan JA, George S, Wagner AJ, Butrynski JE, Fletcher CD, Demetri GD, Bertagnolli MM.Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate.Ann Surg Oncol. 2010 Feb;17(2):407-15.
    19898902
  • Theman TA, Hartzell TL, Sinha I, Polson K, Morgan J, Demetri GD, Orgill DP, George S.Recognition of a new chemotherapeutic vesicant: trabectedin (ecteinascidin-743) extravasation with skin and soft tissue damage.J Clin Oncol. 2009 Nov 20;27(33):e198-200. Review.
    19805684
  • Raut CP, Nucci MR, Wang Q, Manola J, Bertagnolli MM, Demetri GD, Morgan JA, Muto MG, Fletcher CD, George S.Predictive value of FIGO and AJCC staging systems in patients with uterine leiomyosarcoma.Eur J Cancer. 2009 Nov;45(16):2818-24.
    19647426
  • Demetri GD, Lo Russo P, MacPherson IR, Wang D, Morgan JA, Brunton VG, Paliwal P, Agrawal S, Voi M, Evans TR.Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors.Clin Cancer Res. 2009 Oct 1;15(19):6232-40.
    19789325
  • Demetri GD, Casali PG, Blay JY, von Mehren M, Morgan JA, Bertulli R, Ray-Coquard I, Cassier P, Davey M, Borghaei H, Pink D, Debiec-Rychter M, Cheung W, Bailey SM, Veronese ML, Reichardt A, Fumagalli E, Reichardt P.A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors.Clin Cancer Res. 2009 Sep 15;15(18):5910-6.
    19723647
  • Demetri GD, Heinrich MC, Fletcher JA, Fletcher CD, Van den Abbeele AD, Corless CL, Antonescu CR, George S, Morgan JA, Chen MH, Bello CL, Huang X, Cohen DP, Baum CM, Maki RG.Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure.Clin Cancer Res. 2009 Sep 15;15(18):5902-9.
    19737946
  • Quek R,Morgan JA,George S,Butrynski JE,Polson K,Meyer F,Demetri GD,Block SD.Small molecule tyrosine kinase inhibitor and depression.J Clin Oncol. 2009 Jan 10;27(2):312-3.
    19064960
  • Haining WN,Davies J,Kanzler H,Drury L,Brenn T,Evans J,Angelosanto J,Rivoli S,Russell K,George S,Sims P,Neuberg D,Li X,Kutok J,Morgan J,Wen P,Demetri G,Coffman RL,Nadler LM.CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans.Clin Cancer Res. 2008 Sep 1;14(17):5626-34.
    18765557
  • Bertagnolli MM,Morgan JA,Fletcher CD,Raut CP,Dileo P,Gill RR,Demetri GD,George S.Multimodality treatment of mesenteric desmoid tumours.Eur J Cancer. 2008 Nov;44(16):2404-10.
    18706807
  • Olawaiye AB,Morgan JA,Goodman A,Fuller AF Jr,Penson RT.Epithelioid angiosarcoma of the uterus: a review of management.Arch Gynecol Obstet. 2008 Nov;278(5):401-4. Review.
    18642010
  • Barbone D, Yang TM, Morgan JR, Gaudino G, Broaddus VC.Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids.J Biol Chem. 2008 May 9;283(19):13021-30.
    18339627
  • Patel TV, Morgan JA, Demetri GD, George S, Maki RG, Quigley M, Humphreys BD.A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib.Journal of the National Cancer Institute. 2008 Feb 20;100(4):282-4.
    18270341
  • Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, Schoen FJ, Van den Abbeele AD, Demetri GD, Force T, Chen MH.Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib.Lancet. 2007 Dec 15;370(9604):2011-9.
    18083403
  • Ito H, Hornick JL, Bertagnolli MM, George S, Morgan JA, Baldini EH, Wagner AJ, Demetri GD, Raut CP.Leiomyosarcoma of the inferior vena cava: survival after aggressive management.Ann Surg Oncol. 2007 Dec;14(12):3534-41.
    17896156
  • Desai J, Shankar S, Heinrich MC, Fletcher JA, Fletcher CD, Manola J, Morgan JA, Corless CL, George S, Tuncali K, Silverman SG, Van den Abbeele AD, van Sonnenberg E, Demetri GD.Clonal evolution of resistance to imatinib in patients with metastatic gastrointestinal stromal tumors.Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5398-405.
    17875769
  • Raut CP, Morgan JA, Ashley SW.Current issues in gastrointestinal stromal tumors: incidence, molecular biology, and contemporary treatment of localized and advanced disease.Curr Opin Gastroenterol. 2007 Mar;23(2):149-58. Review.
    17268243
  • Gerin F, Baloglu O, Morgan JA, Kesari S.Central nervous system metastases from imatinib mesylate resistant gastrointestinal stromal tumor.J Neurooncol. 2007 Apr;82(2):227-8.
    17106648
  • Desai J, Yassa L, Marqusee E, George S, Frates MC, Chen MH, Morgan JA, Dychter SS, Larsen PR, Demetri GD, Alexander EK.Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors.Ann Intern Med. 2006 Nov 7;145(9):660-4.
    17088579
  • Raut CP, Posner M, Desai J, Morgan JA, George S, Zahrieh D, Fletcher CD, Demetri GD, Bertagnolli MM.Surgical Management of Advanced Gastrointestinal Stromal Tumors After Treatment With Targeted Systemic Therapy Using Kinase Inhibitors.J Clin Oncol. 2006 May 20;24(15):2325-2331.
    16710031
  • Kulke MH, Kim H, Clark JW, Enzinger PC, Lynch TJ, Morgan JA, Vincitore M, Michelini A, Fuchs CS.A Phase II trial of gemcitabine for metastatic neuroendocrine tumors.Cancer. 2004 Sep 1;101(5):934-9.
    15329900
  • Morgan JA, Yin Y, Borowsky AD, Kuo F, Nourmand N, Koontz JI, Reynolds C, Soreng L, Griffin CA, Graeme-Cook F, Harris NL, Weisenburger D, Pinkus GS, Fletcher JA, Sklar J.Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.Cancer Res. 1999 Dec 15;59(24):6205-13.
    10626814
  • Peterson JW, Kwun BD, Teramura A, Hackett JD, Morgan JA, Nishizawa S, Bun T, Zervas NT.Immunological reaction against the aging human subarachnoid erythrocyte. A model for the onset of cerebral vasospasm after subarachnoid hemorrhage.J Neurosurg. 1989 Nov;71(5 Pt 1):718-26.
    2809726